Related ArticlesACCELERATE and European Medicine Agency Paediatric Strategy Forum for medicinal product development for mature B-cell malignancies in children. Eur J Cancer. 2019 03;110:74-85 Authors: Pearson ADJ, Scobie N, Norga K, Ligas F, Chiodin D, Burke A, Minard-Colin V, Adamson P, Marshall LV, Balakumaran A, Benettaib B, Bhargava P, Bollard CM, Bolotin E, Bomken S, Buechner J, Burkhardt B, Caron H, Copland C, Demolis P, Egorov A, Farhan M, Zugmaier G, Gross T,...
Sat May 16, 2020 13:16
Related ArticlesPrevalence and reproductive manifestations of macroprolactinemia. Endocrine. 2019 02;63(2):332-340 Authors: Kalsi AK, Halder A, Jain M, Chaturvedi PK, Sharma JB Abstract PURPOSE: Macroprolactinemia is characterized by predominance of macroprolactin molecules in circulation and generally has extra-pituitary origin. Macroprolactin is viewed as biologically inactive, therefore asymptomatic, and thus may not require any treatment or prolonged...
Sat May 16, 2020 13:16
Related ArticlesT2-weighted magnetic resonance imaging characterization of prolactinomas and association with their response to dopamine agonists. Endocrine. 2019 02;63(2):323-331 Authors: Burlacu MC, Maiter D, Duprez T, Delgrange E Abstract PURPOSE: Recent work supports the use of T2-weighted MRI intensity as a tool for treatment stratification in acromegaly. Our study aimed to establish if the pattern of T2 intensity could be a predictor of hormonal...
Sat May 16, 2020 13:16
Adenoid Cystic Carcinoma of Bartholin's Gland: What Is the Best Approach? Oncology. 2020 May 14;:1-7 Authors: Barcellini A, Gadducci A, Laliscia C, Imparato S, Vitolo V, Preda L, Valvo F Abstract Background and summary: Among all vulvar cancers, primary adenoid cystic carcinoma (ACC) of Bartholin's gland is a very rare tumor characterized by a slow growth, a high local aggressiveness, and a remarkable recurrence rate. Due to its rarity, treatment remains...
Fri May 15, 2020 13:07
Coexistence of DIPNECH and carotid body paraganglioma: is it just a coincidence? Endocrinol Diabetes Metab Case Rep. 2020 May 13;2020: Authors: Pedro J, Cunha FM, Neto V, Hespanhol V, Martins DF, Guimarães S, Varela A, Carvalho D Abstract Summary: We describe the case of a 56 year-old woman with the almost simultaneous appearance of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) and a carotid body paraganglioma. Of interest, 6...
Fri May 15, 2020 13:07
First ever case report of co-occurrence of hobnail variant of papillary thyroid carcinoma and intrathyroid parathyroid adenoma in the same thyroid lobe. Int J Surg Case Rep. 2020 May 05;70:40-52 Authors: Al-Yahri O, Abdelaal A, El Ansari W, Farghaly H, Murshed K, Zirie MA, Al Hassan MS Abstract INTRODUCTION: The hobnail variant of papillary thyroid cancer (PTC) is rare. Intrathyroid parathyroid adenoma (ITPA) is also rare. Co-ocurrence of PTC and ITPA...
Fri May 15, 2020 13:07
Plitidepsin to treat multiple myeloma. Drugs Today (Barc). 2020 May;56(5):337-347 Authors: Gomes NGM, Valentão P, Andrade PB, Pereira RB Abstract While remaining relatively rare, multiple myeloma (MM) accounts for approximately 10% of all hematological malignancies, being an insidious disease with an overall 5-year survival rate of 52%. In addition to other associated complications, myeloma bone disease further aggravates MM patients, the majority of...
