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Τρίτη 10 Απριλίου 2018

Development of DNA aptamers targeting low-molecular-weight amyloid-[small beta] peptide aggregates in vitro

Chem. Commun., 2018, Accepted Manuscript
DOI: 10.1039/C8CC02256A, Communication
Madhuri Chakravarty, Hadi AlShamaileh, He Huang, Rudi K Tannenberg,, Suxiang Chen, Simon Worrall, Peter R Dodd, Rakesh Naduvile Veedu
We have developed a novel functional nucleic acid aptamer to amyloid-[small beta] peptide 1-40 (A[small beta]1-40) and investigated its potential to detect A[small beta] peptide fragments in neuropathologically confirmed Alzheimer brain hippocampus tissues...
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