BACKGROUND: Chronic opioid use is a significant public health concern. Surgery is a risk factor for developing chronic opioid use. Patients undergoing major spine surgery frequently are prescribed opioids preoperatively and may be at risk for chronic opioid use postoperatively. The aim of this study was to investigate the incidence of and perioperative risk factors associated with chronic opioid use after major spine surgery. METHODS: The records of patients who underwent elective major spine surgery at the University of Virginia between March 2011 and February 2016 were retrospectively reviewed. The primary outcome was chronic opioid use through 12 months postoperatively. Demographic data, medical comorbidities, preoperative pain scores, and medication use including daily morphine-equivalent (ME) dose, intraoperative use of lidocaine and ketamine, estimated blood loss, postoperative pain scores and medication use, and postoperative opioid use were collected. Logistic regression models were used to examine factors associated with chronic opioid use. RESULTS: Of 1477 patient records reviewed, 412 patients (27.9%) were opioid naive and 1065 patients (72.3%) used opioids before surgery. Opioid data were available for 1325 patients, while 152 patients were lost to 12-month follow-up and were excluded. Of 958 preoperative opioid users, 498 (52.0%) remained chronic users through 12 months. There was a decrease in opioid dosage (mg ME) from preoperative to 12 months postoperatively with a mean difference of -14.7 mg ME (standard deviation, 1.57; 95% confidence interval [CI], -17.8 to -11.7). Among 367 previously opioid-naive patients, 67 (18.3%) became chronic opioid users. Factors associated with chronic opioid use were examined using logistic regression models. Preoperative opioid users were nearly 4 times more likely to be chronic opioid users through 12 months than were opioid-naive patients (odds ratio, 3.95; 95% CI, 2.51–6.33; P
http://ift.tt/2HUX8yI
Αρχειοθήκη ιστολογίου
-
►
2020
(289)
- ► Φεβρουαρίου (28)
-
►
2019
(9071)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3642)
- ► Ιανουαρίου (3200)
-
▼
2018
(39872)
- ► Δεκεμβρίου (3318)
- ► Σεπτεμβρίου (3683)
-
▼
Μαρτίου
(3597)
-
▼
Μαρ 22
(202)
- Local Anesthetic Injection Speed and Common Perone...
- Case of a fractured human bone fragment as an endo...
- Klippel-Trenaunay-Weber syndrome as a cause of chr...
- Testicular torsion in a patient with Ehlers-Danlos...
- Two cases of hypokalaemic rhabdomyolysis: same but...
- A rare presentation of haematuria: hip prosthesis ...
- Importance of source images of time-of-flight magn...
- Central congenital hypothyroidism caused by matern...
- Tarsal buckle with conjunctival prolapse following...
- Complication of intraprosthetic dislocation of dua...
- Myocarditis secondary to smallpox vaccination
- Parkinsons disease with hypocalcaemia: adult prese...
- Diffusion-weighted imaging is helpful in the accur...
- Effect of Splenectomy on Serum Cytokine Profiles i...
- A brave new world
- Intracell Heat Shock Protein 70 Expression and Nas...
- Post Parotidectomy Quality of Life in Patients wit...
- The Journal of Dermatology, Ahead of Print.
- The Journal of Dermatology, Ahead of Print.
- Intracell Heat Shock Protein 70 Expression and Nas...
- Post Parotidectomy Quality of Life in Patients wit...
- Biologicals in der Rhinologie – Individualisierte ...
- Molekulares Verstehen des Hörens – Was ändert sich...
- Das Mikrobiom – die unplanbare Größe zukünftiger T...
- HPV – Das andere Kopf-Hals-Karzinom
- Radiomics: Big Data statt Biopsie in der Zukunft?
- Robotische Chirurgie – operiert der Roboter?
- Regeneration – eine neue therapeutische Dimension ...
- Editorial Referateband 2018
- Immuntherapie – Die neue Ära in der Onkologie
- Safety of a two-day ultra-rush immunotherapy in ve...
- From the pages of allergywatch recent advances in ...
- Head &Neck, Ahead of Print.
- Head &Neck, Ahead of Print.
- Head &Neck, Ahead of Print.
- Radioguided Surgery in Primary Hyperparathyroidism...
