Related ArticlesDirect and indirect costs of adult patients with chronic rhinosinusitis with nasal polyps. Rhinology. 2020 May 16;: Authors: Lourijsen ES, Fokkens WJ, Reitsma S Abstract BACKGROUND: European direct and indirect cost data is missing for patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This study was aimed to establish the economic burden of CRSwNP based on a Dutch cohort of patients. METHODS: A cross-sectional...
Mon May 18, 2020 00:45
Related ArticlesQuantification of anticipation of excitement with a three-axial model of emotion with EEG. J Neural Eng. 2020 May 16;: Authors: Machizawa M, Lisi G, Kanayama N, Mizuochi R, Makita K, Sasaoka T, Yamawaki S Abstract OBJECTIVES: Multiple facets of human emotion underlie diverse and sparse neural mechanisms. Among the many existing models of emotion, the two-dimensional circumplex model of emotion is an important theory. The use of the circumplex...
Mon May 18, 2020 00:40
Self-adaptive shared control with brain state evaluation network for human-wheelchair cooperation. J Neural Eng. 2020 May 15;: Authors: Deng X, Yu ZL, Lin C, Gu Z, Li Y Abstract OBJECT: For the shared control systems, how to trade off the control weight between robot autonomy and human operator is an important issue, especially for BCI-based systems. However, most of existing shared controllers have paid less attention to the effects caused by subjects...
Sat May 16, 2020 16:43
Beta-band power modulation in the human hippocampus during a reaching task. J Neural Eng. 2020 May 15;: Authors: Martin Del Campo-Vera R, Gogia AS, Chen KH, Sebastian R, Kramer DR, Lee MB, Peng T, Tafreshi AR, Barbaro M, Liu C, Kellis S, Lee B Abstract Objective Characterize the role of the beta-band (13-30 Hz) in the human hippocampus during the execution of voluntary movement. Approach We recorded electrophysiological activity in human hippocampus...
Sat May 16, 2020 16:43
Electrochemical and biological characterization of thin-film platinum-iridium alloy electrode coatings: a chronic in vivo study. J Neural Eng. 2020 May 14;: Authors: Dalrymple AN, Huynh M, Nayagam BA, Lee C, Weiland GR, Petrossians A, Whalen Iii JJ, Fallon JB, Shepherd RK Abstract OBJECTIVE: To evaluate the electrochemical properties, biological response, and surface characterization of an electrodeposited Platinum-Iridium (Pt-Ir) electrode coating on...
Fri May 15, 2020 16:07
Changes of EEG phase synchronization and EOG signals along the use of steady state visually evoked potential-based brain computer interface. J Neural Eng. 2020 May 14;: Authors: Peng Y, Wang Z, Wong CM, Nan W, da Rosa AC, Xu P, Wan F, Hu Y Abstract The steady-state visual evoked potential (SSVEP)-based brain computer interface (BCI) has demonstrated relatively high performance with little user training, and thus becomes a popular BCI paradigm. However,...
Fri May 15, 2020 16:07
To assess the influence that several factors, such as the amount of obtained biopsies, difficult procedures, biopsy site and the experience of the attending physician, have on accuracy of flexible endoscopic biopsy (FEB).
Sun May 17, 2020 03:00
To report the outcome of unsedated office based Thulium laser therapy for Reinke's edema.
Sun May 17, 2020 03:00
The purpose of this study was to characterize the acoustic and aerodynamics of the voice of young men with prelingual deafness after cochlear implantation (CI) to provide a theoretical basis for their rehabilitation after CI.
Sat May 16, 2020 03:00
Paradoxical vocal fold motion (PVFM) is a disorder in which the vocal folds adduct inappropriately during inspiration resulting in episodic dyspnea and sometimes respiratory distress. Diagnosis is obtained through careful history, physical examination, flexible laryngoscopic examination with provocative maneuvers, and laryngeal electromyography. The pathogenesis and clinical findings of this disorder are not known.
Fri May 15, 2020 03:00
Related ArticlesLessons of the month: HLA-B27-associated syndrome and spontaneous intracranial hypotension resulting in behavioural variant frontotemporal dementia. Clin Med (Lond). 2020 May;20(3):e10-e11 Authors: Mandal AK, Ryatt A, O'Hare K, Missouris CG Abstract Spontaneous intracranial hypotension is uncommon and results from a cerebrospinal fluid (CSF) leak. We describe the case of a marathon runner who presented with postural headache attributable...
Mon May 18, 2020 00:34
Incidence of Unrecognized Incidental Durotomy during Surgery for Malignant Spinal Tumor. Spine Surg Relat Res. 2020;4(2):159-163 Authors: Koyama T, Sugita S, Hozumi T, Fujiwara M, Yamakawa K, Okuma T, Goto T Abstract Introduction: Cerebral spinal fluid leak from durotomy is a well-known risk with spinal surgeries. The aim of this study is to identify the incidence of unrecognized incidental durotomy during posterior surgery for spinal metastases and...
Fri May 15, 2020 15:54
Intrathecal blood injection: a case report of a rare complication of an epidural blood patch. BMC Neurol. 2020 May 13;20(1):187 Authors: Seemiller J, Challagundla S, Taylor T, Zand R Abstract BACKGROUND: Intrathecal injection is a rare complication of spinal anesthesia and an underreported complication of epidural blood patches. Although there are other reported cases of intrathecal blood injection, these cases lack confirmatory imaging and others report...
Fri May 15, 2020 15:54
Related ArticlesRecurrent Pneumococcal Meningitis in Children: A Multicenter Case-control Study. Pediatr Infect Dis J. 2019 09;38(9):881-886 Authors: Darmaun L, Levy C, Lagrée M, Béchet S, Varon E, Dessein R, Cohen R, Martinot A, Dubos F, ACTIV-GPIP Study Group Abstract BACKGROUND: Pneumococcal meningitis (PM) is a serious disease that can rarely recur at a later time after the initial episode. METHODS: A retrospective multicenter case-control...
Fri May 15, 2020 15:54
Related ArticlesCIPR: a web-based R/shiny app and R package to annotate cell clusters in single cell RNA sequencing experiments. BMC Bioinformatics. 2020 May 15;21(1):191 Authors: Ekiz HA, Conley CJ, Stephens WZ, O'Connell RM Abstract BACKGROUND: Single cell RNA sequencing (scRNAseq) has provided invaluable insights into cellular heterogeneity and functional states in health and disease. During the analysis of scRNAseq data, annotating the biological...
Mon May 18, 2020 00:20
Related ArticlesCSN: unsupervised approach for inferring biological networks based on the genome alone. BMC Bioinformatics. 2020 May 15;21(1):190 Authors: Galili M, Tuller T Abstract BACKGROUND: Most organisms cannot be cultivated, as they live in unique ecological conditions that cannot be mimicked in the lab. Understanding the functionality of those organisms' genes and their interactions by performing large-scale measurements of transcription levels,...
Mon May 18, 2020 00:20
Broad-coverage biomedical relation extraction with SemRep. BMC Bioinformatics. 2020 May 14;21(1):188 Authors: Kilicoglu H, Rosemblat G, Fiszman M, Shin D Abstract BACKGROUND: In the era of information overload, natural language processing (NLP) techniques are increasingly needed to support advanced biomedical information management and discovery applications. In this paper, we present an in-depth description of SemRep, an NLP system that extracts semantic...
Sat May 16, 2020 20:01
ICEKAT: an interactive online tool for calculating initial rates from continuous enzyme kinetic traces. BMC Bioinformatics. 2020 May 14;21(1):186 Authors: Olp MD, Kalous KS, Smith BC Abstract BACKGROUND: Continuous enzyme kinetic assays are often used in high-throughput applications, as they allow rapid acquisition of large amounts of kinetic data and increased confidence compared to discontinuous assays. However, data analysis is often rate-limiting...
Sat May 16, 2020 20:01
Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes. BMC Bioinformatics. 2020 May 14;21(1):187 Authors: Cao L, der Meer ADV, Verbeek FJ, Passier R Abstract BACKGROUND: Cardiotoxicity, characterized by severe cardiac dysfunction, is a major problem in patients treated with different classes of anticancer drugs. Development of predictable human-based models and assays for drug screening are...
Sat May 16, 2020 20:01
Related ArticlesLaryngeal suspension, combined with rehabilitation and nutritional support, improved the clinical course of a patient with sarcopenic dysphasia. Int J Surg Case Rep. 2020 May 11;70:140-144 Authors: Kasahara K, Okubo K, Morikawa J Abstract INTRODUCTION: Sarcopenic dysphasia is a relatively new disease concept describing impairments in swallowing resulting from a generalized loss of skeletal muscle mass. PRESENTATION OF CASE: In...
Mon May 18, 2020 00:18
Pilot Study of Quantitative Methods for Differentiating Pharyngeal Swallowing Mechanics by Dysphagia Etiology. Dysphagia. 2020 May 14;: Authors: Tadavarthi Y, Hosseini P, Reyes SE, Focht Garand KL, Pisegna JM, Pearson WG Abstract Quantitative analysis of modified barium swallow (MBS) imaging is useful to determine the impact of various disease states on pharyngeal swallowing mechanics. In this retrospective proof of concept study, kinematic analysis...
