The dual personality of temperate phages – as infectious lytic phages or prophages integrated within the bacterial genome – creates a complex interaction with bacterial hosts. The cover image represents these two-sides of the life-history of temperate phage: one, lysogeny, involves hiding out in the host chromosome, the other, lysis, involves killing the host cell to release viral particles. [Image created by Emma Harrison] Read the review essay, article number 1700112, by Harrison and Brockhurst to find out more.
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