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Τρίτη 27 Φεβρουαρίου 2018

Liprin-{alpha}3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses [Neuroscience]

The presynaptic active zone provides sites for vesicle docking and release at central nervous synapses and is essential for speed and accuracy of synaptic transmission. Liprin-α binds to several active zone proteins, and loss-of-function studies in invertebrates established important roles for Liprin-α in neurodevelopment and active zone assembly. However, Liprin-α...

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