Lifelong CMV infection improves immune defense in old mice by broadening the mobilized TCR repertoire against third-party infection [Immunology and Inflammation]

Lifelong interactions between host and the ubiquitous and persistent cytomegalovirus (CMV) have been proposed to contribute to the age-related decline in immunity. Prior work from us and others found some support for that idea, yet evidence that this led to increased vulnerability to other infections was not obtained. Moreover, evidence...

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