Cells, Vol. 8, Pages 640: Defocused Image Changes Signaling of Ganglion Cells in the Mouse Retina Cells doi: 10.3390/cells8070640 Authors: Feng Pan Myopia is a substantial public health problem worldwide. Although it is known that defocused images alter eye growth and refraction, their effects on retinal ganglion cell (RGC) signaling that lead to either emmetropization or refractive errors have remained elusive. This study aimed to determine if defocused images had an effect on signaling...
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Cells, Vol. 8, Pages 639: Molecular Mechanisms of Microglial Motility: Changes in Ageing and Alzheimer’s Disease Cells doi: 10.3390/cells8060639 Authors: Diana K. Franco-Bocanegra Ciaran McAuley James A. R. Nicoll Delphine Boche Microglia are the tissue-resident immune cells of the central nervous system, where they constitute the first line of defense against any pathogens or injury. Microglia are highly motile cells and in order to carry out their function, they constantly...
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Cells, Vol. 8, Pages 637: Targeting the Oncogenic FGF-FGFR Axis in Gastric Carcinogenesis Cells doi: 10.3390/cells8060637 Authors: Jinglin Zhang Patrick M. K. Tang Yuhang Zhou Alfred S. L. Cheng Jun Yu Wei Kang Ka Fai To Gastric cancer (GC) is one of the most wide-spread malignancies in the world. The oncogenic role of signaling of fibroblast growing factors (FGFs) and their receptors (FGFRs) in gastric tumorigenesis has been gradually elucidated by recent studies....
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Cells, Vol. 8, Pages 638: The Multifunctional Sorting Protein PACS-2 Controls Mitophagosome Formation in Human Vascular Smooth Muscle Cells through Mitochondria-ER Contact Sites Cells doi: 10.3390/cells8060638 Authors: Manon Moulis Elisa Grousset Julien Faccini Kevin Richetin Gary Thomas Cecile Vindis Mitochondria-associated ER membranes (MAMs) are crucial for lipid transport and synthesis, calcium exchange, and mitochondrial functions, and they also act as signaling platforms....
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Cells, Vol. 8, Pages 636: BMP2 and TGF-β Cooperate Differently during Synovial-Derived Stem-Cell Chondrogenesis in a Dexamethasone-Dependent Manner Cells doi: 10.3390/cells8060636 Authors: Nikolas Kovermann Valentina Basoli Elena Della Bella Mauro Alini Christoph Lischer Hagen Schmal Eva Kubosch Martin Stoddart Recent studies highlighting mesenchymal stem cell (MSC) epigenetic memory suggest that a different differentiation medium may be required depending on the...
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Cells, Vol. 8, Pages 635: Activation of Slit2/Robo1 Signaling Promotes Tumor Metastasis in Colorectal Carcinoma through Activation of the TGF-β/Smads Pathway Cells doi: 10.3390/cells8060635 Authors: Yuying Yao Zijun Zhou Liuyou Li Junchen Li Lixun Huang Jiangchao Li Cuiling Qi Lingyun Zheng Lijing Wang Qian-Qian Zhang Slit2 (slit guidance ligand 2), a ligand of the Roundabout1 (Robo1) transmembrane receptor, is often overexpressed in colorectal carcinomas (CRCs)....
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Cells, Vol. 8, Pages 634: Relationship between Multiple Sclerosis-Associated IL2RA Risk Allele Variants and Circulating T Cell Phenotypes in Healthy Genotype-Selected Controls Cells doi: 10.3390/cells8060634 Authors: Sophie Buhelt Helle Bach Søndergaard Annette Oturai Henrik Ullum Marina Rode von Essen Finn Sellebjerg Single nucleotide polymorphisms (SNPs) in or near the IL2RA gene, that encodes the interleukin-2 (IL-2) receptor α (CD25), are associated with...
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