Are there different subtypes of eosinophilic esophagitis?

Currently, eosinophilic esophagitis (EoE) is defined by the combination of clinical symptoms and pathologic findings. Patients should have symptoms of esophageal dysmotility as well as a defined (albeit somewhat arbitrarily so) level of esophageal eosinophilia. Thus, using this definition, the diagnosis of EoE is purely a phenotype, possibly allowing for multiple different etiologies to funnel into this diagnosis. In this manner, EoE is similar to other conditions that we treat, such as asthma, in which treatment strategies are evolving in an era of precision medicine.

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