Application of nanoparticle technology in the treatment of Systemic lupus erythematous

Publication date: October 2016
Source:Biomedicine & Pharmacotherapy, Volume 83
Author(s): Davood Rostamzadeh, Seyed Rasol Razavi, Shadi Esmaeili, Sanam Dolati, Majid Ahmahi, Sanam Sadreddini, Farhad Jadidi-Niaragh, Mehdi Yousefi
Systemic lupus erythematous (SLE) is a chronic heterogeneous multisystem autoimmune disease characterized by loss of tolerance to self-antigens and production of numerous autoantibodies. Current therapeutic approaches used to treat inflammatory autoimmune diseases are associated with debilitating side effects. In spite of significant advances in therapeutic options and increased understanding of the pathogenesis, novel therapeutic approaches are needed for treatment of SLE. Nanoparticle-based delivery systems that selectively deliver drugs to inflamed tissue or specific cell have the potential to improve drug delivery. This article reviews recent nanotechnology-based therapeutics strategies that are being developed for the treatment of SLE.



from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/2bait7c
via IFTTT