- Head &Neck, Ahead of Print.
- Head &Neck, Ahead of Print.
- Thyroid® High-Impact Articles
- Discrepancy between clinical and pathological neck...
- Impact of Total Laryngectomy on Return to Work
- Salivary Pepsin Test: Useful and Simple Tool for t...
- Correlation Between Measures of Perceptual Assessm...
- Cleft Lip and Palate Subjects Prevalence of Abnorm...
- Efficacy of the Myofascial Pectoralis Major Flap i...
- Cochleotoxicity monitoring protocol
- Recurrent Respiratory Papillomatosis With Lung and...
- Metastasis of Gallbladder Adenocarcinoma to the Sk...
- Castleman's Disease in the Paediatric Neck
- Arteria lusoria: A rare cause of tracheal compression
- Plummer Vinson syndrome
- Comments on the Assessment of Nasal Obstruction Wi...
- A 10 Point Plan to Demonstrate the Value of Dermat...
- Reply to DR. De Cassai et al.
- Australasian Journal of Dermatology, Ahead of Print.
- Asthma Guidelines from the National Asthma Educati...
- Ataxia Telangiectasia: A Rare Neurodegenerative Di...
- Ataxia-Telangiectasia Clinical and Laboratory Feat...
- 2017 Acknowledgment of Reviewers
- Australasian Journal of Dermatology, Ahead of Print.
- Procedures for central auditory processing screeni...
- Predicting complications of major head and neck on...
- Asthma Guidelines from the National Asthma Educati...
- Ataxia Telangiectasia: A Rare Neurodegenerative Di...
- Ataxia-Telangiectasia Clinical and Laboratory Feat...
- 2017 Acknowledgment of Reviewers
- What parents are reading about laryngomalacia: Qua...
- Auditory function and motor proficiency in type 1 ...
- Nasal saline irrigation in pediatric rhinosinusiti...
- Development and validation of a quality of life in...
- A functional and anatomical comparison between two...
- Three-dimensional development of the upper dental ...
- Diagnosis and management of pediatric sinusitis: A...
- Effect of early correction of nasal septal deformi...
- Obstructive sleep apnea syndrome and growth failure
- Open resection and laryngotracheal reconstruction ...
- Surgical treatment for chronic cervical lymphadeni...
- Early experience with high-flow nasal oxygen thera...
- Systematic review/meta-analysis comparing successf...
- Trends in the management of secondary post-tonsill...
- Autosomal dominant stapes fixation, syndactyly, an...
- Swallowing outcomes in children after slide trache...
- Primary augmentation pharyngoplasty with calcium h...
- Nasal erosion as an uncommon sign of child abuse
- Clinically recorded cortical auditory evoked poten...
- Pediatric Otolaryngology: Practical Clinical Manag...
- Wheel Spokes Technique for Endothelial Keratoplast...
- Adult Coats Disease Presenting as Subfoveal Nodule
- Triamcinolone Acetonide-Assisted Descemetectomy fo...
- Intraoperative Adjunctive Mitomycin C and Cryother...
- Secondary Angle Closure due to Crystalline Lens Di...
- Hypercoagulability, Obstructive Sleep Apnea, and P...
- Hypercoagulability, Obstructive Sleep Apnea, and P...
- Self-reported Hearing Difficulty and Risk of Accid...
- A Rare Cause of Oropharyngeal and Supraglottic Air...
- Economic Interdependencies and Political Conflict:...
- APOBEC mutagenesis in drug resistance and immune e...
- Assessing the acceptability of incentivising HPV v...
- Inhibition of sodium/hydrogen exchanger 3 in the g...
- NODDI-DTI: estimating neurite orientation and disp...
-
▼
Μαρ 22
(202)
- ► Φεβρουαρίου (2693)
- ► Ιανουαρίου (3198)
-
►
2017
(41099)
- ► Δεκεμβρίου (3127)
- ► Σεπτεμβρίου (2173)
-
►
2016
(13807)
- ► Δεκεμβρίου (700)
- ► Σεπτεμβρίου (600)
- ► Φεβρουαρίου (1350)
- ► Ιανουαρίου (1400)
-
►
2015
(1500)
- ► Δεκεμβρίου (1450)
Ετικέτες
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου