Adenoid cystic carcinoma of head and neck: A retrospective clinical analysis of a single institution

Adenoid cystic carcinoma (ACC), first described by Billroth in 1856, was originally called cylindroma because of its histologic appearance [1]. ACC is a rare tumor, accounting for about 1% of head and neck tumors, but it is the most common malignancy of the minor salivary glands [2]. Characteristically, ACC progresses slowly, with wide perineural invasion; lymphatic spread to the neck is rare. Histologically, adenoid cystic carcinomas also arise in other sites in the head and neck field, such as the major salivary glands, the tracheobronchial tree, the esophagus, the lacrimal gland, and even sites outside the head and neck.

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