Fri May 15, 2020 13:07
Biallelic NF1 inactivation in high grade serous ovarian cancers from patients with neurofibromatosis type 1. Fam Cancer. 2020 May 13;: Authors: Courtney E, Chan SH, Li ST, Ishak D, Merchant K, Shaw T, Chay WY, Chin FHX, Wong WL, Wong A, Ngeow J Abstract Neurofibromatosis type 1 (NF1) is a multisystem disorder caused by germline heterozygous NF1 loss-of-function variants. The NF1 gene encodes neurofibromin, a RAS GTPase-activating protein, which functions...
Fri May 15, 2020 13:07
Chronic Use of Long-Acting Somatostatin Analogues (SSAs) and Exocrine Pancreatic Insufficiency (EPI) in Patients with Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs): An Under-recognized Adverse Effect. Cancer Med J. 2020;3(2):75-84 Authors: Wasif Saif M, Romano A, Smith MH, Patel R, Relias V Abstract Background: Somatostatin Analogues (SSAs) are used to treat Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and acromegaly. Side effects...
Fri May 15, 2020 13:07
An application of ERBB2 receptor inhibitors in a rare case of S310F somatic ERBB2 mutation of primary signet-ring cell adenocarcinoma of vagina: A case report and review literature of S310F somatic ERBB2 mutation in breast and gynecologic cancers. Gynecol Oncol Rep. 2020 May;32:100577 Authors: Hou JY, Wright JD, Achariyapota V Abstract •The extremely uncommon subtype of epithelial vaginal cancer.•Comprehensive genomic sequencing of the rare subtype vaginal...
Fri May 15, 2020 13:07
Circulating microRNAs: Next-generation Cancer Detection. Keio J Med. 2020 May 13;: Authors: Matsuzaki J, Ochiya T Abstract Early detection of cancer is crucial for its ultimate control and the prevention of malignant progression. In Japan, a nationwide project was conducted between 2014 and 2019 to develop novel cancer detection tools using serum microRNAs (miRNAs). Using the National Cancer Center Biobank, we collected more than 10,000 serum samples...
Fri May 15, 2020 13:07
Related Articles[Bilateral occlusion of retinal vessels in Waldenstrom's disease (a case study)]. Vestn Oftalmol. 2020;136(1):90-96 Authors: Neroev VV, Kiseleva TN, Okhotsimskaya TD, Eliseeva EK, Ryabina MV, Vasilchenko VV Abstract The article describes a clinical case of bilateral occlusion of retinal vessels in a patient with Waldenstrom's disease - a rare lymphoplasmocytic tumor of the bone marrow characterized by a complex of syndromes, among which...
Fri May 15, 2020 13:07
Related ArticlesTRK inhibition in soft tissue sarcomas: A comprehensive review. Semin Oncol. 2020 02;47(1):73-84 Authors: Assi T, Rassy E, Nassereddine H, Farhat F, Karak FE, Kattan J, Ghosn M Abstract Soft-tissue sarcomas (STS) are a group of rare mesenchymal tumors that constitutes ∼1% of all solid tumors. It remains a rare tumor which lacks effective treatment options. Precision oncology may be of interest in this regard by identifying potential...
Fri May 15, 2020 13:07
Related ArticlesAntimicrobial utilization and antimicrobial resistance in patients with haematological malignancies in Japan: a multi-centre cross-sectional study. Ann Clin Microbiol Antimicrob. 2020 Feb 17;19(1):7 Authors: Mimura W, Fukuda H, Akazawa M Abstract BACKGROUND: Infection is a major complication for patients with haematological malignancies. It is important to better understand the use of antimicrobial agents and antibiotic resistance for...
Fri May 15, 2020 13:07
Related ArticlesLife-threatening Hypercalcemia as the First Manifestation of Acute Lymphoblastic Leukemia. Indian Pediatr. 2019 11 15;56(11):972-974 Authors: Roy K, Sharma R, Jana M, Jain V Abstract Hypercalcemia of malignancy, usually reported in adults in advanced stages, is rare in children. A 4-year-old boy presented with intermittent episodes of severe hypercalcemia, which improved with intravenous hydration therapy, furosemide and bisphosphonates...
Fri May 15, 2020 13:07
Related ArticlesPrimary Ewing sarcoma of the larynx with distant metastasis: a case report and review of the literature. Curr Oncol. 2019 08;26(4):e574-e577 Authors: Maroun CA, Khalifeh I, Tfayli A, Moukarbel RV Abstract Extraosseous Ewing sarcoma is a rare, poorly differentiated round-cell tumour that is part of the Ewing sarcoma family of tumours. Here, we present an extremely rare case of primary extraosseous Ewing sarcoma arising in the larynx,...
Fri May 15, 2020 13:07
Related Articles18 F-Fluorodeoxyglucose positron-emission tomography for the investigation of malignancy in patients with suspected paraneoplastic neurologic syndromes and negative or indeterminate conventional imaging: a retrospective analysis of the Ontario PET Access Program, with systematic review and meta-analysis. Curr Oncol. 2019 08;26(4):e458-e465 Authors: Harlos C, Metser U, Poon R, MacCrostie P, Mason W Abstract Objective: Paraneoplastic neurologic...
Fri May 15, 2020 13:07
Related ArticlesSpecies-Specific Quantitative Proteomics Profiles of Sarcoma Patient-Derived Models Closely Reflect Their Primary Tumors. Proteomics Clin Appl. 2019 11;13(6):e1900054 Authors: Shiozawa K, Oyama R, Takahashi M, Kito F, Hattori E, Yoshida A, Kawai A, Ono M, Kondo T Abstract PURPOSE: The purpose is to examine whether patient-derived sarcoma models recapitulate the spectrum of sarcoma heterogeneity seen in patients. EXPERIMENTAL...
Fri May 15, 2020 13:07
Related ArticlesBeyond satisfaction scores: exploring emotionally adverse patient experiences. Am J Manag Care. 2019 05 01;25(5):e145-e152 Authors: Holdsworth LM, Zionts DL, De Sola-Smith KM, Valentine M, Winget MD, Asch SM Abstract OBJECTIVES: Although improving the average patient experience is at the center of recent efforts to make cancer care more patient centered, extreme experiences may be more informative for quality improvement. Little is known...
Fri May 15, 2020 13:07
Related ArticlesLong term control and preservation of renal function after multiple courses of stereotactic body radiation therapy for renal cell carcinoma. Can J Urol. 2019 04;26(2):9743-9745 Authors: Reddy AV, Mills MN, Liauw SL, Baliga S, Kersh CR Abstract Renal cell carcinoma (RCC) is usually treated with surgery, with or without systemic therapy. For select patients, stereotactic body radiation therapy (SBRT) may be a suitable alternative. Although...
Fri May 15, 2020 13:07
Related ArticlesFollicular cholecystitis: clinicopathologic associations. Hum Pathol. 2019 06;88:1-6 Authors: Salari B, Rezaee N, Toland A, Chatterjee D Abstract Follicular cholecystitis (FC) is a relatively rare entity with uncertain causal associations. In this study, we aimed to explore different clinicopathologic associations of FC, and to better characterize the entity. A retrospective review of archival hematoxylin and eosin slides and pertinent...
Fri May 15, 2020 13:07
Related ArticlesThe repertoire of genetic alterations in salivary duct carcinoma including a novel HNRNPH3-ALK rearrangement. Hum Pathol. 2019 06;88:66-77 Authors: Dogan S, Ng CKY, Xu B, Kumar R, Wang L, Edelweiss M, Scott SN, Zehir A, Drilon A, Morris LGT, Lee NY, Antonescu CR, Ho AL, Katabi N, Berger MF, Reis-Filho JS Abstract Salivary duct carcinoma (SDC) is a rare, aggressive malignancy with limited treatment options and poor outcome. Twenty-nine...
