Development of Food Protein-Induced Enterocolitis Syndrome (FPIES) to egg following Immunoglobulin E (IgE)-mediated egg allergy,

Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E (IgE)-mediated condition characterized by repetitive vomiting 1-4 hours after ingestion of the particular food accompanied by additional symptoms such as lethargy, pallor or diarrhea.1 Atypical FPIES characterizes patients who are noted to have IgE-mediated sensitization to the FPIES-inducing food,2 and has been associated with an increased likelihood of persistent FPIES.3 A clinical conversion from an FPIES phenotype to an IgE-mediated phenotype to the same food has been described.

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