Bloxsom, J; (2016) Thermal and Magnetic Studies of Spin Ice Compounds. Doctoral thesis, UCL (University College London). Green open access
http://ift.tt/2gHlthR
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Παρασκευή 25 Νοεμβρίου 2016
Thermal and Magnetic Studies of Spin Ice Compounds
Modelling the structure of Zr-rich Pb(Zr1-xTix)O-3, x=0.4 by a multiphase approach
Bogdanov, A; Mysovsky, A; Pickard, CJ; Kimmel, AV; (2016) Modelling the structure of Zr-rich Pb(Zr1-xTix)O-3, x=0.4 by a multiphase approach. Physical Chemistry Chemical Physics , 18 (40) pp. 28316-28324. 10.1039/c6cp04976a .
http://ift.tt/2gtWN9K
Foreword: Special issue-geriatric drug therapy
Gul, MO; Liu, F; Hughes, C; (2016) Foreword: Special issue-geriatric drug therapy. International Journal of Pharmaceutics , 512 (2) p. 331. 10.1016/j.ijpharm.2016.08.023 .
http://ift.tt/2gHdKAJ
Hypertensive Disorders of Pregnancy and Offspring Cardiac Structure and Function in Adolescence
Timpka, S; Macdonald-Wallis, C; Hughes, AD; Chaturvedi, N; Franks, PW; Lawlor, DA; Fraser, A; (2016) Hypertensive Disorders of Pregnancy and Offspring Cardiac Structure and Function in Adolescence. Journal of the American Heart Association , 5 (11) , Article e003906. 10.1161/JAHA.116.003906 . Green open access
http://ift.tt/2gtRbfH
The Genetics of Coronary Heart Disease across Ethnicities and in those with Type 2 Diabetes
Beaney, KE; (2016) The Genetics of Coronary Heart Disease across Ethnicities and in those with Type 2 Diabetes. Doctoral thesis, UCL (University College London). Green open access
http://ift.tt/2gHcduj
Mean-field energy-level shifts and dielectric properties of strongly polarized Rydberg gases
Zhelyazkova, V; Jirschik, R; Hogan, SD; (2016) Mean-field energy-level shifts and dielectric properties of strongly polarized Rydberg gases. Physical Review A: Atomic, Molecular and Optical Physics , 94 (5) , Article 053418. 10.1103/PhysRevA.94.053418 . Green open access
http://ift.tt/2gtUCD2
The Inter-relationship of Adolescent Unhappiness and Parental Mental Distress
Webb, EA; Panico, L; Becares, L; McMunn, A; Kelly, Y; Sacker, A; (2016) The Inter-relationship of Adolescent Unhappiness and Parental Mental Distress. Journal of Adolescent Health 10.1016/j.jadohealth.2016.10.001 . (In press). Green open access
http://ift.tt/2gtY2G2
Shifting human resources for health in the context of ART provision: qualitative and quantitative findings from the Lablite baseline study
Nkhata, MJ; Muzambi, M; Ford, D; Chan, AK; Abongomera, G; Namata, H; Mambule, I; Nkhata, MJ; Muzambi, M; Ford, D; Chan, AK; Abongomera, G; Namata, H; Mambule, I; South, A; Revill, P; Grundy, C; Mabugu, T; Chiwaula, L; Hakim, J; Kityo, C; Reid, A; Katabira, E; Sodhi, S; Gilks, CF; Gibb, DM; Seeley, J; Cataldo, F; Lablite team, .; - view fewer (2016) Shifting human resources for health in the context of ART provision: qualitative and quantitative findings from the Lablite baseline study. BMC Health Services Research , 16 , Article 660. 10.1186/s12913-016-1891-7 . Green open access
http://ift.tt/2gHc89U
Change in commute mode and BMI: longitudinal, prospective evidence from UK Biobank
Flint, E; Webb, EA; Cummins, S; (2016) Change in commute mode and BMI: longitudinal, prospective evidence from UK Biobank. Lancet Public Health 10.1016/S2468-2667(16)30006-8 . (In press). Green open access
http://ift.tt/2gtRas9
Multiscale optical patterning: using micro and nano periodic structures to create novel optical devices with applications to biosensing
Bailey, J; (2016) Multiscale optical patterning: using micro and nano periodic structures to create novel optical devices with applications to biosensing. Doctoral thesis, UCL (University College London).
http://ift.tt/2gHc7To
Ephedrine treatment for autoimmune myasthenia gravis
Lipka, AF; Vrinten, C; van Zwet, EW; Schimmel, KJM; Cornel, MC; Kuijpers, MR; Hekster, YA; Lipka, AF; Vrinten, C; van Zwet, EW; Schimmel, KJM; Cornel, MC; Kuijpers, MR; Hekster, YA; Weinreich, SS; Verschuuren, JJGM; - view fewer (2016) Ephedrine treatment for autoimmune myasthenia gravis. Neuromuscular Disorders 10.1016/j.nmd.2016.11.009 . (In press).
http://ift.tt/2gtTwHr
What are the major factors behind the apparent policy failure in relation to the employer role in 14-19 education and training?
Andressen, EM; (2016) What are the major factors behind the apparent policy failure in relation to the employer role in 14-19 education and training? Doctoral thesis, UCL (University College London). Green open access
http://ift.tt/2gHcai7
Implementation of antiretroviral therapy for life in pregnant/breastfeeding HIV+ women (Option B+) alongside rollout and changing guidelines for ART initiation in rural Zimbabwe: the Lablite Project experience
Ford, D; Muzambi, M; Nkhata, MJ; Abongomera, A; Joseph, S; Ndlovu, M; Mabugu, T; Ford, D; Muzambi, M; Nkhata, MJ; Abongomera, A; Joseph, S; Ndlovu, M; Mabugu, T; Grundy, C; Chan, AK; Cataldo, F; Kityo, C; Seeley, J; Katabira, E; Gilks, CF; Reid, A; Hakim, J; Gibb, DM; Lablite Team, .; - view fewer (2017) Implementation of antiretroviral therapy for life in pregnant/breastfeeding HIV+ women (Option B+) alongside rollout and changing guidelines for ART initiation in rural Zimbabwe: the Lablite Project experience. JAIDS: Journal of Acquired Immune Deficiency Syndromes (In press).
http://ift.tt/2gtVCHv
Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis
Taylor, AE; Martin, RM; Geybels, MS; Stanford, JL; Shui, I; Eeles, R; Easton, D; Taylor, AE; Martin, RM; Geybels, MS; Stanford, JL; Shui, I; Eeles, R; Easton, D; Kote-Jarai, Z; Amin Al Olama, A; Benlloch, S; Muir, K; Giles, GG; Wiklund, F; Gronberg, H; Haiman, CA; Schleutker, J; Nordestgaard, BG; Travis, RC; Neal, D; Pashayan, N; Khaw, KT; Blot, W; Thibodeau, S; Maier, C; Kibel, AS; Cybulski, C; Cannon-Albright, L; Brenner, H; Park, J; Kaneva, R; Batra, J; Teixeira, MR; Pandha, H; PRACTICAL Consortium, .; Donovan, J; Munafò, MR; - view fewer (2017) Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis. International Journal of Cancer , 140 (2) pp. 322-328. 10.1002/ijc.30462 . Green open access
http://ift.tt/2gHjsTd
Essays on Macroeconomics, Fiscal Policy and Income Mobility
Alloza Frutos, M; (2016) Essays on Macroeconomics, Fiscal Policy and Income Mobility. Doctoral thesis, UCL (University College London).
http://ift.tt/2gtVV52
Could ethanol-induced alterations in the expression of glutamate transporters in testes contribute to the effect of paternal drinking on the risk of abnormalities in the offspring?
Publication date: Available online 24 November 2016
Source:Medical Hypotheses
Author(s): Mohammed Abul Kashem, Aven Lee, David V. Pow, Omar Šerý, Vladimir J. Balcar
It has been known that a preconception paternal alcoholism impacts adversely on the offspring but the mechanism of the effect is uncertain. Several findings suggest that there are signalling systems in testis that are analogous to those known to be altered by alcoholism in brain. We propose that chronic alcohol affects these systems in a manner similar to that in brain. Specifically, we hypothesise that excessive alcohol may disturb glutamatergic-like signalling in testis by increasing expression of the glutamate transporter GLAST (EAAT1). We discuss ways how to test the hypothesis as well as potential significance of some of the tests as tools in the diagnostics of chronic alcoholism.
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Paying the price for body evolution
Publication date: Available online 24 November 2016
Source:Medical Hypotheses
Author(s): Francesca G. Magnani, Anna Sedda
Since its beginning, research about cognitive representation of our bodies has debated over multiple representations models. Furthermore, recent years have seen a rise in the study of body representation disorders and related impairments. However, why human beings manifest so many deficits is still a mystery. Considering human evolution, frontal brain regions are well known for their changes in dimensions and connections. Less known is that parietal and temporal lobes encountered similar changes. These areas, especially in the right hemisphere, are crucial for body representation. Our hypothesis is that evolution of these areas determined a more varied and widespread cross wiring between the temporal and parietal lobes, increasing their communication pathways and their reciprocal influence. As such, these connections could lead to an increased probability of interconnected body and emotional disorders in humans. The prediction of this hypothesis is that all body representation disorders have an associated emotional component and vice versa. Evidence supporting the interconnection between emotional and body representation disorders derives from psychiatric diseases such as eating disorders. This hypothesis opens up new directions to understand body representation and points towards innovative solutions for the clinical treatments of body representation/emotional impairments.
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Heart rate variability regression and risk of sudden unexpected death in epilepsy
Publication date: Available online 25 November 2016
Source:Medical Hypotheses
Author(s): Alessio Galli, Federico Lombardi
The exact mechanisms of sudden unexpected death in epilepsy remain elusive, despite there is consensus that SUDEP is associated with severe derangements in the autonomic control to vital functions as breathing and heart rate regulation. Heart rate variability (HRV) has been advocated as biomarker of autonomic control to the heart. Cardiac dysautonomia has been found in diseases where other branches of the autonomous nervous system are damaged, as Parkinson disease and multiple system atrophy. In this perspective, an impaired HRV not only is a risk factor for sudden cardiac death mediated by arrhythmias, but also a potential biomarker for monitoring a progressive decline of the autonomous nervous system. This slope may lead to an acute imbalance of the regulatory pathways of vital functions after seizure and then to SUDEP.SUDEP: sudden unexpected death in epilepsy; HRV: heart rate variability.
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Hydrogen donors and acceptors and basic amino acids jointly contribute to carcinogenesis
Publication date: Available online 24 November 2016
Source:Medical Hypotheses
Author(s): Man Tang, Yanchao Zhou, Yiqi Li, Juntong Zou, Beicheng Yang, Li Cai, Xuelan Zhang, Qiuyun Liu
A hypothesis is postulated that high content of hydrogen donors and acceptors, and basic amino acids cause the intracellular trapping of the H+ and Cl- ions, which increases cancer risks as local formation of HCl is mutagenic to DNA. Other cations such as Ca2+, and weak acids such as short-chain organic acids may attenuate the intracellular gathering of the H+ and Cl-, two of the most abundant ions in the cells. Current data on increased cancer risks on diabetic and obese patients are consistent with the assumption that hydrogen bonding propensity on glucose, triglycerides and other molecules is among the causative factors.
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The gut-blood barrier permeability - a new marker in cardiovascular and metabolic diseases?
Publication date: Available online 24 November 2016
Source:Medical Hypotheses
Author(s): Marcin Ufnal, Kinga Pham
Recent studies suggest that blood-borne metabolites of gut microbiota, such as trimethylamine N-oxide (TMAO) are involved in the aetiology of cardiovascular diseases and may serve as markers of cardiovascular risk. To enter the bloodstream the microbiota-derived molecules need to pass the gut-blood barrier (GBB). The GBB plays an important role in maintaining organism homeostasis. It is a complex multi-layer system which determines the absorption of nutrients, water and many other substances. The integrity and permeability of the GBB may be impaired in numerous diseases including gastrointestinal, metabolic and cardiovascular diseases. Here, we propose that the evaluation of the GBB permeability may have a significant diagnostic potential in cardiovascular and metabolic diseases. Second, we suggest that the GBB permeability is a variable that confounds diagnostic value of new gut microbiota-derived biomarkers such as TMAO. Therefore, cardiovascular risk assessment requires the evaluation of both TMAO and the GBB permeability.
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The synthesis and biological evaluation of alkyl and benzyl naphthyridinium analogs of eupolauridine as potential antimicrobial and cytotoxic agents
Publication date: 1 December 2016
Source:Bioorganic & Medicinal Chemistry, Volume 24, Issue 23
Author(s): Shahriyar Taghavi-Moghadam, Cecil D. Kwong, John A. Secrist, Shabana I. Khan, Alice M. Clark
Eupolauridine, an indenonaphthyridine alkaloid, has been previously reported by us to exhibit antifungal activity. This study describes the synthesis of new alkyl and benzyl naphthyridinium/pyridinium analogs of eupolauridine as potential antifungal agents. A majority of the analogs exhibited antifungal activity against opportunistic pathogens such as Candida albicans and Cryptococcus neoformans. Several of them were also effective against bacteria (Staphylococcus aureus, MRS, Pseudomonas and Mycobacterium) and the malaria parasite (Plasmodium falciparum) to variable extents. A number of analogs were also cytotoxic to human cancer cell lines.
Graphical abstract
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Synthesis and antimalarial activity of N-benzylated (N-arylcarbamoyl)alkylphosphonic acid derivatives
Publication date: 1 December 2016
Source:Bioorganic & Medicinal Chemistry, Volume 24, Issue 23
Author(s): Christiana M. Adeyemi, Faridoon, Michelle Isaacs, Dumisani Mnkandhla, Heinrich C. Hoppe, Rui W.M. Krause, Perry T. Kaye
A series of novel and readily accessible N-benzylated (N-arylcarbamoyl)alkylphosphonate esters and related compounds have been prepared as potential antimalarial agents. Bioassays reveal that some of these compounds exhibit promising activity against Plasmodium falciparum, and exhibit no significant growth inhibition of HeLa cells.
Graphical abstract
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Design, synthesis, and biological activity of novel, potent, and highly selective fused pyrimidine-2-carboxamide-4-one-based matrix metalloproteinase (MMP)-13 zinc-binding inhibitors
Publication date: 1 December 2016
Source:Bioorganic & Medicinal Chemistry, Volume 24, Issue 23
Author(s): Hiroshi Nara, Kenjiro Sato, Akira Kaieda, Hideyuki Oki, Haruhiko Kuno, Takashi Santou, Naoyuki Kanzaki, Jun Terauchi, Osamu Uchikawa, Masakuni Kori
Matrix metalloproteinase-13 (MMP-13), a member of the collagenase family of enzymes, has been implicated to play a key role in the pathology of osteoarthritis. Recently, we have reported the discovery of a series of quinazoline-2-carboxamide based non-zinc-binding MMP-13 selective inhibitors, as exemplified by compound 1. We then continued our research of a novel class of zinc-binding inhibitors to obtain follow-up compounds with different physicochemical, pharmacokinetic, and biological activity profiles. In order to design selective MMP-13 inhibitors, we adopted a strategy of connecting a zinc-binding group with the quinazoline-2-carboxamide system, a unique S1′ binder, by an appropriate linker. Among synthesized compounds, a triazolone inhibitor 35 exhibited excellent potency (IC50=0.071nM) and selectivity (greater than 170-fold) over other MMPs (MMP-1, 2, 3, 7, 8, 9, 10, 12, and 14) and tumor necrosis factor-α converting enzyme (TACE). In this article, the design, synthesis, and biological activity of novel zinc-binding MMP-13 inhibitors are described.
Graphical abstract
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Synthesis, activity and docking studies of phenylpyrimidine–carboxamide Sorafenib derivatives
Publication date: 1 December 2016
Source:Bioorganic & Medicinal Chemistry, Volume 24, Issue 23
Author(s): Wenhui Wang, Chunjiang Wu, Jianqiang Wang, Rong Luo, Caolin Wang, Xiaobo Liu, Jiqing Li, Wufu Zhu, Pengwu Zheng
Two series of Sorafenib derivatives bearing phenylpyrimidine–carboxamide moiety (16a–g and 17a–p) were designed, synthesized and evaluated for the IC50 values against three cancer cell lines (A549, MCF-7 and PC-3). Two selected compounds (17f and 17n) were further evaluated for the activity against VEGFR2/KDR kinase. More than half of the synthesized compounds showed moderate to excellent activity against three cancer cell lines. Compound 17f showed equal activity to Sorafenib against MCF-7 cell line, with the IC50 values of 6.35±0.43μM. Meanwhile, compound 17n revealed more active than Sorafenib against A549 cell line, with the IC50 values of 3.39±0.37μM. Structure–activity relationships (SARs) and docking studies indicated that the second series (17a–p) showed more active than the first series (16a–g). What's more, the introduction of fluoro atom to the phenoxy part played no significant impact on activity. In addition, the presence of electron-donating on aryl group was benefit for the activity.
