Parameters of skull vibration-induced nystagmus in normal subjects

Abstract

Hypothesis

The knowledge of vibration-induced nystagmus test (SVINT) values in the normal population is highly relevant to provide a rapid orientation on the diagnosis attitude in a patient with vertigo.

Background

Although mastoid bone vibration should only induce nystagmus in the presence of vestibular asymmetry, it has also been reported in normal individuals raising doubts as to how to interpret the SVINT. To date, no population studies involving the use of the SVINT and that establish normative values have been published.

Methods

This study was carried out at two tertiary healthcare centres on a total of 122 subjects. We stimulated at three frequencies (30, 60 and 100 Hz), in increasing order, first stimulating the right mastoid and then the left mastoid, and waiting for 30 s between each stimulus. The response was recorded with a videonystagmography system. The following variables were evaluated in each subject: the mean and maximum speed of the slow phase of nystagmus, the frequency of the nystagmatic response (NR) and the component and direction of the rapid phase of nystagmus.

Results

Only 26 subjects (20.5%) of the subjects studied here (122 subjects) developed any kind of nystagmatic response and 96 subjects (79.5%) did not display any response. Stimulation at 100 Hz provoked the largest number of responses (p = 0.04), while there was no difference in the number of responses induced by 30 and 60 Hz stimulations (p = 0.85). The frequency of nystagmus was ≤ 0.7 n/s in 80.8% of the positive responses. The mean velocity of the horizontal component of the NR was 2.2°/s (SD 1.6) and that of the vertical component was 1.3°/s (SD 1.2).

Conclusions

Healthy subjects do not generally develop to NR upon vibratory stimulation and only 20% of the subjects studied here developed any kind of NR, this being a slow and inconsistent response of low frequency. The establishment of normal values contributes to improve the orientation in clinical practice in the pathological population and this opens possibilities for tackling more reliable studies in this population.

https://ift.tt/2xvUOxT

Pediatric Residents’ Assessment of Atopic Dermatitis Severity for Risk Assessment of Early Peanut Introduction,

Publication date: Available online 31 May 2018
Source:Annals of Allergy, Asthma & Immunology
Author(s): James Shea, Monika Martusiewicz, Lucy A Bilaver, Ozge N Aktas, Jialing Jiang, Anthony J Mancini, Ruchi S Gupta




https://ift.tt/2L73HQg

Development of Food Protein-Induced Enterocolitis Syndrome (FPIES) to egg following Immunoglobulin E (IgE)-mediated egg allergy,

Publication date: Available online 31 May 2018
Source:Annals of Allergy, Asthma & Immunology
Author(s): Hannah Duffey, Maureen Egan




https://ift.tt/2JheLx1

Pilot study of the CAPS (Clinical extent, Area, Pruritus, Sleep) measure for atopic dermatitis severity,,✯✯✯,✯✯✯✯

Publication date: Available online 31 May 2018
Source:Annals of Allergy, Asthma & Immunology
Author(s): Aaron M Drucker, Natalie H Matthews, Jennie Muglia, Abrar A Qureshi
Eczema; Atopic dermatitis; Outcome measures; Severity; Symptoms; ItchAbbreviations: AD, atopic dermatitis; BSA, body surface area; CAPS, Clinical extent, Area, Pruritus, Sleep; DLQI, Dermatology Life Quality Index; EASI, Eczema Area and Severity Index; IGA, Investigator Global Assessment; POEM, Patient-Oriented Eczema Measure



https://ift.tt/2Ld5rrd

Otolaryngology resident experience with supraclavicular, submental and other regional flaps in the United States

Despite the resurgence in regional flap use, otolaryngology resident regional flap experience has been incompletely studied. We sought to characterize United States (US) otolaryngology resident exposure to, and perceptions of, supraclavicular flaps (SCFs), submental flaps (SMFs), and other regional flaps.

https://ift.tt/2socB53

“Determination of the impact of melanoma surgical timing on survival using the National Cancer Database”

https://ift.tt/2J1Mrj1

Association of family structure with atopic dermatitis in United States children

The relationship between family structure and atopic dermatitis has not previously been elucidated., Children from family structures without two married, biological parents have increased odds of AD and poorer overall health outcomes., Children from family structures without two, married, biological parents may benefit from increased surveillance, closer follow-up and optimized treatment for incident AD.

https://ift.tt/2H9ApOz

Daily Oxymetazoline Cream Demonstrates High and Sustained Efficacy in Patients With Persistent Erythema of Rosacea Through 52 Weeks of Treatment

https://ift.tt/2J47CBb

Long-term adalimumab efficacy in patients with moderate-to-severe hidradenitis suppurativa/acne inversa: 3-year results of a phase 3 open-label extension study

Adalimumab is approved for moderate-to-severe hidradenitis suppurativa/acne inversa., A sustained response is seen through week 168 in 52.3% of patients treated with adalimumab 40 mg weekly, with no additional safety issues identified. Adalimumab can be considered for long term control of moderate-to-severe hidradenitis suppurativa.

https://ift.tt/2syXOnE

The readability of iPledge program patient education materials

https://ift.tt/2J43aC4

A cohort study of risk factors, clinical presentations and outcomes for dermatophyte, non-dermatophyte and mixed toenail infections

https://ift.tt/2H9sK2Q

Response to: Reply to:"Determination of the impact of melanoma surgical timing on survival using the National Cancer Database"

https://ift.tt/2kGf8DE

Changes in chronic rhinosinusitis symptoms differentially associate with improvement in general health-related quality of life

Chronic rhinosinusitis (CRS) is an inflammatory disease of the paranasal sinus mucosa.1 CRS is characterized by nasal as well as extra-nasal symptoms related to poor sleep, ear/facial discomfort and emotional disturbance.2 Due to these associated symptoms as well as other clinical manifestations—such as acute exacerbations of CRS and exacerbation of comorbid pulmonary disease—CRS causes a significant quality of life (QOL) detriment.3–5 The clinical manifestations of CRS are also associated with significant productivity losses.

https://ift.tt/2JmLCAw

Food-induced Anaphylaxis in Infants and Children

Recent recommendations to introduce peanut products to infants for peanut allergy prevention requires a focused assessment of infant anaphylaxis.

https://ift.tt/2L8MUN2

Bedroom Exposure to Airborne Allergens in the Chicago Area Using a Patient-Operated Sampling Device

Background: In current practice, allergens in vacuum collected dust are used as surrogates for inhalable allergens. We developed an airsampling device that can be used by patients themselves for direct measurement of airborne allergen concentrations in their own homes.Objective: To demonstrate the use of this device to establish allergen concentration reference ranges in a target population. To evaluate relationships of patient-reported information to measured allergen concentrations.Methods: Patients from 5 allergist's practices in the Chicagoland region were provided with instructions, questionnaire, informed consent forms and samplers to run for 5 days in their bedrooms.

https://ift.tt/2JjVqLB

Are there different subtypes of eosinophilic esophagitis?

Currently, eosinophilic esophagitis (EoE) is defined by the combination of clinical symptoms and pathologic findings. Patients should have symptoms of esophageal dysmotility as well as a defined (albeit somewhat arbitrarily so) level of esophageal eosinophilia. Thus, using this definition, the diagnosis of EoE is purely a phenotype, possibly allowing for multiple different etiologies to funnel into this diagnosis. In this manner, EoE is similar to other conditions that we treat, such as asthma, in which treatment strategies are evolving in an era of precision medicine.

https://ift.tt/2Ldda8Z

Dehiscencia de la lámina papirácea del etmoides

Publication date: Available online 30 May 2018
Source:Acta Otorrinolaringológica Española
Author(s): Gabriel Huguet Llull, Marta Mesalles Ruiz, Xavier González Compta




https://ift.tt/2xvQ0Zt

Extranodal involvement of diffuse large B-cell lymphoma in the head and neck: An indicator of good prognosis

In this study, we analyzed clinicopathological characteristics and survival outcomes according to extranodal involvement of diffuse large B-cell lymphoma (DLBCL) in the head and neck.

https://ift.tt/2xwLh9Y

Pediatric cochlear reimplantation: Decision-tree efficacy

Publication date: Available online 31 May 2018
Source:European Annals of Otorhinolaryngology, Head and Neck Diseases
Author(s): L. Distinguin, M. Blanchard, I. Rouillon, M. Parodi, N. Loundon
ObjectivesThe context leading to pediatric cochlear reimplantation (CreI) can be complex. The objectives of this study were to define initial CreI indications, analyze final diagnosis and draw up a decision-tree.MethodsA retrospective study included patients undergoing CreI between 2005 and 2015. Demographic characteristics, CreI circumstances and technical reports were collected. Circumstances indicating CreI were classified in 3 groups: performance decrement, suspected device failure, or medical. After CreI, final diagnoses were classified in 2 groups: confirmed failure (DFail) or medical (DMed).Results69 out of 734 cochlear implantation surgeries were for CreI (8%). Manufacturers' reports were available in 64 cases (93%). Two principal causes were found: trauma and infection. Initial indications were: performance decrement: 27%; device failure: 56%; and medical: 17%. Final diagnoses were: DFail: 72%; and DMed: 28%. Initial indication and final diagnosis were similar in 86% of cases. The majority of the 14% initial indication errors belonged to the "performance decrement" group. Traumatic causes correlated with risk of initial indication error (P=0.039).ConclusionApart from spontaneous device failure, the two causes of CreI were infection and trauma. Using the present decision algorithm, half of the complex cases were resolved after CreI.



https://ift.tt/2J2ljQY

Tonsillectomy in children and in adults: changes in practice following the opening of a day-surgery unit with dedicated operating room

Publication date: Available online 30 May 2018
Source:European Annals of Otorhinolaryngology, Head and Neck Diseases
Author(s): S. Bartier, I. Gharzouli, N. Kiblut, H. Bendimered, L. Cloutier, D. Salvan
ObjectivesTo study the impact of the opening of a day-surgery unit on the practice of tonsillectomy in adults and children in the light of the experience of our department, and to compare complications between day-surgery and conventional admission.Material and methodsA retrospective review was conducted of all tonsillectomies performed since the opening of a dedicated day-surgery room, using the ENT and emergency department data-bases.ResultsBetween October 2013 and December 2014, 179 tonsillectomies were performed (51 in adults, 128 in children), including 108 day-surgeries. Between 2012 and 2014, the number of tonsillectomies increased by 12.7%, with an 18.27% increase in children and stable adult rate. Within 1 year, day-surgery became predominant for children (73.19%) and equaled conventional admission for adults (47.22%). For almost all patients without same-day discharge, the reasons were organizational or due to malorientation (comorbidity, or unsuitable home environment). Day-case tonsillectomy in children showed a 30-day complications rate comparable to those reported in the literature (8.3% postoperative hemorrhage), with a higher rate in adults (35.3%). Onset of complications was at a mean 6 days in adults and 9 days in children; only 2 patients developed complications between 6 and 24hours postoperatively.ConclusionThe present study showed that opening a day-surgery unit led to changes in practice, with most tonsillectomies now performed on an outpatient basis, without increased complications, and notably immediate complications. Outpatient tonsillectomy thus seems to be a solution of choice compared to conventional admission, in terms of cost saving and of patient comfort, without sacrificing safety. The dedicated operating room facilitates scheduling and thereby increasing turnover by reducing wait time.



https://ift.tt/2Haonob

Revisiting Correlation Between Pre Operative High Resolution Computed Tomography and Operative Findings in Attico Antral Disease

Abstract

(1) To correlate the findings of high resolution computed tomography (HRCT) scans with operative findings in chronic otitis media (attico antral disease). (2) To assess the role of HRCT in chronic otitis media (attico antral disease). This prospective observational study undertaken at a tertiary level teaching hospital included 50 patients of chronic otitis media (attico antral disease) who underwent pre-operative HRCT scanning and the findings were compared with the operative findings and correlation between the two was assessed with appropriate statistical methods. HRCT findings correlated well for the status of malleus and incus, facial nerve canal, lateral semicircular canal, and sinus plate but were less accurate for stapes and tegmen plate. As for disease extent and prediction of cholesteatoma the degree of correlation was site dependent being greater in mastoid air cell system and epitympanum and lesser in mesotympanum and hypotympanum. HRCT despite of its value in management of chronic otitis media has its drawbacks and limitations. CT's accuracy of prediction in some aspects of the disease varies with the site of pathology and this point must always be kept in mind by the operating surgeon. We suggest that each health care centre should establish their own correlative indices for HRCT temporal bone imaging in COM. HRCT cannot be entirely relied upon in management of chronic otitis media patients. However against the backdrop of improved radiological skills in interpreting temporal bone ct images, improved CT machines and importantly the growing concern over medicolegal issues, the role of pre operative CT scan in COM is much more than what was thought previously. Undoubtedly, it is a very useful 'aid' to management BUT a well-trained, experienced and alert surgeon is the key for an accurate diagnosis and successful management of chronic otitis media (attico-antral disease).

https://ift.tt/2snPXd3

Parotid Gland Tumours: Our Experience

Abstract

Salivary gland tumor comprises of approximately 3 to 10% of neoplasms of the head and neck region. Parotid gland is the most commonly involved salivary gland with an incidence of 62% followed by submandibular gland and other minor salivary gland tumors. However clinical course of benign and malignant tumors resemble each other in clinical findings, we require histopatholocal or cytological diagnosis for planning of management. To analyze parotid tumors retrospectively with following objectives. (1) Demographic distribution of parotid tumors. (2) To evaluate cytological and histopathological findings of parotid tumors. (3) Correlation of cytological and histopathological findings of parotid tumors. It was a retrospective observational study involving 31 patients who presented with parotid region swelling. Pre operative FNAC (fine needle aspiration cytology) and post operative histopathology were correlated. Surgical management depended on nature of disease. Correlation of FNAC and Histopathology: among 27 cases pre operative FNAC and post operative histopathology was same and in only 3 cases reports differed. One FNAC was inconclusive. In present study, Sensitivity of FNAC is 81.81%, Specificity is 94.73% and accuracy is 90%. FNAC is usually the first investigative modality, as it is a minimally invasive, cheap, OPD procedure that can differentiate benign from malignant tumors. Knowing preoperative pathological nature of disease can help in planning of surgical process.

https://ift.tt/2supiL7

Anaplastic carcinoma of the pancreas diagnosed by endoscopic ultrasound-guided fine-needle aspiration: a case report and review of the literature

Anaplastic carcinoma of the pancreas is a rare pancreatic neoplasm with a poor prognosis. It is classified as a variant of ductal adenocarcinoma, but the clinical features and treatment of it remain unknown be...

https://ift.tt/2suIbxd

Gallbladder metastasis of renal clear cell carcinoma 15 years after primary cancer excision: a case report

Renal cell carcinoma is well-known for its propensity to metastasize to unusual sites. However, metastasis to the gallbladder has been rarely reported in the literature.

https://ift.tt/2IZg1FM

Differential regulation of human monocytes and NK cells by antibody-opsonized tumors

Abstract

The monocyte network is important for therapeutic efficacy of antibody therapies against cancer. One mechanism which monocytes/macrophages use to kill cancer cells is phagocytosis. Using trastuzumab and human breast cancer cell lines as a model, we used flow cytometry to evaluate the importance of avidity, antigen density, Fcγ receptor (FcγR) expression, and FcγR polymorphisms in human monocyte phagocytosis. By increasing avidity for the tumor through the addition of pertuzumab to trastuzumab, there was a two-to-threefold increase in phagocytosis potency against the HCC1419 cell line compared to antibodies alone, while NK cell-mediated antibody-dependent cellular cytotoxicity (ADCC) failed to increase tumor cell death. Consistent with increasing the avidity through multiple antibodies, antigen density significantly enhanced phagocytosis with breast cancer cell lines that were HER2 gene-amplified compared to non-amplified tumor cells. Confirmation that high antigen density enhanced phagocytosis was obtained when HER2 was overexpressed in HER2 non-amplified cell lines. In contrast, NK cell ADCC failed to distinguish differences in tumor cell death when comparing gene-amplified and non-amplified breast cancer cell lines. The level of phagocytosis was influenced by FcγRIIa and FcγRIIIa expression. Most monocytes are FcγRIIIa⁻, and the induction of the receptor significantly enhances antibody-dependent phagocytosis. Although both receptors are involved, when blocked FcγRIIIa had a greater influence on phagocytosis. Furthermore, the polymorphism FcγRIIIa 158V significantly enhanced phagocytosis; whereas FcγRIIa 131H polymorphism appeared to improve phagocytosis but was not statistically significant. Targeting of monocytes for enhanced phagocytosis may improve the effectiveness of therapeutic antibodies to improve clinical outcomes.

https://ift.tt/2H7tu8S

Early Labor Symptoms

As pregnancy brings many normal changes for your body, it can be challenging to identify early labor symptoms that may point to premature labor, even if you are far from your due date. So how can you know if you are experiencing preterm labor? Here are the symptoms you may be able to recognize at home.

The post Early Labor Symptoms appeared first on ChildrensMD.

https://ift.tt/2sk6leQ

Adenopharyngoplasty vs Adenotonsillectomy in Children With Severe Obstructive Sleep Apnea

This randomized clinical trial compares the outcomes of adenotonsillectomy vs adenopharyngoplasty in children with severe obstructive sleep apnea.

https://ift.tt/2J2mCva

Association of Idiopathic Sudden Sensorineural Hearing Loss With Affective Disorders

This cohort study uses a Korean nationwide database to investigate whether idiopathic sudden sensorineural hearing loss is associated with the development of affective disorders such as anxiety, depression, and bipolar disorder.

https://ift.tt/2LMmVfe

The Unrecognized Dangers of Sudden Hearing Loss

The impact of an idiopathic sudden sensorineural hearing loss (ISSNHL) on a patient can be devastating. Practitioners who treat this malady are always worried about potential life-threatening issues, such as an intracranial complication or a tumor. However, practitioners need to be aware of other life-altering consequences of a sudden hearing loss. The study by Kim et al reveals that an often-overlooked sequela is the onset of affective disorders such as depression and anxiety.

https://ift.tt/2xr7KVI

Functional Nasal Surgery and Use of CPAP in OSAS Patients: Our Experience

Abstract

The surgical correction of nasal obstruction is definitely effective and recommended in patients with poor CPAP compliance, often secondary to the high pressures that need to be given in patients with nasal sub stenosis. For this reason, the objective of this study is the evaluation of the effectiveness and effects of the functional nose surgery on adherence to CPAP- therapy in patients (with moderate to severe OSAS with indication of ventilation therapy) poorly compliant with CPAP. The study was performed on a sample of 52 patients, 40 male and 12 female, aged between 29 and 72 years followed by the Otolaryngology Unit of the University Palermo in the period between January 2015 and January 2017. All patients were subjected to the following s iter: anamnesis with Epworth Sleepiness Scale, NOSE scale, evaluation of "CPAP usage data." Upper airway optical fiber endoscopy with Müller's maneuver. We performed various type of nasal surgery (septoplasty, decongestion of the lower turbinates and FESS) 6 months after the surgery, CPAP usage was evaluated and the NOSE scale has been reapplied. All patients had a subjective degree of obstruction classified in severe or extreme by the NOSE scale before surgery. Almost all patients reported a mild degree of obstruction after the surgery. About CPAP usage, the average usage has passed by 2, 3 h at night to 6, 8 h after the surgery. The result is significant because it shows how the nasal functional surgery can make selected patients suitable to ventilation therapy. As our work shows, a better nasal function allows to reduce the CPAP pressure, Therefore, we believe that all patients with medium to severe obstructive apnea syndrome and for whom night-time ventilation therapy (CPAP) is advised should be evaluated with endoscopy and anamnesis oriented to evaluate nasal obstructive pathologies that may reduce effectiveness of CPAP.

https://ift.tt/2J7C5KA

Nrf2 pathway modulates Substance P-induced human mast cell activation and degranulation in the hair follicle

Publication date: Available online 31 May 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Laura Jadkauskaite, Rajia Bahri, Nilofer Farjo, Bessam Farjo, Gail Jenkins, Ranjit Bhogal, Iain Haslam, Silvia Bulfone-Paus, Ralf Paus

Teaser

Activation of Nrf2 in primary human mast cells exposed to oxidative stress induced by substance P suppresses pro-inflammatory gene transcription, activation and degranulation.


https://ift.tt/2JoZ1bg

Paradoxical psoriasis following anti-TNF therapy in ankylosing spondylitis: A population-based cohort study

Publication date: Available online 31 May 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Jung Min Bae, Hyuck Sun Kwon, Gyong Moon Kim, Kyung-Su Park, Ki-Jo Kim

Teaser

The risks of psoriasis and palmoplantar pustulosis were significantly increased in patients with ankylosing spondylitis (AS) treated with anti-TNF agents compared to AS patients treated without anti-TNF agents in the population-based cohort study.


https://ift.tt/2LcPYI2

Biological Therapies for Eosinophilic Gastrointestinal Diseases

Publication date: Available online 31 May 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Joshua B. Wechsler, Ikuo Hirano
The scientific basis and the clinical application of monoclonal antibody therapies that target specific immunologic pathways for eosinophilic gastrointestinal diseases (EGIDs) are areas of active interest. There is a growing recognition of a subset of patients with eosinophilic esophagitis, or EoE, whose disease does not respond well to topical steroids or elimination diets. In addition, long-term use of corticosteroids presents risks. Systemic therapy with a biologic agent offers potential advantages as a global approach that could limit the need for multiple, locally active medical therapies and allergen avoidance. The identification of novel biologic strategies is ongoing, and the recent validation of instruments and outcome measures to assess disease activity has proved essential in demonstrating efficacy. Studies using biologics that target IL-13 pathways in the treatment of EoE have demonstrated substantial promise.



https://ift.tt/2JiM8j7

A novel soft tissue prediction methodology for orthognathic surgery based on probabilistic finite element modelling

Knoops, PGM; Borghi, A; Ruggiero, F; Badiali, G; Bianchi, A; Marchetti, C; Rodriguez-Florez, N; ... Schievano, S; + view all Knoops, PGM; Borghi, A; Ruggiero, F; Badiali, G; Bianchi, A; Marchetti, C; Rodriguez-Florez, N; Breakey, RWF; Jeelani, O; Dunaway, DJ; Schievano, S; - view fewer (2018) A novel soft tissue prediction methodology for orthognathic surgery based on probabilistic finite element modelling. PLoS One , 13 (5) , Article e0197209. 10.1371/journal.pone.0197209 . Green open access

https://ift.tt/2sv8IKO

Cerebral microbleeds and intracranial haemorrhage risk in patients anticoagulated for atrial fibrillation after acute ischaemic stroke or transient ischaemic attack (CROMIS-2): a multicentre observational cohort study

Wilson, D; Ambler, G; Shakeshaft, C; Brown, MM; Charidimou, A; Salman, RA-S; Lip, GYH; ... Werring, DJ; + view all Wilson, D; Ambler, G; Shakeshaft, C; Brown, MM; Charidimou, A; Salman, RA-S; Lip, GYH; Cohen, H; Banerjee, G; Houlden, H; White, MJ; Yousry, TA; Harkness, K; Flossmann, E; Smyth, N; Shaw, LJ; Warburton, E; Muir, KW; Jager, HR; Werring, DJ; - view fewer (2018) Cerebral microbleeds and intracranial haemorrhage risk in patients anticoagulated for atrial fibrillation after acute ischaemic stroke or transient ischaemic attack (CROMIS-2): a multicentre observational cohort study. The Lancet Neurology , 17 (6) pp. 539-547. 10.1016/S1474-4422(18)30145-5 . Green open access

https://ift.tt/2IYjdRT

A Structure and Durability Comparison of Membrane Electrode Assembly Fabrication Methods: Self-Assembled Versus Hot-Pressed

Hack, J; Heenan, TMM; Iacoviello, F; Mansor, N; Meyer, Q; Shearing, P; Brandon, N; Hack, J; Heenan, TMM; Iacoviello, F; Mansor, N; Meyer, Q; Shearing, P; Brandon, N; Brett, DJL; - view fewer (2018) A Structure and Durability Comparison of Membrane Electrode Assembly Fabrication Methods: Self-Assembled Versus Hot-Pressed. Journal of The Electrochemical Society , 165 (6) F3045-F3052. 10.1149/2.0051806jes . Green open access

https://ift.tt/2sv8xz8

A Stone-type Duality Theorem for Separation Logic Via its Underlying Bunched Logics

Docherty, S; Pym, D; (2018) A Stone-type Duality Theorem for Separation Logic Via its Underlying Bunched Logics. Electronic Notes in Theoretical Computer Science , 336 pp. 101-118. 10.1016/j.entcs.2018.03.018 . Green open access

https://ift.tt/2IZFqiG

A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome

Di Gioia, SA; Connors, S; Matsunami, N; Cannavino, J; Rose, MF; Gilette, NM; Artoni, P; ... Hutchinson, EB; + view all Di Gioia, SA; Connors, S; Matsunami, N; Cannavino, J; Rose, MF; Gilette, NM; Artoni, P; De Macena Sobreira, NL; Chan, WM; Webb, BD; Robson, CD; Cheng, L; Van Ryzin, C; Ramirez-Martinez, A; Mohassel, P; Leppert, M; Scholand, MB; Grunseich, C; Ferreira, CR; Hartman, T; Hayes, IM; Morgan, T; Markie, DM; Fagiolini, M; Swift, A; Chines, PS; Speck-Martins, CE; Collins, FS; Jabs, EW; Bönnemann, CG; Olson, EN; Carey, JC; Robertson, SP; Manoli, I; Engle, EC; Andrews, CV; Barry, BJ; Hunter, DG; Mackinnon, SE; Shaaban, S; Erazo, M; Frempong, T; Hao, K; Naidich, TP; Rucker, JC; Zhang, Z; Biesecker, BB; Bonnycastle, LL; Brewer, CC; Brooks, BP; Butman, JA; Chien, WW; Farrell, K; FitzGibbon, EJ; Gropman, AL; Hutchinson, EB; - view fewer (2017) A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome. Nature Communications , 8 , Article 16077. 10.1038/ncomms16077 . Green open access

https://ift.tt/2H6Wg9C

Neuroconductor: an R platform for medical imaging analysis

Muschelli, J; Gherman, A; Fortin, J-P; Avants, B; Whitcher, B; Clayden, JD; Caffo, BS; Muschelli, J; Gherman, A; Fortin, J-P; Avants, B; Whitcher, B; Clayden, JD; Caffo, BS; Crainiceanu, CM; - view fewer (2018) Neuroconductor: an R platform for medical imaging analysis. Biostatistics , Article kxx068. 10.1093/biostatistics/kxx068 .

https://ift.tt/2IZFkHQ

Sexual abuse and psychosis: The security of research findings

Bebbington, PE; (2018) Sexual abuse and psychosis: The security of research findings. Schizophrenia Research 10.1016/j.schres.2018.04.038 . (In press).

https://ift.tt/2H6UrJT

Metabolites predict lesion formation and severity in relapsing-remitting multiple sclerosis

Klauser, AM; Wiebenga, OT; Eijlers, AJ; Schoonheim, MM; Uitdehaag, BM; Barkhof, F; Pouwels, PJ; Klauser, AM; Wiebenga, OT; Eijlers, AJ; Schoonheim, MM; Uitdehaag, BM; Barkhof, F; Pouwels, PJ; Geurts, JJ; - view fewer (2018) Metabolites predict lesion formation and severity in relapsing-remitting multiple sclerosis. Multiple Sclerosis Journal , 24 (4) pp. 491-500. 10.1177/1352458517702534 . Green open access

https://ift.tt/2IZTSXN

Associations between the use of herbal medicines and adverse pregnancy outcomes in rural Malawi: a secondary analysis of randomised controlled trial data

Zamawe, C; King, C; Jennings, H; Fottrell, E; (2018) Associations between the use of herbal medicines and adverse pregnancy outcomes in rural Malawi: a secondary analysis of randomised controlled trial data. BMC Complementary and Alternative Medicine , 18 , Article 166. 10.1186/s12906-018-2203-z . Green open access

https://ift.tt/2H7uXvQ

Conservation genomics reveals possible illegal trade routes and admixture across pangolin lineages in Southeast Asia

Nash, HC; Wirdateti, ; Low, GW; Choo, SW; Chong, JL; Semiadi, G; Hari, R; ... Rheindt, FE; + view all Nash, HC; Wirdateti, ; Low, GW; Choo, SW; Chong, JL; Semiadi, G; Hari, R; Sulaiman, MH; Turvey, ST; Evans, TA; Rheindt, FE; - view fewer (2018) Conservation genomics reveals possible illegal trade routes and admixture across pangolin lineages in Southeast Asia. Conservation Genetics (In press).

https://ift.tt/2kFovn4

Dynamic behaviour in nicotinate-bridged binuclear ruthenium(IV) complexes

Tocher, DA; Steed, J; (2018) Dynamic behaviour in nicotinate-bridged binuclear ruthenium(IV) complexes. Polyhedron , 147 pp. 152-155. 10.1016/j.poly.2018.03.025 . (In press).

https://ift.tt/2sts0QN

Claiming Resources, Honoring Debts: Miners, Herders, and the Masters of the Land in Mongolia

Empson, RA; (2017) Claiming Resources, Honoring Debts: Miners, Herders, and the Masters of the Land in Mongolia. Ethnos (In press).

https://ift.tt/2IYbjYZ

Massive Silicone Oil Migration into the Subconjunctival Space: A Leakage Mechanism Dilemma

Purpose: To report a case in which an early, massive silicone oil migration into the subconjunctival space occurred in a patient after sutureless vitrectomy with the presence of a previously implanted pars plana glaucoma drainage device. Case Report: An 80-year-old man presented with neovascular glaucoma secondary to a proliferative diabetic retinopathy in his left eye. After an intracamerular bevacizumab injection and panretinal photocoagulation, a 23-gauge pars plana vitrectomy (PPV) combined with a superotemporal Ahmed pars plana glaucoma valve implantation was performed. Afterwards, the patient underwent a new 23-gauge PPV for a dense vitreous hemorrhage. Intravitreal 1,000 centistokes silicone oil was placed to prevent recurrent intraocular bleeding. No sutures were performed. In the first postoperative month, a massive migration of silicone oil into the 360° subconjunctival space was noted until no intraocular silicone oil was observed. Conclusions: We discuss the possible leakage mechanisms in this particular case.
Case Rep Ophthalmol 2018;9:310–314

https://ift.tt/2kEfqLh

Apatinib for Esophagus Cancer

Condition:   Esophagus Cancer
Intervention:   Drug: Apatinib
Sponsor:   Affiliated Hospital of North Sichuan Medical College
Not yet recruiting

https://ift.tt/2JiACnT

Prof. dr. MirkoToš: Obituary

Publication date: July 2018
Source:International Journal of Pediatric Otorhinolaryngology, Volume 110
Author(s): Janez Rebol




https://ift.tt/2JlLdOM

Undifferentiated Pleomorphic Sarcoma of Pancreas: A Case Report and Review of the Literature for the Last Updates

The most prevalent type of soft tissue sarcoma is undifferentiated pleomorphic sarcoma (UPS) or previously known as malignant fibrous histiocytoma. It accounts over 20% of all soft tissue sarcomas and occurs most frequently in the extremities, trunk, and retroperitoneum. However, it has been rarely observed in the digestive system. Pancreas sarcoma represents less than 1% of all pancreatic tumors, and primary UPS of the pancreas is even rarer. It exhibits high recurrence and poor prognosis. In this case, a 72-year-old woman with a UPS tumor which was located in the pancreas head and neck without adhesion to the retroperitoneum will be discussed.

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Infection Rates After Colonoscopy, Endoscopy at US Specialty Centers Are Far Higher Than Previously Thought

The rates of infection following colonoscopies and upper-GI endoscopies performed at U.S. outpatient specialty centers are far higher than previously believed, according to a Johns Hopkins study published online this month in the journal Gut.

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Labeling Morphine Milligram Equivalents on Opioid Packaging: a Potential Patient Safety Intervention

Abstract

Purpose of Review

Given that the primary cause of overdose death in the USA is related to prescribed opioids, one potential strategy to improve awareness and decrease morbidity and/or mortality could include improved labeling. Specific patient populations which significantly struggle with adverse outcomes related to opioid abuse are seen in palliative care, chronic pain, and acute pain treatment settings.

Recent Findings

An unexplored option for improving the healthcare quality and safety for patients currently prescribed opioids would be to require pharmaceutical companies to provide a morphine milligram equivalent (MME) on opioid packaging. Some limitations to MME conversions include equianalgesic conversions being estimates at best and may not account for variations in genetics and pharmacokinetics. Changing opioid labeling requirements is feasible as it falls under the purview of the US Food and Drug Administration (FDA), which has been mandated to provide mechanisms to reduce or to minimize overdoses related to opioid prescriptions.

Summary

Labeling opioid packaging with MME per dose will promote clearer communication about opioid strength between patients and physicians. Labeling MME on packaging could help prevent prescriber errors.

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Polypharmacy Is Associated With Higher Frailty Risk in Older People: An 8-Year Longitudinal Cohort Study

Veronese, N; Stubbs, B; Noale, M; Solmi, M; Pilotto, A; Vaona, A; Demurtas, J; ... Maggi, S; + view all Veronese, N; Stubbs, B; Noale, M; Solmi, M; Pilotto, A; Vaona, A; Demurtas, J; Mueller, C; Huntley, J; Crepaldi, G; Maggi, S; - view fewer (2017) Polypharmacy Is Associated With Higher Frailty Risk in Older People: An 8-Year Longitudinal Cohort Study. Journal of the American Medical Directors Association , 18 (7) pp. 624-628. 10.1016/j.jamda.2017.02.009 . Green open access

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The role of family literacy classes in demystifying school literacies and developing closer parent–school relations

Swain, J; Cara, O; (2018) The role of family literacy classes in demystifying school literacies and developing closer parent–school relations. Cambrdige Journal of Education 10.1080/0305764X.2018.1461809 . (In press).

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Identification of rare nonsynonymous variants in SYNE1/CPG2 in bipolar affective disorder

Sharp, SI; Lange, J; Kandaswamy, R; Daher, M; Anjorin, A; Bass, NJ; McQuillin, A; (2017) Identification of rare nonsynonymous variants in SYNE1/CPG2 in bipolar affective disorder. Psychiatric Genetics , 27 (3) pp. 81-88. 10.1097/YPG.0000000000000166 . Green open access

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Structural white matter changes in adults and children with posttraumatic stress 3 disorder: a systematic review and meta-analysis

Siehl, S; King, JA; Burgess, N; Flor, H; Nees, F; (2018) Structural white matter changes in adults and children with posttraumatic stress 3 disorder: a systematic review and meta-analysis. NeuroImage: Clinical (In press).

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How shape and internal structure affect the magnetic properties of anisometric magnetite nanoparticles

Gavilan, H; Posth, O; Bogart, LK; Steinhoff, U; Gutierrez, L; Puerto Morales, M; (2017) How shape and internal structure affect the magnetic properties of anisometric magnetite nanoparticles. Acta Materialia , 125 pp. 416-424. 10.1016/j.actamat.2016.12.016 . Green open access

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The additional lateralizing and localizing value of the postictal EEG in frontal lobe epilepsy

Whitehead, K; Gollwitzer, S; Millward, H; Wehner, T; Scott, C; Diehl, B; (2016) The additional lateralizing and localizing value of the postictal EEG in frontal lobe epilepsy. Clinical Neurophysiology , 127 (3) pp. 1774-1780. 10.1016/j.clinph.2015.11.050 . Green open access

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Southeast Greenland Winter Precipitation Strongly Linked to the Icelandic Low Position

Berdahl, M; Rennermalm, A; Hammann, A; Mioduszweski, J; Hameed, S; Tedesco, M; Stroeve, J; ... McConnell, J; + view all Berdahl, M; Rennermalm, A; Hammann, A; Mioduszweski, J; Hameed, S; Tedesco, M; Stroeve, J; Mote, T; Koyama, T; McConnell, J; - view fewer (2018) Southeast Greenland Winter Precipitation Strongly Linked to the Icelandic Low Position. Journal of Climate , 31 (11) pp. 4483-4500. 10.1175/JCLI-D-17-0622.1 .

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Enhancing the Magnetic Heating Capacity of Iron Oxide Nanoparticles through Their Postproduction Incorporation into Iron Oxide-Gold Nanocomposites

Bell, G; Bogart, LK; Southern, P; Olivo, M; Pankhurst, QA; Parkin, IP; (2017) Enhancing the Magnetic Heating Capacity of Iron Oxide Nanoparticles through Their Postproduction Incorporation into Iron Oxide-Gold Nanocomposites. European Journal of Inorganic Chemistry (18) pp. 2386-2395. 10.1002/ejic.201601432 . Green open access

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Serendipitous isolation of a disappearing conformational polymorph of succinic acid challenges computational polymorph prediction

Lucaioli, P; Nauha, E; Gimondi, I; Price, LS; Guo, R; Iuzzolino, L; Singh, I; ... Blagden, N; + view all Lucaioli, P; Nauha, E; Gimondi, I; Price, LS; Guo, R; Iuzzolino, L; Singh, I; Salvalaglio, M; Price, SL; Blagden, N; - view fewer (2018) Serendipitous isolation of a disappearing conformational polymorph of succinic acid challenges computational polymorph prediction. CrystEngComm 10.1039/C8CE00625C . (In press).

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Reference tracts and generative models for brain white matter tractography

Muñoz Maniega, S; Bastin, ME; Deary, IJ; Wardlaw, JM; Clayden, JD; (2017) Reference tracts and generative models for brain white matter tractography. Journal of Imaging , 4 (1) p. 8. 10.3390/jimaging4010008 . Green open access

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Accurate Delineation of Glioma Infiltration by Advanced PET/MR Neuro-Imaging (FRONTIER Study): A Diagnostic Study Protocol

Verburg, N; Pouwels, PJW; Boellaard, R; Barkhof, F; Hoekstra, OS; Reijneveld, JC; Vandertop, WP; ... Hamer, PCDW; + view all Verburg, N; Pouwels, PJW; Boellaard, R; Barkhof, F; Hoekstra, OS; Reijneveld, JC; Vandertop, WP; Wesseling, P; Hamer, PCDW; - view fewer (2016) Accurate Delineation of Glioma Infiltration by Advanced PET/MR Neuro-Imaging (FRONTIER Study): A Diagnostic Study Protocol. Neurosurgery , 79 (4) pp. 535-540. 10.1227/NEU.0000000000001355 . Green open access

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Neutralization and homophony avoidance in phonological learning

Yin, SH; White, JC; (2018) Neutralization and homophony avoidance in phonological learning. Cognition (In press).

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Rapid Imaging of Tumor Cell Death In Vivo Using the C2A Domain of Synaptotagmin-I

Neves, AA; Xie, B; Fawcett, S; Alam, IS; Witney, TH; de Backer, MM; Summers, J; ... Brindle, KM; + view all Neves, AA; Xie, B; Fawcett, S; Alam, IS; Witney, TH; de Backer, MM; Summers, J; Hughes, W; McGuire, S; Soloviev, D; Miller, J; Howat, WJ; Hu, D-E; Rodrigues, TB; Lewis, DY; Brindle, KM; - view fewer (2017) Rapid Imaging of Tumor Cell Death In Vivo Using the C2A Domain of Synaptotagmin-I. Journal of Nuclear Medicine , 58 (6) pp. 881-887. 10.2967/jnumed.116.183004 . Green open access

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Age constraints on intra-formational unconformities in Upper Jurassic-Lower Cretaceous carbonates in northeast Turkey; geodynamic and hydrocarbon implications

Vincent, SJ; Guo, L; Flecker, R; BouDagher-Fadel, MK; Ellam, RM; Kandemir, R; (2018) Age constraints on intra-formational unconformities in Upper Jurassic-Lower Cretaceous carbonates in northeast Turkey; geodynamic and hydrocarbon implications. Marine and Petroleum Geology , 91 pp. 639-657. 10.1016/j.marpetgeo.2018.01.011 .

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Barreras interaccionales en aulas multilingües: una aproximación crítica a la comunicación intercultural

Perez-Milans, MPM; Martin-Rojo, L; (2007) Barreras interaccionales en aulas multilingües: una aproximación crítica a la comunicación intercultural. Cultura, Lenguaje Y Representación / Culture, Language and Representation , 4 pp. 203-226. 10.6035/CLR .

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Randomized controlled phase III trial of adjuvant chemoimmunotherapy with activated cytotoxic T cells and dendritic cells from regional lymph nodes of patients with lung cancer

Abstract

Randomized controlled trial of adjuvant chemoimmunotherapy for lung cancer indicated a significant advantage in patients receiving immunotherapy. Herein we report the final results and immunological analysis with a median follow-up of 59.6 months. Patients with post-surgical lung cancer were randomly designated to receive either chemoimmunotherapy (group A, immunotherapy arm) or chemotherapy (group B, control arm). The immunotherapy comprised the adoptive transfer of autologous activated killer T cells and dendritic cells (AKT–DC). The 2- and 5-year overall survival (OS) rates were 96.0 and 69.4% in group A and 64.7 and 45.1% in group B, respectively. Multivariate analysis results revealed that the hazard ratio was 0.439. The 2- and 5-year recurrence-free survival rates were 70.0 and 57.9% in group A and 43.1 and 31.4% in group B, respectively. Subgroup analysis for the OS between treatment groups indicated that younger patients (≤ 55 years: HR 0.098), males (HR 0.474), patients with adenocarcinoma (HR 0.479), patients with stage III cancer (HR 0.399), and those who did not receive preoperative chemotherapy (HR 0.483) had lower HRs than those in the other groups. Immunological analysis of cell surface markers in regional lymph nodes of subjects receiving immunotherapy indicated that the CD8⁺/CD4⁺ T-cell ratio was elevated in survivors. Patients with non-small-cell lung cancer benefited from adoptive cellular immunotherapy as an adjuvant to surgery. Patients with stage III cancer, those with adenocarcinoma, and those not receiving preoperative chemotherapy were good candidates. Lastly, cytotoxic T cells were important for a favorable chemoimmunotherapy outcome.

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Case 17-2018: A 40-Year-Old Woman with Leg Swelling and Abdominal Distention and Pain

Presentation of Case. Dr. Molly E. Wolf (Medicine): A 40-year-old woman was evaluated at this hospital because of progressive edema of the legs, as well as abdominal distention and pain. The patient had been in good health until approximately 10 months before this evaluation, when episodes of pain…

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A measurement of CMB cluster lensing with SPT and DES year 1 data

Baxter, EJ; Raghunathan, S; Crawford, TM; Fosalba, P; Hou, Z; Holder, GP; Omori, Y; ... Zuntz, J; + view all Baxter, EJ; Raghunathan, S; Crawford, TM; Fosalba, P; Hou, Z; Holder, GP; Omori, Y; Patil, S; Rozo, E; Abbott, TMC; Annis, J; Aylor, K; Benoit-Levy, A; Benson, BA; Bertin, E; Bleem, L; Buckley-Geer, E; Burke, DL; Carlstrom, J; Rosell, AC; Kind, MC; Carretero, J; Chang, CL; Cho, H-M; Crites, AT; Crocce, M; Cunha, CE; da Costa, LN; D'Andrea, CB; Davis, C; de Haan, T; Desai, S; Dietrich, JP; Dobbs, MA; Dodelson, S; Doel, P; Drlica-Wagner, A; Estrada, J; Everett, WB; Neto, AF; Flaugher, B; Frieman, J; Garcia-Bellido, J; George, EM; Gaztanaga, E; Giannantonio, T; Gruen, D; Gruendl, RA; Gschwend, J; Gutierrez, G; Halverson, NW; Harrington, NL; Hartley, WG; Holzapfel, WL; Honscheid, K; Hrubes, JD; Jain, B; James, DJ; Jarvis, M; Jeltema, T; Knox, L; Krause, E; Kuehn, K; Kuhlmann, S; Kuropatkin, N; Lahav, O; Lee, AT; Leitch, EM; Li, TS; Lima, M; Luong-Van, D; Manzotti, A; March, M; Marrone, DP; Marshall, JL; Martini, P; McMahon, JJ; Melchior, P; Menanteau, F; Meyer, SS; Miller, CJ; Miquel, R; Mocanu, LM; Mohr, JJ; Natoli, T; Nord, B; Ogando, RLC; Padin, S; Plazas, AA; Pryke, C; Rapetti, D; Reichardt, CL; Romer, AK; Roodman, A; Ruhl, JE; Rykoff, E; Sako, M; Sanchez, E; Sayre, JT; Scarpine, V; Schaffer, KK; Schindler, R; Schubnell, M; Sevilla-Noarbe, I; Shirokoff, E; Smith, M; Smith, RC; Soares-Santos, M; Sobreira, F; Staniszewski, Z; Stark, A; Story, K; Suchyta, E; Tarle, G; Thomas, D; Troxel, MA; Vanderlinde, K; Vieira, JD; Walker, AR; Williamson, R; Zhang, Y; Zuntz, J; - view fewer (2018) A measurement of CMB cluster lensing with SPT and DES year 1 data. Monthly Notices of the Royal Astronomical Society , 476 (2) pp. 2674-2688. 10.1093/mnras/sty305 . Green open access

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Brentuximab vedotin prior to allogeneic stem cell transplantation in Hodgkin lymphoma: a report from the EBMT Lymphoma Working Party

Bazarbachi, A; Boumendil, A; Finel, H; Mohty, M; Castagna, L; Peggs, KS; Blaise, D; ... Sureda, A; + view all Bazarbachi, A; Boumendil, A; Finel, H; Mohty, M; Castagna, L; Peggs, KS; Blaise, D; Afanasyev, B; Diez-Martin, JL; Sierra, J; Bloor, A; Martinez, C; Robinson, S; Malladi, R; El-Cheikh, J; Corradini, P; Montoto, S; Dreger, P; Sureda, A; - view fewer (2018) Brentuximab vedotin prior to allogeneic stem cell transplantation in Hodgkin lymphoma: a report from the EBMT Lymphoma Working Party. British Journal of Haematology , 181 (1) pp. 86-96. 10.1111/bjh.15152 .

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Unveiling the Dynamical State of Massive Clusters through the ICL Fraction

Jimenez-Teja, Y; Dupke, R; Benitez, N; Koekemoer, AM; Zitrin, A; Umetsu, K; Ziegler, BL; ... Zheng, W; + view all Jimenez-Teja, Y; Dupke, R; Benitez, N; Koekemoer, AM; Zitrin, A; Umetsu, K; Ziegler, BL; Frye, BL; Ford, H; Bouwens, RJ; Bradley, LD; Broadhurst, T; Coe, D; Donahue, M; Graves, GJ; Grillo, C; Infante, L; Jouvel, S; Kelson, DD; Lahav, O; Lazkoz, R; Lemze, D; Maoz, D; Medezinski, E; Melchior, P; Meneghetti, M; Mercurio, A; Merten, J; Molino, A; Moustakas, LA; Nonino, M; Ogaz, S; Riess, AG; Rosati, P; Sayers, J; Seitz, S; Zheng, W; - view fewer (2018) Unveiling the Dynamical State of Massive Clusters through the ICL Fraction. The Astrophysical Journal , 857 (2) , Article 79. 10.3847/1538-4357/aab70f . Green open access

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Predicting opportunities to increase utilization of laparoscopy for rectal cancer

Keller, DS; Qiu, J; Senagore, AJ; (2017) Predicting opportunities to increase utilization of laparoscopy for rectal cancer. Surgical Endoscopy , 32 (3) pp. 1556-1563. 10.1007/s00464-017-5844-y .

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Role of Emergency Laparoscopic Colectomy for Colorectal Cancer: A Population-Based Study in England

Vallance, AE; Keller, DS; Hill, J; Braun, M; Kuryba, A; van der Meulen, J; Walker, K; Vallance, AE; Keller, DS; Hill, J; Braun, M; Kuryba, A; van der Meulen, J; Walker, K; Chand, M; - view fewer (2018) Role of Emergency Laparoscopic Colectomy for Colorectal Cancer: A Population-Based Study in England. Annals of Surgery 10.1097/SLA.0000000000002752 . (In press).

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ERGs on the brain: the benefits of simultaneous flash retinal and cortical responses in paediatric cerebral visual impairment

Handley, SE; Thompson, DA; Prise, KL; Liasis, A; (2018) ERGs on the brain: the benefits of simultaneous flash retinal and cortical responses in paediatric cerebral visual impairment. Documenta Ophthalmologica 10.1007/s10633-018-9631-4 . (In press). Green open access

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A virally encoded de-sumoylase activity is required for cytomegalovirus reactivation from latency

Poole, E; Lau, J; Kew, V; Murray, M; Stamminger, T; Sinclair, J; Reeves, M; (2018) A virally encoded de-sumoylase activity is required for cytomegalovirus reactivation from latency. Cell Reports (In press).

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What's in a Name? Possible Ways Forward in the Macedonian Name Dispute

Fidanovski, K; What's in a Name? Possible Ways Forward in the Macedonian Name Dispute. Slovo , 31 (1) , Article 2. 10.14324/111.0954-6839.073 . Green open access

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Multichannel visual evoked potentials in the assessment of visual pathways in children with marked brain abnormalities

Handley, SE; Liasis, AC; (2017) Multichannel visual evoked potentials in the assessment of visual pathways in children with marked brain abnormalities. Journal of American Association for Pediatric Ophthalmology and Strabismus (AAPOS) , 21 (1) pp. 52-56. 10.1016/j.jaapos.2016.10.003 . Green open access

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Impaired motility in Barrett's esophagus: A study using high-resolution manometry with physiologic challenge

Sanagapalli, S; Emmanuel, A; Leong, R; Kerr, S; Lovat, L; Haidry, R; Banks, M; ... Sweis, R; + view all Sanagapalli, S; Emmanuel, A; Leong, R; Kerr, S; Lovat, L; Haidry, R; Banks, M; Graham, D; Raeburn, A; Zarate-Lopez, N; Sweis, R; - view fewer (2018) Impaired motility in Barrett's esophagus: A study using high-resolution manometry with physiologic challenge. Neurogastroenterol Motil , Article e13330. 10.1111/nmo.13330 . (In press).

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Assessment of medical devices: the Emperor’s new clothes: Author reply

Sharma, RA; Fumi, L; Audisio, RA; Denys, A; Wood, BJ; Pignatti, F; (2018) Assessment of medical devices: the Emperor's new clothes: Author reply. [Letter]. British Journal of Radiology , 91 , Article 20180310. 10.1259/bjr.20180310 . (In press).

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Obesity is not just elevated adiposity, it is also a state of metabolic perturbation

Wells, JCK; (2017) Obesity is not just elevated adiposity, it is also a state of metabolic perturbation. Behavioral and Brain Sciences , 40 , Article e130. 10.1017/S0140525X16001552 . Green open access

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Using flawed, uncertain, proximate and sparse (FUPS) data in the context of complexity: learning from the case of child mental health

Wolpert, MR; Rutter, H; (2018) Using flawed, uncertain, proximate and sparse (FUPS) data in the context of complexity: learning from the case of child mental health. BMC Medicine (In press).

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Disentangling the visual, motor and representational effects of vestibular input

Abekawa, N; Ferrè, ER; Gallagher, M; Gomi, H; Haggard, P; (2018) Disentangling the visual, motor and representational effects of vestibular input. Cortex , 104 pp. 46-57. 10.1016/j.cortex.2018.04.003 .

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Majority of adolescents with depression and anxiety not reliably improved at end of treatment: What should we tell the children?

Childs, J; Wolpert, MR; Zamperoni, V; Napoleone, E; Bear, H; (2018) Majority of adolescents with depression and anxiety not reliably improved at end of treatment: What should we tell the children? BjPsych Open (In press).

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Editorial to issue 31.1

Allison, K; Editorial to issue 31.1. Slovo , 31 (1) , Article 1. 10.14324/111.0954-6839.078 . Green open access

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Language as description, indication, and depiction

Ferrara, L; Hodge, G; (2018) Language as description, indication, and depiction. Frontiers in Psychology , 9 , Article 716. 10.3389/fpsyg.2018.00716 . Green open access

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Dihydrogen: Vs. hydrogen bonding in the solvation of ammonia borane by tetrahydrofuran and liquid ammonia

Ingram, DJ; Headen, TF; Skipper, NT; Callear, SK; Billing, M; Sella, A; (2018) Dihydrogen: Vs. hydrogen bonding in the solvation of ammonia borane by tetrahydrofuran and liquid ammonia. Physical Chemistry Chemical Physics , 20 (17) pp. 12200-12209. 10.1039/c7cp08220g . Green open access

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Effects of exposure to bodies of different sizes on perception of and satisfaction with own body size: Two randomized studies

Bould, H; Carnegie, R; Allward, H; Bacon, E; Lambe, E; Sapseid, M; Button, KS; ... Munafò, MR; + view all Bould, H; Carnegie, R; Allward, H; Bacon, E; Lambe, E; Sapseid, M; Button, KS; Lewis, G; Skinner, A; Broome, MR; Park, R; Harmer, CJ; Penton-Voak, IS; Munafò, MR; - view fewer (2018) Effects of exposure to bodies of different sizes on perception of and satisfaction with own body size: Two randomized studies. Royal Society Open Science , 5 (5) , Article 171387. 10.1098/rsos.171387 . Green open access

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