Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain [Plant Biology]

DNA methylation is an important epigenetic modification involved in gene regulation and transposable element silencing. Changes in DNA methylation can be heritable and, thus, can lead to the formation of stable epialleles. A well-characterized example of a stable epiallele in plants is fwa, which consists of the loss of DNA...

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