Fri May 15, 2020 13:07
Related ArticlesFrequent loss of heterozygosity of SMAD4 locus and prognostic impacts of SMAD4 immunohistochemistry in gastric adenocarcinoma with enteroblastic differentiation. Hum Pathol. 2019 06;88:18-26 Authors: Yatagai N, Saito T, Akazawa Y, Hayashi T, Yanai Y, Tsuyama S, Murakami T, Ueyama H, Watanabe S, Nagahara A, Yao T Abstract Gastric adenocarcinoma with enteroblastic differentiation (GAED) is a rare variant of gastric adenocarcinoma. Clinicopathologically,...
Fri May 15, 2020 13:07
Related Articles[Gastric bronchogenic cysts. An unusual location]. Rev Esp Patol. 2019 Apr - Jun;52(2):117-119 Authors: Ruiz Molina I, Landauro Comesaña C, Solís García E, Cívico Amat V, Sánchez Quintana F Abstract Bronchogenic cysts are rare benign lesions that arise during embryogenesis of the primitive proximal intestine and are located primarily in the lung. They are lined with cuboid or columnar pseudostratified and ciliated epithelium and have...
Fri May 15, 2020 13:07
Related ArticlesCareful investigation of a rare disease: insights into multiple endocrine neoplasia type 2B. Lancet Diabetes Endocrinol. 2019 03;7(3):167-168 Authors: Lodish MB PMID: 30660596 [PubMed - indexed for MEDLINE]
Fri May 15, 2020 13:07
Related ArticlesPerioperative Care of Children Undergoing Intra-arterial Chemotherapy for Retinoblastoma. J Perianesth Nurs. 2019 Jun;34(3):476-482 Authors: Almontaser E, Ritchie C, Madison J, Jabbour P Abstract Retinoblastoma (RB) is a rare cancer of the eye, most commonly seen in children. Intra-arterial chemotherapy for RB is a relatively new treatment modality that has gained increasing popularity worldwide. The principal underlying the intra-arterial...
Fri May 15, 2020 13:07
Related ArticlesNiemann-Pick Disease Type B: A Rare Cause of Lung Cysts. Arch Bronconeumol. 2019 02;55(2):100 Authors: Gorospe L, Chinea-Rodríguez A, Villarrubia-Espinosa J, Arrieta P PMID: 30025906 [PubMed - indexed for MEDLINE]
Fri May 15, 2020 13:07
Related ArticlesClinical Manifestations and Outcomes of Patients with Sarcomatoid Hepatocellular Carcinoma. Hepatology. 2019 01;69(1):209-221 Authors: Liao SH, Su TH, Jeng YM, Liang PC, Chen DS, Chen CH, Kao JH Abstract Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading cause of cancer-related deaths worldwide. Sarcomatoid HCC is a rare histological subtype of HCC with largely unclear clinical manifestations and outcomes....
Fri May 15, 2020 13:07
Related ArticlesPulmonary Necrobiotic Nodules: A Rare Manifestation of Crohn's Disease. Arch Bronconeumol. 2019 02;55(2):108-110 Authors: Larrey Ruiz L, Sabater Abad C, Peño Muñoz L, Huguet Malavés JM, Juan Samper G PMID: 29884425 [PubMed - indexed for MEDLINE]
Fri May 15, 2020 13:07
Related ArticlesHead and neck cancer patient images for determining auto-segmentation accuracy in T2-weighted magnetic resonance imaging through expert manual segmentations. Med Phys. 2020 Jun;47(5):2317-2322 Authors: Cardenas CE, Mohamed ASR, Yang J, Gooding M, Veeraraghavan H, Kalpathy-Cramer J, Ng SP, Ding Y, Wang J, Lai SY, Fuller CD, Sharp G Abstract PURPOSE: The use of magnetic resonance imaging (MRI) in radiotherapy treatment planning has...
