Targeted Therapy and Traditional Chemotherapy in Melanoma and Cutaneous Squamous Cell Carcinoma. Facial Plast Surg. 2020 Apr;36(2):186-193 Authors: Ma VT, Haring CT, Warrier G, Swiecicki PL Abstract Cutaneous squamous cell carcinoma (cSCC) and melanoma encompass the majority of all malignant skin cancers. There has been an increase in their incidence globally in recent decades. In cases of high-risk, unresectable, or metastatic disease; or when patient...
Sat May 16, 2020 13:19
Management of Complications from Skin Cancer Reconstruction. Facial Plast Surg. 2020 Apr;36(2):176-179 Authors: Vila PM, Thomas JR Abstract Reconstruction of facial cutaneous defects from skin cancer surgery is a commonly done procedure in the hands of many facial plastic surgeons. Excellent surgical technique should always be employed to reduce the risk of a poor result. However, complications do occur and can be devastating for both the patient...
Sat May 16, 2020 13:19
Management of Complicated Nasal Defects. Facial Plast Surg. 2020 Apr;36(2):158-165 Authors: Owusu J, Nesbitt B, Boahene K Abstract The nose is the most common site for nonmelanoma skin cancer. Fortunately, most skin cancer lesions on the nose are discovered early and their timely diagnosis and excision result in superficial defects that can be reconstructed with minimal impact on the aesthetics and function. Reconstruction of full-thickness defects...
Sat May 16, 2020 13:19
Management of Large Facial Defects. Facial Plast Surg. 2020 Apr;36(2):148-157 Authors: Rabbani CC, Hwang MS, Byrne PJ, Desai SC Abstract There is considerable variation in the surgical management of patients with large facial defects after excision of skin malignancy. The surrounding facial subunits as well as local, regional, and distant soft-tissue flaps can be considered in more complicated facial defects. We place an emphasis on the versatility...
Sat May 16, 2020 13:19
High-Risk Nonmelanoma Skin Cancers: Identification, Management, and Reconstruction. Facial Plast Surg. 2020 Apr;36(2):141-147 Authors: Misch ES, Terella AM Abstract High-risk nonmelanoma skin cancers of the head and neck may be identified through a variety of tumor risk factors, including location on the lips or ears, size > 2 cm, recurrence, patient immunocompromised status, poor tumor differentiation, > 6 mm thickness, Clark level V depth...
Sat May 16, 2020 13:19
Management of Melanoma and Advanced Non-Melanoma Skin Cancers of the Face. Facial Plast Surg. 2020 Apr;36(2):131-132 Authors: Moyer JS PMID: 32413919 [PubMed - as supplied by publisher]
Sat May 16, 2020 13:19
Clinical outcomes of head and neck adenoid cystic carcinoma patients treated with pencil beam-scanning proton therapy. Oral Oncol. 2020 May 12;107:104752 Authors: Pelak MJ, Walser M, Bachtiary B, Hrbacek J, Lomax AJ, Kliebsch UL, Beer J, Pica A, Malyapa R, Weber DC Abstract OBJECTIVE: The aim of this study was to evaluate the outcome of patients with head and neck adenoid cystic carcinoma (ACC) treated using pencil beam scanning proton therapy (PBS...
Sat May 16, 2020 13:19
Factors affecting complications and comorbidities in children with cholesteatoma. Int J Pediatr Otorhinolaryngol. 2020 May 06;135:110080 Authors: Lee JA, Fuller SR, Nguyen SA, Meyer TA Abstract OBJECTIVE: To evaluate the effects of age, race, payer status, and socioeconomic status on complications and comorbidities in children with cholesteatoma. METHODS: An analysis of the Kids' Inpatient Database was performed on cases of cholesteatoma...
