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Τετάρτη 29 Νοεμβρίου 2017

Apical polarization and lumenogenesis: The apicosome sheds new light

Establishment of apico–basal polarity is critical for the lumenal epiblast-like morphogenesis of human pluripotent stem cells (hPSCs). In this issue, Taniguchi et al. (2017. J Cell Biol. http://ift.tt/2inEsAQ) describe a structure called the apicosome, generated in single hPSCs, that allows them to self-organize and form the lumenal epiblast-like stage.



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