Nanoparticle immunological screen improves therapy [Engineering]

Immunological complexity in atherosclerosis warrants targeted treatment of specific inflammatory cells that aggravate the disease. With the initiation of large phase III trials investigating immunomodulatory drugs for atherosclerosis, cardiovascular disease treatment enters a new era. We here propose a radically different approach: implementing and evaluating in vivo a combinatorial library...

http://ift.tt/2fadGpl

Water permeation through transporters [Physiology]

Membrane transporters, in addition to their major role as specific carriers for ions and small molecules, can also behave as water channels. However, neither the location of the water pathway in the protein nor their functional importance is known. Here, we map the pathway for water and urea through the...

http://ift.tt/2fslQNv

General view of surface melting on ice crystals [Physics]

Since the pioneering prediction of surface melting by Michael Faraday, it has been widely accepted that thin water layers, called quasi-liquid layers (QLLs), homogeneously and completely wet ice surfaces. Contrary to this conventional wisdom, here we both theoretically and experimentally demonstrate that QLLs have more than two wetting states and...

http://ift.tt/2fsidqU

Crystal structure of the cohesin loader Scc2 [Biochemistry]

The ring-shaped cohesin complex topologically entraps chromosomes and regulates chromosome segregation, transcription, and DNA repair. The cohesin core consists of the structural maintenance of chromosomes 1 and 3 (Smc1–Smc3) heterodimeric ATPase, the kleisin subunit sister chromatid cohesion 1 (Scc1) that links the two ATPase heads, and the Scc1-bound adaptor protein...

http://ift.tt/2fslYMX

Design of a nanopore-polymerase for DNA sequencing [Applied Biological Sciences]

Scalable, high-throughput DNA sequencing is a prerequisite for precision medicine and biomedical research. Recently, we presented a nanopore-based sequencing-by-synthesis (Nanopore-SBS) approach, which used a set of nucleotides with polymer tags that allow discrimination of the nucleotides in a biological nanopore. Here, we designed and covalently coupled a DNA polymerase to...

http://ift.tt/2fa8Wjs

Human cortical-hippocampal dialogue [Neuroscience]

Declarative memory consolidation is hypothesized to require a two-stage, reciprocal cortical–hippocampal dialogue. According to this model, higher frequency signals convey information from the cortex to hippocampus during wakefulness, but in the reverse direction during slow-wave sleep (SWS). Conversely, lower-frequency activity propagates from the information "receiver" to the "sender" to coordinate...

http://ift.tt/2fskTF7

Two mechanisms in inositol pyrophosphate signaling [Biochemistry]

Inositol-based signaling molecules are central eukaryotic messengers and include the highly phosphorylated, diffusible inositol polyphosphates (InsPs) and inositol pyrophosphates (PP-InsPs). Despite the essential cellular regulatory functions of InsPs and PP-InsPs (including telomere maintenance, phosphate sensing, cell migration, and insulin secretion), the majority of their protein targets remain unknown. Here, the...

http://ift.tt/2fsoDGD

BIG SEEDS1 regulates lateral organ size [Agricultural Sciences]

Plant organs, such as seeds, are primary sources of food for both humans and animals. Seed size is one of the major agronomic traits that have been selected in crop plants during their domestication. Legume seeds are a major source of dietary proteins and oils. Here, we report a conserved...

http://ift.tt/2fskUJb

Structure of KRAS4b-PDE{delta} complex [Biochemistry]

Farnesylation and carboxymethylation of KRAS4b (Kirsten rat sarcoma isoform 4b) are essential for its interaction with the plasma membrane where KRAS-mediated signaling events occur. Phosphodiesterase-δ (PDEδ) binds to KRAS4b and plays an important role in targeting it to cellular membranes. We solved structures of human farnesylated–methylated KRAS4b in complex with...

http://ift.tt/2fadt5I

Randomized controlled trial of juzen-taiho-to in children with recurrent acute otitis media