Mon May 18, 2020 14:34
Related ArticlesSubglottic plasma cell mucositis: a case study highlighting challenge in management. ANZ J Surg. 2020 May 17;: Authors: Kristensen H, Lam M, MacKay S PMID: 32418313 [PubMed - as supplied by publisher]
Mon May 18, 2020 14:34
Related ArticlesEvaluating the measurement properties of patient-reported outcome measures in radiotherapy-induced xerostomia. Oral Dis. 2020 May 17;: Authors: Assas M, Wiriyakijja P, Fedele S, Porter S, Ní Ríordáin R Abstract OBJECTIVE: Radiotherapy-induced xerostomia (RIX) is one of the most common adverse effects of radiotherapy to the head and neck, and a major determinant of survivors' quality of life. A number of patient-reported outcome measures...
Mon May 18, 2020 14:34
Related ArticlesA hybrid approach to tracheostomy in COVID-19 patients ensuring staff safety. Br J Surg. 2020 May 17;: Authors: Tanaka L, Alexandru M, Jbyeh S, Desbrosses C, Bouzit Z, Cheisson G, Papon JF, Nevoux J PMID: 32418207 [PubMed - as supplied by publisher]
Mon May 18, 2020 14:34
Related ArticlesDiffusion-weighted MRI: impact of the size of the ROI in detecting metastases in subcentimeter lymph nodes in head and neck squamous cell carcinoma. Neuroradiology. 2020 May 16;: Authors: Jović A, Fila J, Gršić K, Ivkić M, Ozretić D Abstract PURPOSE: Our aim is to determine the impact of the size of ROI in detecting subcentimeter metastatic lymph nodes in patients with head and neck squamous cell carcinoma (HNSCC). Secondary aim is...
Mon May 18, 2020 14:34
Related ArticlesThe effect of in-lab polysomnography and home sleep polygraphy on sleep position. Sleep Breath. 2020 May 16;: Authors: Kukwa W, Migacz E, Lis T, Ishman SL Abstract PURPOSE: Little is known regarding the influence of in-laboratory polysomnography (PSG) equipment on sleep position, especially on the prevalence of supine positioning, which in many cases may lead to a more severe sleep apnea diagnosis. The aim of this study was to assess...
Mon May 18, 2020 14:34
Related ArticlesThe embodiment of practice thresholds: from standardization to stabilization in surgical education. Adv Health Sci Educ Theory Pract. 2020 May 16;: Authors: Ott M, Apramian T, Lingard L, Roth K, Cristancho S Abstract Surgeons practice their own variations on a procedure. Residents experience shifting thresholds between variations that one surgeon holds firmly as principle and another takes more lightly as preference. Such variability...
Mon May 18, 2020 14:34
Related ArticlesIn vitro and in vivo Antiallergic Effects of Taurine on Allergic Rhinitis. Int Arch Allergy Immunol. 2020 May 15;:1-13 Authors: Zhou J, Lu Y, Li F, Wu W, Xie D, Feng Y Abstract BACKGROUND: The current treatment for allergic rhinitis (AR) is inadequate. OBJECTIVE: The present study aimed to investigate the therapeutic effect of taurine on AR and to identify the underlying molecular mechanisms. METHODS: The serum...
Mon May 18, 2020 14:34
Related ArticlesDosimetric measurement of scattered radiation for simulated head and neck radiotherapy with homemade oral phantom. J Xray Sci Technol. 2020 May 13;: Authors: Li KL, Lin JP, Chen YC, Lu CC Abstract During radiotherapy for head and neck tumours, the oral cavity and cheek area would be inevitably exposed to high energy radiation; thus, the material surface of the teeth, dental restorations with high atomic number, or alloy prosthodontics...
Mon May 18, 2020 14:34
Related ArticlesDevelopment and Implementation of an Educational Simulation Workshop in Fiberoptic Laryngoscopy for Radiation Oncology Residents. Int J Radiat Oncol Biol Phys. 2020 May 14;: Authors: Price JG, Spiegel DY, Yoo DS, Moravan MJ, Mowery YM, Niedzwiecki D, Brizel DM, Salama JK Abstract PURPOSE/OBJECTIVES: Fiberoptic laryngoscopy (FOL) is a critical tool for the diagnosis, staging, assessment of treatment response, and detection of recurrence...
Mon May 18, 2020 14:34
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