BACKGROUND: Liver transplantation in children is often associated with coagulopathy and significant blood loss. Available data are limited. In this observational retrospective study, we assessed transfusion practices in pediatric patients undergoing liver transplantation at a single institution over the course of 9 years. METHODS: Data were retrospectively collected from patient medical records at the Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center. All patients who underwent liver transplantation from January 2008 to June 2017 were included. Primary and secondary outcomes were volume of red blood cells (RBCs) transfused and mortality, respectively. RESULTS: From January 2008 to June 2017, there were 278 liver transplants in 271 patients. The number of primary transplants were 259, second retransplants 15, and third retransplants 4. Average age at transplantation was 6.9 years. Biliary atresia, maple syrup urine disease, urea cycle defect, and liver tumor were the leading indications accounting for 66 (23.7%), 45 (16.2%), 24 (8.6%), and 23 (8.3%) of transplants, respectively. Seventy-six cases (27.3%) did not require RBC transfusions. Among those transfused, 181 (89.6%) of the cases required 12 months of age (0.12 BV). By diagnosis, the group requiring the highest median volume transfusion was patients with total parenteral nutrition–related liver failure (3.41 BV) followed by patients undergoing repeat transplants (0.6 BV). Comparison of primary versus repeat transplants shows a trend toward higher volume transfusions in third transplants (median, 2.71 BV), compared to second transplants (0.43 BV) and primary transplants (0.18 BV). Four of 271 patients (1.5%) died during admission involving liver transplantation. Nine of 271 patients (3.3%) died subsequently. Total mortality was 4.8%. CONCLUSIONS: In contrast to historically reported trends, evaluation of current transfusion practices reveals that most patients undergoing liver transplantation receive
https://ift.tt/2pCx3NW
Αρχειοθήκη ιστολογίου
-
►
2020
(289)
- ► Φεβρουαρίου (28)
-
►
2019
(9071)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3642)
- ► Ιανουαρίου (3200)
-
▼
2018
(39872)
- ► Δεκεμβρίου (3318)
-
▼
Οκτωβρίου
(3814)
-
▼
Οκτ 04
(150)
- Food‐induced fatal anaphylaxis: from epidemiologic...
- “So … who is your audience?”
- The division of cognitive labor: two missing dimen...
- Predictors of Therapeutic Outcome to Nucleotide Re...
- Classification of lesions inducing acquired choles...
- Bacteriology of peritonsillar abscess: the changin...
- Histopathological comparison of bone healing effec...
- Endoscopic observation of different repair pattern...
- Familial misophonia or selective sound sensitivity...
- Is there a best side for cochlear implants in post...
- Prognostic significance of soft tissue deposits in...
- Audiological and electrophysiological alterations ...
- Psychoacoustic classification of persistent tinnitus
- Disease‐specific quality of life after septoplasty...
- Association of Ugrp2 gene polymorphisms with adeno...
- Effects of cavity reconstruction on morbidity and ...
- Temporomandibular disorder: otologic implications ...
- Multidimensional effects of voice therapy in patie...
- Retro‐ and orthonasal olfactory function in relati...
- Diagnostic validity of methods for assessment of s...
- The use of tDCS as a therapeutic option for tinnit...
- Transoral robotic supraglottic partial laryngectom...
- Bilateral primary histiocytoid eccrine sweat gland...
- Stafne bone cavity containing ectopic parotid gland
- Thyroid® High-Impact Articles
- Real-Time Measurement of Xenon Concentration in a ...
- Predicting the Size of a Left Double-Lumen Tube fo...
- Regional Anesthesia and Readmission Rates After To...
- Predosing Chemical Stability of Admixtures of Prop...
- Resident Competency and Proficiency in Combined Sp...
- Red Blood Cell Transfusion in Pediatric Orthotopic...
- Statistical Versus Clinical Significance in Subcla...
- Lupin: An Emerging Food Allergen in the United States
- Sensitization Profiles to Hazelnut Allergens acros...
- Level of competence of primary and secondary schoo...
- Use of disposable blade for harvesting epidermal s...
- Late growth of infantile hemangiomas in children >...
- Two facets of sweat: A defensive factor in skin ti...