Publication date: Available online 31 October 2016
Source:Auris Nasus Larynx
Author(s): Makoto Ito, Yumiko Maruyama, Ken Kitamura, Toshimitsu Kobayashi, Haruo Takahashi, Noboru Yamanaka, Yasuaki Harabuchi, Hideki Origasa, Tomokazu Yoshizaki
ObjectiveRecurrent acute otitis media (AOM) in young children is rapidly increasing worldwide. Repeated antibiotic use leads to antibiotic-resistant pathogen development. Complementary and alternative medicine approaches have been suggested as a supplemental treatment option to conventional antimicrobial medicine. This randomized, parallel-group, open-label, non-herbal medicine controlled trial assessed the efficacy of a traditional Japanese herbal medicine, juzen-taiho-to (JTT) for AOM prevention in otitis-prone children.MethodsChildren prone to recurrent AOM aged 6–48 months were recruited from 26 otolaryngology clinics in Japan and received conventional AOM treatment based on Japanese guidelines with or without 2 daily oral doses of JTT (0.10–0.25g/kg/day). The mean number of AOM episodes, coryza episodes, and duration of total antibiotic administration per month were compared during 3-month intervention.ResultsAt least one episode of AOM was diagnosed in 71% of JTT-group and 92% of control participants during follow-up. JTT administration reduced the frequency of AOM episodes by 57% compared with children who received conventional treatment alone (0.61±0.54 vs. 1.07±0.72 AOM instances/month; P=0.005) and also significantly decreased number of coryza episodes (P=0.015) and total antibiotic administration (P=0.024).ConclusionsThis is the first report of recurrent AOM prevention by herbal medication. JTT appears to effectively prevent recurrent AOM in children. Subsequent double-blind studies are needed to confirm the beneficial effects of JTT on recurrent AOM and upper respiratory tract infections.



http://ift.tt/2fBIcvx

MAP Tag: A Novel Tagging System for Protein Purification and Detection

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy , Vol. 0, No. 0.


http://ift.tt/2ewQHUu

William Eugene Mayberry (August 22, 1929–September 19, 2016)

Thyroid , Vol. 0, No. 0.


http://ift.tt/2eaDTSI

A comparison of single-handed chin lift and two-handed jaw thrust for tracheal intubation using a lightwand

Abstract

Purpose

In the present study, we evaluated the effects of single-handed chin lift and two-handed jaw thrust on lightwand-guided intubation and postoperative sore throat.

Methods

Sixty adult patients were included in the study. After induction of anesthesia, intubation was performed using a lightwand under single-handed chin lift or two-handed jaw thrust. In the single-handed chin lift group, the lightwand was inserted with the right hand after the mandible was lifted by placing the thumb of the left hand into the mouth. In the two-handed jaw thrust group, the lightwand was inserted while jaw thrust was achieved by an assistant using two hands. Lightwand search time, number of intubation attempts, and time to achieve intubation were assessed. Heart rate and mean arterial pressure were measured before and after intubation. Postoperative sore throat was evaluated at 1 and 24 h after surgery.

Results

Lightwand search time was significantly shorter in the two-handed jaw thrust group compared to the single-handed chin lift group (7.2 ± 4.6 vs. 12.1 ± 9.1 s, respectively; p = 0.016). The two-handed jaw thrust group had shorter intubation time than the single-handed chin lift group (21.0 ± 6.6 vs. 27.9 ± 9.9 s, respectively; p = 0.004). The number of intubation attempts and hemodynamic changes during intubation were similar between the two groups. The incidence and severity of postoperative sore throat were lower at 24 h after surgery in the two-handed jaw thrust group compared with the single-handed chin lift group (p = 0.011).

Conclusions

The two-handed jaw thrust facilitated lightwand-guided intubation, and reduced the incidence and severity of postoperative sore throat compared to the single-handed chin lift.

http://ift.tt/2eanttx

Magnesium in obstetric anesthesia and intensive care

Abstract

Magnesium, one of the essential elements in the human body, has numerous favorable effects that offer a variety of possibilities for its use in obstetric anesthesia and intensive care. Administered as a single intravenous bolus dose or a bolus followed by continuous infusion during surgery, magnesium attenuates stress response to endotracheal intubation, and reduces intraoperative anesthetic and postoperative analgesic requirements, while at the same time preserving favorable hemodynamics. Applied as part of an intrathecal or epidural anesthetic mixture, magnesium prolongs the duration of anesthesia and diminishes total postoperative analgesic consumption with no adverse maternal or neonatal effects. In obstetric intensive care, magnesium represents a first-choice medication in the treatment and prevention of eclamptic seizures. If used in recommended doses with close monitoring, magnesium is a safe and effective medication.