Sat May 16, 2020 16:13
The Gugging Swallowing Screen in dysphagia screening for patients with stroke: A systematic review. Int J Nurs Stud. 2020 Apr 18;107:103588 Authors: Park KD, Kim TH, Lee SH Abstract BACKGROUND: Dysphagia in patients with stroke can cause serious complications, such as aspiration and pneumonia, that often lead to increase in mortality and length of hospitalization. Several screening tests for dysphagia have been developed and are used in clinical practice...
Fri May 15, 2020 15:58
Related ArticlesWhat Is the Link Between Attention-Deficit/Hyperactivity Disorder and Sleep Disturbance? A Multimodal Examination of Longitudinal Relationships and Brain Structure Using Large-Scale Population-Based Cohorts. Biol Psychiatry. 2020 Mar 31;: Authors: Shen C, Luo Q, Chamberlain SR, Morgan S, Romero-Garcia R, Du J, Zhao X, Touchette É, Montplaisir J, Vitaro F, Boivin M, Tremblay RE, Zhao XM, Robaey P, Feng J, Sahakian BJ Abstract BACKGROUND:...
Mon May 18, 2020 00:12
Related ArticlesSustained effects of faculty leadership development modules for clinical instructors of core competences education in Taiwan: a four-year explanatory case study. BMC Med Educ. 2020 May 15;20(1):155 Authors: Lee FY, Yang YY, Huang CC, Huang LJ, Chang CC, Liang JF, Huang SS, Lee WS, Lu DY, Chuang CL, Yang LY, Huang HC, Shulruf B, Chen CH, Kao SY Abstract BACKGROUND: The Accreditation Council for Graduate Medical Education (ACGME) core competencies...
Mon May 18, 2020 00:04
A framework for distributed health professions training: using participatory action research to build consensus. BMC Med Educ. 2020 May 14;20(1):154 Authors: Van Schalkwyk SC, Couper ID, Blitz J, De Villiers MR Abstract BACKGROUND: There is a global trend towards providing training for health professions students outside of tertiary academic complexes. In many countries, this shift places pressure on available sites and the resources at their disposal,...
Sat May 16, 2020 15:44
Predictive validity of the National Benchmark Test and National Senior Certificate for the academic success of first-year medical students at one South African university. BMC Med Educ. 2020 May 13;20(1):152 Authors: Mabizela SE, George AZ Abstract BACKGROUND: South African medical schools use the results of the National Senior Certificate (NSC) examination for selecting students. Five of the nine medical schools also use the National Benchmark Test...
Fri May 15, 2020 15:11
Comparing empathy in medical students of two Portuguese medicine schools. BMC Med Educ. 2020 May 13;20(1):153 Authors: Santiago LM, Rosendo I, Coutinho ML, Maurício KS, Neto I, Simões JA Abstract BACKGROUND: Empathy is paramount in the doctor-patient relationship being a comprehensive and multidimensional concept. Self-ratings of empathy change across the years of medical education only when the Jefferson Scale of Physicians Empathy is used, with a worrying...
Fri May 15, 2020 15:11
Related ArticlesTBRG4 silencing promotes progression of squamous cell carcinoma via regulation of CAV-1 expression and ROS formation. Cell Mol Biol (Noisy-le-grand). 2020 May 16;66(2):157-164 Authors: Wang J, Luo Q, Liu M, Zhang C, Jia Y, Tong R, Yang L, Fu X Abstract Esophageal cancer is the eighth most common cancer globally. Transforming growth factor β regulator 4 (TBRG4) and caveolin-1 (CAV-1) are implicated in tumor progression. The aim of...
Sun May 17, 2020 23:55
Related ArticlesPreclinical and Dose-Finding Phase 1 Trial Results of Combined Treatment with a TORC1/2 Inhibitor (TAK-228) and Aurora A Kinase Inhibitor (Alisertib) in Solid Tumors. Clin Cancer Res. 2020 May 15;: Authors: Davis SL, Ionkina AA, Bagby SM, Orth JD, Gittleman B, Marcus JM, Lam ET, Corr BR, O'Bryant CL, Glode AE, Tan AC, Kim J, Tentler JJ, Capasso A, Lopez KL, Gustafson DL, Messersmith WA, Leong S, Eckhardt SG, Pitts TM, Diamond JR Abstract ...
Sun May 17, 2020 23:55
Related ArticlesMicrotubule-targeting agents and their impact on cancer treatment. Eur J Cell Biol. 2020 May 01;:151075 Authors: Čermák V, Dostál V, Jelínek M, Libusová L, Kovář J, Rösel D, Brábek J Abstract Microtubule-targeting agents (MTAs) constitute a diverse group of chemical compounds that bind to microtubules and affect their properties and function. Disruption of microtubules induces various cellular responses often leading to cell cycle...
