Measured Glomerular Filtration Rate After Kidney Donation: No Evidence of Accelerated Decay

Background The rate of measured GFR change in kidney donors years after donation has not been adequately addressed. Whether this change is accelerated in the setting of 1 kidney is also understudied. Methods 214 randomly selected donors underwent serial GFR measurements of nonradioactive iohexol. eGFR at each visit was calculated using the CKD EPI and MDRD study equations. Results GFR visits were 4.8 ±1.3 years apart and the second occurring 16.9±9.1 years after donation. The majority (97.7%) were White; 60.8% female and 78.5% were related to their recipient. Most, 84.6%, had a GFR ≥60 ml/min/1.73m2, 14.0% had a GFR between 45-60 ml/min/1.73m2 and 1.4% had a GFR

https://ift.tt/2HiC3hS