http://ift.tt/2fBhSkZ

Outcomes of physician patients after non-cardiac surgery: a registry analysis

Abstract

Objectives

When physicians become patients, they may expect special privileges, extra attention from caregivers, and non-routine treatments. Consequently, physician patients may not be treated per routine—which possibly worsens care rather than improving it. We thus tested the primary hypothesis that in-hospital mortality and major complications after non-cardiac surgery are more common in physician patients than in non-physician patients.

Patients and methods

Perioperative data were extracted for patients who had non-cardiac surgery at the Cleveland Clinic between 2005 and 2013. We used propensity score matching to identify comparable groups of physician and non-physician patients. Matched physician and non-physician patients were compared on a composite of in-hospital mortality and major postoperative complications using a generalized equation average relative effects model. Secondly, the matched patients were also compared on reoperation using logistic regression and on duration of hospitalization using Kaplan–Meier analysis with the log-rank test and Cox proportional hazards regression.

Results

Among 21,173 qualifying patients, we matched 522 physician patients to 2448 non-physician controls. There were no significant differences between physician and non-physician patients in the composite of in-hospital mortality and major complications, with an estimated odds ratio across the outcome components (average relative effect) of 1.20 (95% confidence interval 0.77–1.87) for physicians vs. non-physicians, P = 0.41. There was also no difference in the risk of re-operation or duration of hospitalization.

Conclusions

A variety of important outcomes were similar in physician patients and matched non-physician patients after non-cardiac surgery.

http://ift.tt/2ealHZn

Table of Contents

Publication date: November–December 2016
Source:American Journal of Otolaryngology, Volume 37, Issue 6





http://ift.tt/2fak9kz

Guidelines for Contributing Authors

Publication date: November–December 2016
Source:American Journal of Otolaryngology, Volume 37, Issue 6





http://ift.tt/2eRlUo2

Editorial Board

Publication date: November–December 2016
Source:American Journal of Otolaryngology, Volume 37, Issue 6





http://ift.tt/2falibW

Capacitance of Membrane As a Prognostic Indicator of Survival in Head and Neck Cancer

by Teresa Małecka-Massalska, Radosław Mlak, Agata Smoleń, Anna Brzozowska, Wojciech Surtel, Kamal Morshed

Background

Evaluation of prognostic value of capacitance of membrane (Cm), parameter measured by bioelectrical impedance (BIA) as an alternative to known clinical factors in patients with Head and Neck Cancer (HNC).

Methods

A cohort of 75 stage IIIB and IV HNC patients treated in Department of Otolaryngology, Head and Neck Surgery, Medical University of Lublin, Poland were prospectively evaluated. Cm measurements were performed in all patients using a bioelectrical impedance analyzer that was set on a frequency of 50 kHz. Results of Cm measurements were presented in nF. Survival differences were estimated using Kaplan–Meier method.

Results

Significantly higher Cm median was noted in well-nourished(n = 45) compared to malnourished (n = 30) patients (1.41 vs 1.01 respectively; p = 0.0009). Established in ROC curves analysis cut-off value (0.743) was characterized by 98% specificity and 37% sensitivity in the detection of malnutrition. Median overall survival (mOS) in the cohort was 32months. At the time of analysis deaths were recorded in 47 cases (62.7%). In patients who had Cm below the level of 0.743 risk of OS shortening was significantly higher than in other patients (12.1 and 43.4 months respectively; HR = 8.47, 95%CI: 2.91–24.66; χ² = 15.38, p = 0.0001).