Sat May 16, 2020 13:19
High p16INK4a immunoexpression is not HPV dependent in oral leukoplakia. Arch Oral Biol. 2020 May 04;115:104738 Authors: Tomo S, Biss SP, Crivelini MM, de Oliveira SHP, Biasoli ÉR, Tjioe KC, Bernabé DG, Villa LL, Miyahara GI Abstract OBJECTIVE: To evaluate the prevalence of HPV DNA detection in fresh tissue from oral leukoplakia by Linear Array assay, and its correlation with p16INK4a immunoexpression in the northwest region of the São Paulo state,...
Sat May 16, 2020 13:19
Epithelial-to-mesenchymal transition is a prognostic marker for patient outcome in advanced stage HNSCC patients treated with chemoradiotherapy. Radiother Oncol. 2020 May 12;: Authors: van der Heijden M, Essers PBM, Verhagen CVM, Willems SM, Sanders J, de Roest RH, Vossen DM, Leemans CR, Verheij M, Brakenhoff RH, van den Brekel MWM, Vens C Abstract BACKGROUND: The prognosis of patients with HPV-negative advanced stage head and neck squamous cell...
Sat May 16, 2020 13:19
The French world premiere of transoral robotic surgery for pituitary tumors with the Da Vinci apparatus: promises and pitfalls. Neurochirurgie. 2020 May 12;: Authors: Chauvet D, Lot G, Hans S PMID: 32413371 [PubMed - as supplied by publisher]
Sat May 16, 2020 13:19
Golgi Apparatus: An Emerging Platform for Innate Immunity. Trends Cell Biol. 2020 Jun;30(6):467-477 Authors: Tao Y, Yang Y, Zhou R, Gong T Abstract The Golgi apparatus serves as a receiving station where proteins from the endoplasmic reticulum (ER) are further processed before being sent to other cellular compartments. In addition to its well-appreciated roles in vesicular trafficking and protein/lipid secretion, recent studies have demonstrated...
Sat May 16, 2020 13:19
The opposite functions of miR-24 in the osteogenesis and adipogenesis of adipose-derived mesenchymal stem cells are mediated by the HOXB7/β-catenin complex. FASEB J. 2020 May 15;: Authors: Liu Z, Deng Y, Li T, Zhu F, Zhou X, He Y Abstract Adipose-derived mesenchymal stem cells (ADMSCs) used in combination with nanoparticles or scaffolds represent promising candidates for bone engineering. Compared to bone marrow-derived MSCs (BMMSCs), ADMSCs show...
Sat May 16, 2020 13:19
Comparison of Clinical Characteristics and Magnetic Resonance Imaging of Salivary Glands With Magnetic Resonance Sialography in Sjögren's Syndrome. Laryngoscope. 2020 May 15;: Authors: André R, Becker M, Lombardi T, Buchholzer S, Marchal F, Seebach JD Abstract OBJECTIVES/HYPOTHESIS: To compare the results of magnetic resonance imaging with magnetic resonance sialography (MRSIAL) and the clinical and laboratory characteristics in a well-characterized...
Sat May 16, 2020 13:19
Age Is Associated With Pain Experience and Opioid Use After Head and Neck Free Flap Reconstruction. Laryngoscope. 2020 May 15;: Authors: Rettig EM, Janus JR, Moore EJ, Price DL, Glasgow AE, Marinelli JP, Habermann EB, Van Abel KM Abstract OBJECTIVES: To describe pain experience and opioid use after major head and neck reconstructive surgery. STUDY DESIGN: Retrospective cohort study. METHODS: Patients undergoing major head and...
Sat May 16, 2020 13:19
Ventilatory support in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: a systematic review and meta-analysis. J Dermatolog Treat. 2020 May 15;:1-17 Authors: Phan K, Oh LJ, Issler-Fisher A, Rao A, Wong EH, Maitz P Abstract Introduction: Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are blistering cutaneous disorders that often manifest with epidermal and mucosal necrosis. In extreme cases, the upper or bronchial airways...
Sat May 16, 2020 13:19
IN RESPONSE TO THE LETTER TO THE EDITOR: AGE-RELATED HEARING LOSS IS STRONGLY ASSOCIATED WITH COGNITIVE DECLINE REGARDLESS OF THE APOE4 POLYMORPHISM. Otol Neurotol. 2020 Jun;41(5):718-719 Authors: Morita Y, Sasaki T, Takahashi K, Kitazawa M, Nonomura Y, Yagi C, Yamagishi T, Ohshima S, Izumi S, Horii A, Wakasugi M, Yokoseki A, Narita I, Endo N PMID: 32412726 [PubMed - as supplied by publisher]
Sat May 16, 2020 13:19
Fluorescence imaging-guided multifunctional liposomes for tumor-specific phototherapy for laryngeal carcinoma. Biomater Sci. 2020 May 15;: Authors: Wu D, Zhao Z, Wang N, Zhang X, Yan H, Chen X, Fan Y, Liu W, Liu X Abstract Reliable diagnosis and efficient targeted therapy are important and may lead to the effective treatment of laryngeal carcinoma. Multifunctional nano-theranostic agents demonstrate great potential in tumor theranostic applications....
Sat May 16, 2020 13:19
[Multicystic transformation of the post-radiation necrosis zone of the brain. A case report and literature review]. Zh Vopr Neirokhir Im N N Burdenko. 2020;84(2):72-82 Authors: Kosyrkova AV, Goryainov SA, Kravchuk AD, Golanov AV, Maryashev SA, Vetlova ER, Antipina NA, Pronin IN, Batalov AI, Zakharova NE, Potapov AA Abstract Post-radiation cyst of the brain is a rare complication that often arises many years after irradiation for head and neck neoplasms....
Sat May 16, 2020 13:19
Analyzing the prognostic value of DKK1 expression in human cancers based on bioinformatics. Ann Transl Med. 2020 Apr;8(8):552 Authors: Wei R, Rodrìguez RA, Mullor MDMR, Tan Z, Gui Y, Hu J, Zhu T, Huang X, Zhu Y, Xu J Abstract Background: The Dickkopf1 (DKK1) gene encodes a protein that belongs to the Dickkopf family. The protein can inhibit the Wnt signaling pathway which plays a key role in the carcinogenesis and progression of various types of...
Sat May 16, 2020 13:19
Considerations for the Management and Triage of Ocular Oncology Cases during the COVID-19 Pandemic. Ocul Oncol Pathol. 2020 Apr 21;6(3):1-4 Authors: Skalet AH, Allen RC, Shields CL, Wilson MW, Mruthyunjaya P, Gombos DS PMID: 32411697 [PubMed]
Sat May 16, 2020 13:19
Activation PDGFR-α/AKT Mediated Signaling Pathways in Oral Squamous Cell Carcinoma by Mesenchymal Stem/Stromal Cells Promotes Anti-apoptosis and Decreased Sensitivity to Cisplatin. Front Oncol. 2020;10:552 Authors: Wang J, Cui R, Clement CG, Nawgiri R, Powell DW, Pinchuk IV, Watts TL Abstract Desmoplasia, a hallmark of a head and neck cancer, has both biologic and physiologic effects on cancer progression and chemotherapeutic response. Mesenchymal...
Sat May 16, 2020 13:19
Nasal endoscopy protocols in the era of COVID-19. World J Otorhinolaryngol Head Neck Surg. 2020 May 14;: Authors: Fried J, Imam SA, Lee JA, Nguyen SA PMID: 32411495 [PubMed - as supplied by publisher]
Sat May 16, 2020 13:19
Differential Diagnostic Reasoning Method for Benign Paroxysmal Positional Vertigo Based on Dynamic Uncertain Causality Graph. Comput Math Methods Med. 2020;2020:1541989 Authors: Dong C, Wang Y, Zhou J, Zhang Q, Wang N Abstract The accurate differentiation of the subtypes of benign paroxysmal positional vertigo (BPPV) can significantly improve the efficacy of repositioning maneuver in its treatment and thus reduce unnecessary clinical tests and inappropriate...
