Αρχειοθήκη ιστολογίου

Τρίτη 6 Μαρτίου 2018

Evaluation of Interleukin-1β Level and Oxidative Status in Gingival Crevicular Fluid during Rapid Maxillary Expansion

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Publication date: Available online 6 March 2018
Source:Archives of Oral Biology
Author(s): Nur Ozel, Alev Aksoy, Fatma Yesim Kırzıoglu, Duygu Kumbul Doguc, Tutku Atış Aksoy
ObjectivesThe levels of interleukin-1β (IL-1β), nitric oxide (NO), total antioxidant capacity (TAC), and total oxidant status (TOS) in gingival crevicular fluid (GCF) were determined during rapid maxillary expansion (RME) treatment.Materials and methodsFourteen patients (10–13 years old) were included. A modified hyrax appliance was used for the treatment. After periodontal parameters were recorded, GCF was collected from the first molars at each observation [T1:baseline:14 days after periodontal prophylaxis and instructions; T2:1 day later hyrax inserted, at passive position; T3:1 week later; after the first activation; T4:after 2 × 1/4 activation; T5:after 7 × 1/4 activation; T6:after 14 × 1/4 activation; T7:retention period on the 1 st month; and T8:retention period on the 3rd month].ResultsAlthough the levels of IL1-β, NO, and PD increased significantly from T1 to T2, the GI, BOP%, and PI remained unchanged throughout treatment. GCF volume at buccal and palatal surfaces increased significantly from T1 to T4, T6, T7, and T8. The parameters in GCF and TAC levels were not only higher at palatal side in comparison with buccal, but also TOS levels increased at both buccal and palatal sides.ConclusionsIn this study, the differences of oxidative status and IL-1β levels during RME treatment could be attributable to orthopedic effect of the heavy forces on maxilla and minimal orthodontic forces on teeth applied by the RME apparatus.



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