Conclusion

Cm is a strong, independent prognostic factor in head and neck cancer.

http://ift.tt/2fBkH5D

Neuroimmune interactions: dendritic cell modulation by the sympathetic nervous system

Abstract

Dendritic cells are of paramount importance bridging innate and adaptive immune responses. Depending on the context, after sensing environmental antigens, commensal microorganisms, pathogenic agents, or antigens from the diet, dendritic cells may drive either different effector adaptive immune responses or tolerance, avoiding tissue damage. Although the plasticity of the immune response and the capacity to regulate itself are considered essential to orchestrate appropriate physiological responses, it is known that the nervous system plays a relevant role controlling immune cell function. Dendritic cells present in the skin, the intestine, and lymphoid organs, besides expressing adrenergic receptors, can be reached by neurotransmitters released by sympathetic fibers innervating these tissues. These review focus on how neurotransmitters from the sympathetic nervous system can modulate dendritic cell function and how this may impact the immune response and immune-mediated disorders.

http://ift.tt/2eR9e0L

Editorial Board

Publication date: November 2016
Source:Clinical Immunology, Volume 172





http://ift.tt/2eQSFlw

Preface

Publication date: November 2016
Source:Clinical Immunology, Volume 172
Author(s): Shu Man Fu, Robert Winchester




http://ift.tt/2f9NThx

Endovascular recanalization of the common carotid artery in a patient with radio induced chronic occlusion

Recanalization of chronic occlusion of the common carotid artery (CCA) in patients with a history of neck irradiation is challenging, both for vascular surgeons and interventional neuroradiologists. We describe a case of successful stenting of radio induced chronic occlusion of the right CCA in a 41-year-old patient with neurological deterioration and minor stroke due to cerebral hypoperfusion caused by concomitant bilateral arterial occlusions. Direct surgery and surgical bypass were considered contraindicated. The endovascular approach was successful and required multiple precautions during the procedure. We describe particular solutions, not used in day to day practice, that allowed us to carry out the endovascular treatment in this unusual situation.

http://ift.tt/2fdIwMG

Severe soft tissue infection masquerading as necrotising fasciitis in a 31-year-old woman with a background of right thigh arteriovenous malformation

A 31-year-old woman with a history of a right thigh arteriovenous malformation presented with an acute history of right thigh pain and swelling. This rapidly progressed to gross sepsis. She was intubated, requiring inotropic support and renal replacement therapy. She was considered disproportionately unwell, with the impression one of necrotising fasciitis (NF). She was taken to theatre for emergency exploration and debridement. There was no evidence of NF to note in theatre. Tissue samples cultured group C Streptococcus, with histopathological examination confirming group C Streptococcal soft tissue infection. Thereafter, she was treated with high-dose intravenous antibiotics, use of a negative pressure wound therapy system, and multiple returns to theatre for repeat debridement. Her condition gradually improved, and she was stepped down to a surgical ward 3 weeks after admission. Nine weeks after initial presentation, she underwent skin grafting for wound closure. She returned to work 7 months later.

http://ift.tt/2ejxAzB

Renal neuroendocrine tumour and synchronous pancreas metastasis: histopathological diagnosis using prostatic acid phosphatase

A woman aged 56 years developed 2 synchronous tumours: one, 1.2 cm in diameter at the head of the pancreas; and the other, 4.0 cm in diameter, at the left side of her horseshoe kidney. Preoperative differential diagnosis of these hypovascular lesions included pancreatic ductal carcinoma (PDC) with renal metastasis, PDC with renal angiomyolipoma, renal cell carcinoma with pancreatic metastasis or PDC and renal cell carcinoma. Following pancreaticoduodenectomy and left nephrectomy, both specimens were diagnosed as grade 2 neuroendocrine tumours (NETs). Immunohistochemistry revealed that both were positive for prostatic acid phosphatase (PAP), which is specific to hindgut-derived NET, including renal NET. Accordingly, the renal tumour was diagnosed as the primary lesion, and the pancreatic tumour as a metastasis. To the best of our knowledge, this is the first report of a renal NET with a synchronous pancreas metastasis. Immunohistochemical staining for PAP was a useful diagnostic marker for synchronous NETs in the kidney and pancreas.

http://ift.tt/2fdInsA

Oesophageal foreign body: the importance of imaging in multiple coin ingestion

Description

A woman aged 61 years presented to a district general hospital with a 5-day history of dysphagia, regurgitation of all liquids and solids and lower sternal pain. She had a background of metastatic lung cancer with brain metastases and had previously received chemotherapy and radiotherapy. She was intermittently confused and had no recollection of ingesting a foreign body. On examination, her oral cavity, oropharynx and neck were unremarkable. Plain chest X-ray revealed a midline opaque foreign body at the level of the clavicular heads in the shape of a single coin (figure 1). A lateral soft tissue neck X-ray revealed, on close inspection, the presence of two foreign bodies and these appeared to be two coins lying on top of one another at the approximate level of T3 (figure 2). The patient was fasted and taken to theatre for a rigid oesophagoscopy. Intraoperatively, two...

http://ift.tt/2ejo1jX

Leydig cell tumour and mature ovarian teratoma: rare androgen-secreting ovarian tumours in postmenopausal women

Androgen-secreting ovarian tumours are extremely rare accounting for <5% of all ovarian neoplasms. They are more frequent in postmenopausal women and should be suspected in the case of a rapid onset of androgenic symptoms. We report 4 cases of postmenopausal women who presented with signs of virilisation. All patients revealed increased serum levels of testosterone, normal dehydroepiandrosterone-sulfate and negative pelvic ultrasound for adnexal masses. An androgen-secreting ovarian tumour was suspected and all of them were submitted to bilateral oophorectomy. Histology confirmed the diagnosis of Leydig cell tumours in 3 patients and mature teratoma in 1. A successful response to surgery, which includes a decline in serum androgen levels and signs of hyperandrogenism, was observed in our patients. This case series demonstrates that androgen-secreting ovarian neoplasms may not be detectable by imaging studies, but should be considered in the differential diagnosis of all postmenopausal women with signs of hyperandrogenism.

http://ift.tt/2fdIrbH

Disconnected pancreatic duct syndrome: a multidisciplinary management dilemma

Disconnected pancreatic duct syndrome is a circumferential interruption of the pancreatic duct. It usually occurs secondary to pancreatitis and carries significant diagnostic and management challenges. We present a case of disconnected pancreatic duct syndrome that represented a diagnostic and management dilemma for both medical and surgical teams. The aim of this article is to share a successful management experience of disconnected pancreatic duct syndrome with other physicians and to perform a brief but focused literature review on this challenging condition.

http://ift.tt/2ejnWg9

Infected pseudoaneurysm of the left anterior descending artery

Primary percutaneous transluminal coronary angioplasty (PTCA) with the insertion of a stent is a well-established procedure for management of coronary artery disease. Infected pseudoaneurysms following PTCA and stenting are very rare and have poor outcomes if not managed properly. We are presenting a case of a man aged 50 years with infected pseudoaneurysm of the left anterior descending artery following multiple percutaneous interventions for coronary artery disease. In this paper, we have described the presentation, diagnosis and management of this patient and have discussed the aetiology and management options of infected pseudoaneurysm affecting coronary arteries.

http://ift.tt/2fdHAaT

Bilateral fractures in a shoulder dystocia delivery

Description

A male neonate weighing 4170 g (99th centile) was born to a non-diabetic primigravid woman by difficult vaginal delivery at 37 weeks gestation due to right shoulder dystocia. The labour was induced and Neville Barnes forceps were employed for successful delivery. Apart from maternal obesity (body mass index of 36 kg/m²), no other risk factors for fetal macrosomia or shoulder dystocia were noted. After birth, absent right shoulder movement with asymmetrical Moro reflex was noted, raising the possibility of right clavicular fracture with possible brachial plexus injury (BPI). Although left arm mobility was reduced, neurology was normal. Both elbows and wrists were flexed with symmetrical grasp reflex. A chest radiograph was performed, confirming displaced fractures of his right clavicle and left humerus (figure 1). Examination findings at 48 hours were unchanged, and there were no signs of Horner's syndrome or respiratory distress indicating phrenic nerve injury. It was difficult...

http://ift.tt/2ejqpam

Advanced gastric cancer linitis plastica presented with disseminated intravascular coagulation

An old man was found unconscious; on admission found to have disseminated intravascular coagulation with concern of upper gastrointestinal bleed after he was found to have melena. Esophagogastroduodenoscopy on admission showed diffuse thickened gastric folds, and biopsy showed mucosal oedema. Bone marrow biopsy concerning for lymphoma was obtained showed adenocarcinoma. MRI of the abdomen was significant for diffuse gastric wall thickening. A repeat endoscopic ultrasound showed a diffuse gastric wall thickening of 15 mm and submucosal tunneling technique biopsy suggested high-grade, invasive, signet ring adenocarcinoma of the stomach. Oncology was consulted to initiate palliative chemotherapy. In retrospect, the patient was questioned regarding gastrointestinal symptoms; he reported gradual early satiety, dysphagia and unintentional weight loss over the course of 4 months.

http://ift.tt/2fdNusy

Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension

Jordan, J; Toplak, H; Grassi, G; Yumuk, V; Kotsis, V; Engeli, S; Cuspidi, C; Jordan, J; Toplak, H; Grassi, G; Yumuk, V; Kotsis, V; Engeli, S; Cuspidi, C; Nilsson, PM; Finer, N; Doehner, W; - view fewer (2016) Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension. Journal of Hypertension , 34 (9) pp. 1678-1688. 10.1097/HJH.0000000000001013 .

http://ift.tt/2e9XpP2

Cost-Efficient Low Latency Communication Infrastructure for Synchrophasor Applications in Smart Grids

Yang, B; Katsaros, KV; Chai, WK; Pavlou, G; (2016) Cost-Efficient Low Latency Communication Infrastructure for Synchrophasor Applications in Smart Grids. IEEE Systems Journal 10.1109/JSYST.2016.2556420 . (In press). Green open access

http://ift.tt/2fAPOhQ

Energy on the Move: Treaties on Transit of Energy via Pipelines

Azaria, D; (2017) Energy on the Move: Treaties on Transit of Energy via Pipelines. In: Proceedings of the 2016 Annual Meeting of American Society of International Law. American Society of International Law (ASIL): Washington, D.C., USA. (In press). Green open access

http://ift.tt/2ea0vCz

Countermeasures and Bespoke Pipeline Treaties

Azaria, D; (2017) Countermeasures and Bespoke Pipeline Treaties. Journal of International Dispute Settlement (In press).

http://ift.tt/2fAQaop

Pathological and phylogenetic characterization of Amphibiothecum sp. infection in an isolated amphibian (Lissotriton helveticus) population on the island of Rum (Scotland)

Fiegna, C; Clarke, CL; Shaw, DR; Baily, JL; Clare, FC; Gray, A; Garner, TWJ; Fiegna, C; Clarke, CL; Shaw, DR; Baily, JL; Clare, FC; Gray, A; Garner, TWJ; Meredith, AL; - view fewer (2016) Pathological and phylogenetic characterization of Amphibiothecum sp. infection in an isolated amphibian (Lissotriton helveticus) population on the island of Rum (Scotland). Parasitology (In press).

http://ift.tt/2ea1se9

Whaling and International Law

Azaria, D; (2017) Whaling and International Law. [Review]. British Yearbook of International Law (In press).

http://ift.tt/2fAREPz

Molecular and atomic gas along and across the main sequence of star-forming galaxies

Saintonge, A; Catinella, B; Cortese, L; Genzel, R; Giovanelli, R; Haynes, MP; Janowiecki, S; Saintonge, A; Catinella, B; Cortese, L; Genzel, R; Giovanelli, R; Haynes, MP; Janowiecki, S; Kramer, C; Lutz, KA; Schiminovich, D; Tacconi, LJ; Wuyts, S; Accurso, G; - view fewer (2016) Molecular and atomic gas along and across the main sequence of star-forming galaxies. Monthly Notices of the Royal Astronomical Society , 462 (2) pp. 1749-1756. 10.1093/mnras/stw1715 . Green open access

http://ift.tt/2e9Xr9y

Letter to Editor

Butcher, AL; Richards, T; (2016) Letter to Editor. European Journal of Obstetrics and Gynecology and Reproductive Biology 10.1016/j.ejogrb.2016.10.025 . (In press).

http://ift.tt/2fARhVe

Self-organising Networks in Complex Infrastructure Projects

Pryke, S; Badi, SM; Soundararaj, B; Addyman, S; (2016) Self-organising Networks in Complex Infrastructure Projects. Project Management Journal (In press). Green open access

http://ift.tt/2e9X4Ms

Differential sensitivity of radionuclide ventriculography for the detection of anterior and inferior infarction.