Sun May 17, 2020 23:55
Related ArticlesCytotoxic Scalarane Sesterterpenes from the Sponge Hyrtios erectus. Mar Drugs. 2020 May 13;18(5): Authors: Kwon OS, Kim D, Kim CK, Sun J, Sim CJ, Oh DC, Lee SK, Oh KB, Shin J Abstract Twelve new sesterterpenes along with eight known sesterterpenes were isolated from the marine sponge Hyrtios erectus collected off the coast of Chuuk Island, the Federated State of Micronesia. Based upon a combination of spectroscopic and computational...
Sun May 17, 2020 23:55
New Insights of Human Parvovirus B19 in Modulating Erythroid Progenitor Cell Differentiation. Viral Immunol. 2020 May 15;: Authors: Feng S, Zeng D, Zheng J, Zhao D Abstract Human parvovirus B19 (B19), a human pathogen of the erythroparvovirus genus, is responsible for a variety of diseases. B19 cause less symptoms in healthy individuals, also cause acute and chronic anemia in immunodeficiency patients. Transient aplastic crisis and pure red cell...
Sat May 16, 2020 13:21
Co-ordinated regulation of cell survival and cell cycle pathways by DDR2-dependent SRF transcription factor in cardiac fibroblasts. Am J Physiol Heart Circ Physiol. 2020 May 15;: Authors: Titus AS, V H, Kailasam S Abstract Relative resistance to apoptosis and the ability to proliferate and produce a collagen-rich scar determine the critical role of cardiac fibroblasts in wound healing and tissue remodeling following myocardial injury. Identification...
Sat May 16, 2020 13:21
Antitumor effect of a pyrazolone-based-complex [Cu(PMPP-SAL)(EtOH)] against murine melanoma B16 cell in vitro and in vivo. Acta Pharm. 2020 Dec 01;70(4):561-575 Authors: Abula A, Zhao J, Xu G, Li Y, Sun S Abstract Pyrazolone-based derivative metal complexes were reported to have cytotoxicity in some tumor cells. In this study, the antitumor effect of [Cu(PMPP-SAL)(EtOH)] (PMPP-SAL = N-(1-phenyl-3-methyl-4-propenylidene-5-pyrazolone)- salicylidene...
Sat May 16, 2020 13:21
Unraveling Adipocytes and Cancer Links: Is There a Role for Senescence? Front Cell Dev Biol. 2020;8:282 Authors: Wu Q, Li B, Sun S, Sun S Abstract Senescence is characterized by a permanent cell cycle arrest that is elicited in response to different stresses. In addition, senescent cells undergo multiple other phenotypic alterations, such as autophagy modulation, metabolic reprogramming, and the senescence-associated secretory phenotype (SASP). These...
Sat May 16, 2020 13:21
PKMYT1 as a Potential Target to Improve the Radiosensitivity of Lung Adenocarcinoma. Front Genet. 2020;11:376 Authors: Long HP, Liu JQ, Yu YY, Qiao Q, Li G Abstract Objective: This article is dedicated to finding important genes related to the prognosis of lung adenocarcinoma (LUAD), looking for a new gene that may affect tumor radiosensitivity, and conducting basic experiments to verify the relationship between this gene and the radiosensitivity...
Sat May 16, 2020 13:21
Multiple Facets of Autophagy and the Emerging Role of Alkylphosphocholines as Autophagy Modulators. Front Pharmacol. 2020;11:547 Authors: Kaleağasıoğlu F, Ali DM, Berger MR Abstract Autophagy is a highly conserved multistep process and functions as passage for degrading and recycling protein aggregates and defective organelles in eukaryotic cells. Based on the nature of these materials, their size and degradation rate, four types of autophagy have...
Sat May 16, 2020 13:21
Long non-coding RNA OIP5-AS1 suppresses multiple myeloma progression by sponging miR-27a-3p to activate TSC1 expression. Cancer Cell Int. 2020;20:155 Authors: Wang Y, Wang H, Ruan J, Zheng W, Yang Z, Pan W Abstract Background: Multiple myeloma (MM) is a prevalent hematological malignancy. Long noncoding RNAs are correlated with the development of MM. In this project, the function of lncRNA opa interacting protein 5-antisense 1 (OIP5-AS1) in MM and...
Sat May 16, 2020 13:21
The anti-cancer effects of fucoidan: a review of both in vivo and in vitro investigations. Cancer Cell Int. 2020;20:154 Authors: Lin Y, Qi X, Liu H, Xue K, Xu S, Tian Z Abstract Fucoidan is a kind of the polysaccharide, which comes from brown algae and comprises of sulfated fucose residues. It has shown a large range of biological activities in basic researches, including many elements like anti-inflammatory, anti-cancer, anti-viral, anti-oxidation,...
Sat May 16, 2020 13:21
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