Sat May 16, 2020 13:19
Methotrexate-Associated Lymphoproliferative Disorder Developed Ectopically in the Maxillary Gingiva and Bilateral Lungs. Case Rep Med. 2020;2020:4814519 Authors: Obata K, Okui T, Kishimoto K, Ibaragi S, Sasaki A Abstract A 58-year-old Japanese woman complained of a painful right maxillary premolar gingiva and ulcer. The patient had RA and had been treated with several immunosuppressive drugs such as methotrexate. Head and neck CT indicated no obvious...
Sat May 16, 2020 13:19
Feasibility of Attachable Ring Stimulator for Intraoperative Neuromonitoring during Thyroid Surgery.
Feasibility of Attachable Ring Stimulator for Intraoperative Neuromonitoring during Thyroid Surgery. Int J Endocrinol. 2020;2020:5280939 Authors: Kim J, Moon HJ, Chai YJ, Lee JM, Hwang KT, Wu CW, Dionigi G, Kim HY, Park KS, Kim SW, Yi KH Abstract Objective: Stimulator-attached dissecting instruments are useful for intraoperative nerve monitoring during thyroidectomy. The aim of this study was to evaluate the feasibility of an attachable ring stimulator...
Sat May 16, 2020 13:19
The Prognostic Signature and Potential Target Genes of Six Long Non-coding RNA in Laryngeal Squamous Cell Carcinoma. Front Genet. 2020;11:413 Authors: Gong S, Xu M, Zhang Y, Shan Y, Zhang H Abstract Studies have shown that long non-coding RNA (lncRNA) may act as the carcinogenic factor or tumor suppressor of laryngeal squamous cell carcinoma (LSCC). This study aims to identify the prognostic value and potential target protein-coding genes (PCGs)...
Sat May 16, 2020 13:19
Variability in Medullary Thyroid Carcinoma in RET L790F Carriers: A Case Comparison Study of Index Patients. Front Endocrinol (Lausanne). 2020;11:251 Authors: Mathiesen JS, Nielsen SG, Rasmussen ÅK, Kiss K, Wadt K, Hermann AP, Nielsen MF, Larsen SR, Brusgaard K, Frederiksen AL, Godballe C, Rossing M Abstract Background: Previous studies have suggested that the variability in age of onset and aggressiveness of medullary thyroid carcinoma (MTC) in...
Sat May 16, 2020 13:19
The Effect of Side of Implantation on the Cortical Processing of Frequency Changes in Adult Cochlear Implant Users. Front Neurosci. 2020;14:368 Authors: Liang C, Wenstrup LH, Samy RN, Xiang J, Zhang F Abstract Cochlear implants (CI) are widely used in children and adults to restore hearing function. However, CI outcomes are vary widely. The affected factors have not been well understood. It is well known that the right and left hemispheres play different...
Sat May 16, 2020 13:19
Managing locally advanced adenoid cystic carcinoma of the head and neck during the COVID-19 pandemic crisis: is this the right time for particle therapy? Oral Oncol. 2020 May 14;:104803 Authors: S R, B V, B B, A B, L L, P C, P N, C P, M A, M B, E O PMID: 32410826 [PubMed - as supplied by publisher]
Sat May 16, 2020 13:19
Covid19 pandemic; A practicing head and neck surgeon's perspective of an institutional model. Oral Oncol. 2020 May 14;:104765 Authors: Varghese BT Abstract •Surgery for Mucosal Head and neck Cancers needs special consideration as they are AGP, placing the OT staff at a major risk.•Nevertheless all such procedures are considered semi emergencies and they cannot be postponed indefinitely.•Support Machinery of the Government and the co-operation of...
Sat May 16, 2020 13:19
The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC): A report of 2,781 cases in a Chinese population. Chin J Cancer Res. 2020 Apr;32(2):140-148 Authors: Zhu Y, Song Y, Xu G, Fan Z, Ren W Abstract Objective: To evaluate the diagnostic utility of The Bethesda System for Reporting Thyroid Cytology (TBSRTC) at Peking University Cancer Hospital, the incidence of noninvasive follicular thyroid neoplasms with papillary-like nuclear features...
Sat May 16, 2020 13:19
Intraoperative radiotherapy with low energy x-rays for primary and recurrent soft-tissue sarcomas. Radiat Oncol. 2020 May 14;15(1):110 Authors: Sarria GR, Petrova V, Wenz F, Abo-Madyan Y, Sperk E, Giordano FA Abstract BACKGROUND: Soft tissue sarcomas (STS) treatment remains a therapeutic challenge. Intraoperative radiotherapy (IORT) resembles a safe and efficient for STS treatment. The first data on electronic-IORT (eIORT) using low-energy photons...
Sat May 16, 2020 13:19
Single-center versus multi-center data sets for molecular prognostic modeling: a simulation study. Radiat Oncol. 2020 May 14;15(1):109 Authors: Samaga D, Hornung R, Braselmann H, Hess J, Zitzelsberger H, Belka C, Boulesteix AL, Unger K Abstract BACKGROUND: Prognostic models based on high-dimensional omics data generated from clinical patient samples, such as tumor tissues or biopsies, are increasingly used for prognosis of radio-therapeutic success....
Sat May 16, 2020 13:19
Smell and taste alterations in Covid-19: a cross-sectional analysis of different cohorts. Int Forum Allergy Rhinol. 2020 May 14;: Authors: Paderno A, Schreiber A, Grammatica A, Raffetti E, Tomasoni M, Gualtieri T, Taboni S, Zorzi S, Lombardi D, Deganello A, Redaelli De Zinis LO, Maroldi R, Mattavelli D Abstract BACKGROUND: Olfactory (OD) and gustatory (GD) dysfunction have been proven to be a typical symptom of SARS-CoV-2 infection. However, their...
Sat May 16, 2020 13:19
An Electrochemical Non-Enzymatic Glucose Sensor Based on Ultrathin PdAg Single-Crystalline Nanowires. Chempluschem. 2020 May;85(5):970-976 Authors: Xu X, Lv H, Sun L, Song P, Liu B, Chen X Abstract Electrochemical non-enzymatic sensors have great potential for prompt and efficient detection of glucose. Herein, a novel, highly efficient electrochemical non-enzymatic glucose sensor is reported that is based on ultrathin PdAg single-crystalline nanowires...
Sat May 16, 2020 13:19
Pilot Study of Quantitative Methods for Differentiating Pharyngeal Swallowing Mechanics by Dysphagia Etiology. Dysphagia. 2020 May 14;: Authors: Tadavarthi Y, Hosseini P, Reyes SE, Focht Garand KL, Pisegna JM, Pearson WG Abstract Quantitative analysis of modified barium swallow (MBS) imaging is useful to determine the impact of various disease states on pharyngeal swallowing mechanics. In this retrospective proof of concept study, kinematic analysis...
Sat May 16, 2020 13:19
The Effect of Cranial Nerve Stimulation on Swallowing: A Systematic Review. Dysphagia. 2020 May 14;: Authors: Florie MGMH, Pilz W, Dijkman RH, Kremer B, Wiersma A, Winkens B, Baijens LWJ Abstract This systematic review summarizes published studies on the effect of cranial nerve stimulation (CNS) on swallowing and determines the level of evidence of the included studies to guide the development of future research on new treatment strategies for oropharyngeal...
Sat May 16, 2020 13:19
Swallowing in Obese Individuals before and after Bariatric Surgery. Obes Surg. 2020 May 14;: Authors: Parreira LC, Salgado-Junior W, Dantas RO Abstract PURPOSE: To evaluate the oral and pharyngeal phases of swallowing in obese patients before and after bariatric surgery. MATERIAL AND METHOD: Swallowing was evaluated by videofluoroscopy before and after 80 to 123 days from bariatric surgery in 19 individuals with obesity (15 women), aged...
Sat May 16, 2020 13:19
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