Calciphylaxis in hemodialysed patients: Diagnostic value of calcifications in cutaneous biopsy

Abstract

Calciphylaxis or calcific uremia arteriopathy (CUA) is a rare and highly morbid condition that predominantly affects dialyzed end-stage renal disease (ESRD) patients¹. One-year survival rate is estimated to be 40-50%, with sepsis emerging as the leading cause of death ². Calciphylaxis presents with painful necrotic cutaneous ulcers, livedo racemosa, hemorrhagic patches, indurated plaques, or hemorrhagic bullae predominantly on the proximal lower extremities and trunk ².

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