- Congenital cytomegalovirus infection inducing non-...
- Neurologically Acquired Laryngomalacia in a Pediat...
- Urine concentrations changes of cysteinyl leukotri...
- Trends in Sociodemographic Disparities of Pediatri...
- Corrigendum to 'Epidemiological characteristics of...
- Identification of Baseline Factors Associated With...
- The Role of Otolaryngologists in Eradicating Human...
- Cognitive Behavioral Therapy for Tinnitus Unbound
- The Role of Otolaryngologists in Eradicating Human...
- Effectiveness of Internet Cognitive Behavioral The...
- The 2018 American Head and Neck Society Presidenti...
- Interaction of Group B Streptococcus sialylated ca...
- Afatinib and Pembrolizumab for Head and Neck Squam...
- Aged complement factor H knockout mice kept in a c...
- Informal caregivers of people with an intellectual...
- Parents' and healthcare professionals' experiences...
- The Economics of Higher Education
- 9.4T MR microscopy of the substantia nigra with pa...
- Enhancing Behavior Change Technique Coding Methods...
- A direct method for the N-tetraalkylation of azama...
- LUBAC prevents lethal dermatitis by inhibiting cel...
- Data for "Low-noise 1.3 μm InAs/GaAs quantum dot l...
- Stafne bone cavity containing ectopic parotid gland
- Effects of cavity reconstruction on morbidity and ...
- Association of Ugrp2 gene polymorphisms with adeno...
- Disease-specific quality of life after septoplasty...
- Psychoacoustic classification of persistent tinnitus
- Audiological and electrophysiological alterations ...
- Prognostic significance of soft tissue deposits in...
- Is there a best side for cochlear implants in post...
- Familial misophonia or selective sound sensitivity...
- Endoscopic observation of different repair pattern...
- Histopathological comparison of bone healing effec...
- Bacteriology of peritonsillar abscess: the changin...
- Bilateral primary histiocytoid eccrine sweat gland...
- Retro- and orthonasal olfactory function in relati...
- Multidimensional effects of voice therapy in patie...
- Temporomandibular disorder: otologic implications ...
- Transoral robotic supraglottic partial laryngectom...
- Laryngeal inflammatory response to smoke and vape ...
- Microdeletion 22q11.2 syndrome: Does thymus incide...
- Osteoprotegerin mediate RANK/RANKL signaling inhib...
- Hypopharyngeal cancer: A state of the art review
- Patterns of failure, treatment outcomes and late t...
- Crosstalk between Raf-MEK-ERK and PI3K-Akt-GSK3β s...
- Shared genetic and epigenetic mechanisms between c...
- Label-free tissue proteomics can classify oral squ...
- Microbiological changes of the ageing oral cavity
- Novel method of fitting of children with auditory ...
- Epidemiology and Risk Factors of Asthma-COPD Overl...
- Impact of chronic rhinosinusitis on sleep: a contr...
- B cell lymphoma‐2‐like protein‐12 association with...
- Adoptive cell therapy of tolerogenic dendritic cel...
- Deficiency in interleukin‐10 production by M2 macr...
- Unsupervised cluster analysis of chronic rhinosinu...
- SNOT‐22 score patterns strongly negatively predict...
- Allergic rhinitis and the associated risk of noctu...
- Deletion of Nrf2 enhances susceptibility to eosino...
- Effects of mometasone furoate–impregnated biodegra...
- Ultrasound-guided lumbar plexus block using three ...
- Predictors for sustained new-onset atrial fibrilla...
- In vitro changes in the proportion of protein-unbo...
-
▼
Οκτ 04
(150)
- ► Σεπτεμβρίου (3683)
- ► Φεβρουαρίου (2693)
- ► Ιανουαρίου (3198)
-
►
2017
(41099)
- ► Δεκεμβρίου (3127)
- ► Σεπτεμβρίου (2173)
-
►
2016
(13807)
- ► Δεκεμβρίου (700)
- ► Σεπτεμβρίου (600)
- ► Φεβρουαρίου (1350)
- ► Ιανουαρίου (1400)
-
►
2015
(1500)
- ► Δεκεμβρίου (1450)
Ετικέτες
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου