A march by any other name

The allergic (or atopic) march refers to the natural history of allergic diseases as they develop during infancy and childhood. The march conventionally begins with atopic dermatitis (AD) and progresses to IgE-mediated food allergy (IgE-FA), asthma, and allergic rhinitis (AR).1 The observation that allergic manifestations tend to develop in this stereotyped progression stems from decades of observational research, including birth cohort studies. It has also been the basis for large, longitudinal studies of individual disease associations.

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