Underwood, SR; Walton, S; Laming, PJ; Ell, PJ; Emanuel, RW; Swanton, RH; (1988) Differential sensitivity of radionuclide ventriculography for the detection of anterior and inferior infarction. Br Heart J , 60 (5) pp. 411-416.

http://ift.tt/2fATAHK

Postoperative analgesia for Enhanced recovery in Joint replacement: Audit of a new electronic prescribing order set

Wright, J; Cullinger, B; Bacarese-Hamilton, I; (2015) Postoperative analgesia for Enhanced recovery in Joint replacement: Audit of a new electronic prescribing order set. BMJ Quality Improvement Reports , 4 (1) u209187.w3753. 10.1136/bmjquality.u209187.w3753 . Green open access

http://ift.tt/2e9X672

Spanish Civil War caves of Asturias in archaeology and memory

Fernández Fernández, J; Moshenska, G; (2016) Spanish Civil War caves of Asturias in archaeology and memory. International Journal of Heritage Studies 10.1080/13527258.2016.1232658 . (In press). Green open access

http://ift.tt/2fAQ9AR

Comparison of health examination survey methods in Brazil, Chile, Colombia, Mexico, England, Scotland and the USA

Mindell, JS; Moody, A; Vecio-Ortiz, A; Alfaro, A; Frenz, P; Scholes, S; Gonzalez, SA; Mindell, JS; Moody, A; Vecio-Ortiz, A; Alfaro, A; Frenz, P; Scholes, S; Gonzalez, SA; de Oliveira, C; Sanchez-Romero, LM; Alvarado, A; Cabrera, S; Sarmiento, OL; Triana, CA; Barquera, S; - view fewer (2016) Comparison of health examination survey methods in Brazil, Chile, Colombia, Mexico, England, Scotland and the USA. American Journal of Epidemiology (In press).

http://ift.tt/2ea0qPr

Care and Flow: Using Soft Systems Methodology to understand tensions in the patient discharge process

Emes, MR; Smith, S; Ward, S; Smith, A; Ming, T; (2017) Care and Flow: Using Soft Systems Methodology to understand tensions in the patient discharge process. Health Systems (In press).

http://ift.tt/2fARc3I

Liberal oxygenation in paediatric intensive care: retrospective analysis of high-resolution SpO2 data

Ray, S; Rogers, L; Raman, S; Peters, MJ; (2016) Liberal oxygenation in paediatric intensive care: retrospective analysis of high-resolution SpO2 data. Intensive Care Medicine 10.1155/2016/6312970 . (In press).

http://ift.tt/2e9Waj0

Concurrent Validity and Feasibility of Short Tests Currently Used to Measure Early Childhood Development in Large Scale Studies

Rubio-Codina, M; Araujo, MC; Attanasio, O; Munoz, P; Grantham-McGregor, S; (2016) Concurrent Validity and Feasibility of Short Tests Currently Used to Measure Early Childhood Development in Large Scale Studies. PLoS ONE , 11 (8) , Article e0160962. 10.1371/journal.pone.0160962 . Green open access

http://ift.tt/2fAP7oz

Towards a walkability model for strategic evaluation of policy action and urban active transport interventions

Dhanani, AN; Vaughan, L; (2016) Towards a walkability model for strategic evaluation of policy action and urban active transport interventions. In: (Proceedings) 48th Meeting of the Universities' Transport Study Group (UTSG), 6-7 January 2016, Bristol, UK. Universities' Transport Study Group (UTSG) (In press).

http://ift.tt/2e9Y56W

Adaptive structures for whole-life energy savings

Senatore, G; Duffour, P; Hanna, S; Labbé, F; Winslow, P; (2011) Adaptive structures for whole-life energy savings. Journal of the International Association for Shell and Spatial Structures , 52 (170) pp. 233-240. Green open access

http://ift.tt/2fAQRyf

Adaptive Building Structures - Two Case Studies

Senatore, GS; Duffour, PD; Winslow, PW; (2016) Adaptive Building Structures - Two Case Studies. In: (Proceedings) Proceedings of the International Association for Shell and Spatial Structures Annual Symposium 2016 - "Spatial Structures in the 21st Century". IASS (In press). Green open access

http://ift.tt/2e9XOBi