Graphical abstract
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Editorial board
Publication date: 1 December 2016
Source:Bioorganic & Medicinal Chemistry, Volume 24, Issue 23
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Non-iatrogenic mandibular pressure sores
Source:British Journal of Oral and Maxillofacial Surgery
Author(s): G. Vithlani, N. Somaia, K. Shakib
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Anaphylaxis in a health maintenance organization: International Classification of Diseases coding and epinephrine auto-injector prescribing
Source:Annals of Allergy, Asthma & Immunology
Author(s): Deena Pourang, Michael Batech, Javed Sheikh, Shefali Samant, Michael Kaplan
BackgroundAccurate estimates of the incidence of anaphylaxis are limited. Current International Classification of Diseases, Ninth Revision (ICD-9) codes complicate accurate diagnosis of anaphylaxis and assessment of appropriate epinephrine prescribing.ObjectiveTo quantify the incidence and demographic character of patients with anaphylaxis-related ICD-9 codes in a large health maintenance organization and analyze epinephrine prescribing and dispensing rates.MethodsAll patients included had at least 12 months of continuous membership over a 4-year period from January 1, 2008 to December 31, 2012 and were selected based on anaphylaxis-related ICD-9 codes (N = 159,172). This algorithm was extrapolated from a previous study that used expanded ICD-9 codes to identify more cases of anaphylaxis. Individual chart reviews found that many expanded ICD-9 codes represented unconfirmed cases of anaphylaxis and therefore were excluded, resulting in analysis of 52,405 patients.ResultsIncidence of anaphylaxis over 4 years was 2.07%, with female predominance (56.5%) over male predominance (43.5%). Epinephrine was prescribed in 16.2% of total cases. Highest rates of epinephrine prescription were for traditional ICD-9 codes 995.0 (other anaphylactic shock) and 995.60 to 995.69 (anaphylactic shock caused by food) at 49.3% and 58.6%, respectively. Of the cases in which an epinephrine auto-injector was prescribed, it was dispensed 95.9% of the time, independent of copayment amount.ConclusionLow epinephrine auto-injector prescribing rates in cases of anaphylaxis suggest the continued difficulty in the diagnosis of anaphylaxis and could result in suboptimal treatment of potential future episodes.
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Anaphylaxis in a health maintenance organization: International Classification of Diseases coding and epinephrine auto-injector prescribing
Source:Annals of Allergy, Asthma & Immunology
Author(s): Deena Pourang, Michael Batech, Javed Sheikh, Shefali Samant, Michael Kaplan
BackgroundAccurate estimates of the incidence of anaphylaxis are limited. Current International Classification of Diseases, Ninth Revision (ICD-9) codes complicate accurate diagnosis of anaphylaxis and assessment of appropriate epinephrine prescribing.ObjectiveTo quantify the incidence and demographic character of patients with anaphylaxis-related ICD-9 codes in a large health maintenance organization and analyze epinephrine prescribing and dispensing rates.MethodsAll patients included had at least 12 months of continuous membership over a 4-year period from January 1, 2008 to December 31, 2012 and were selected based on anaphylaxis-related ICD-9 codes (N = 159,172). This algorithm was extrapolated from a previous study that used expanded ICD-9 codes to identify more cases of anaphylaxis. Individual chart reviews found that many expanded ICD-9 codes represented unconfirmed cases of anaphylaxis and therefore were excluded, resulting in analysis of 52,405 patients.ResultsIncidence of anaphylaxis over 4 years was 2.07%, with female predominance (56.5%) over male predominance (43.5%). Epinephrine was prescribed in 16.2% of total cases. Highest rates of epinephrine prescription were for traditional ICD-9 codes 995.0 (other anaphylactic shock) and 995.60 to 995.69 (anaphylactic shock caused by food) at 49.3% and 58.6%, respectively. Of the cases in which an epinephrine auto-injector was prescribed, it was dispensed 95.9% of the time, independent of copayment amount.ConclusionLow epinephrine auto-injector prescribing rates in cases of anaphylaxis suggest the continued difficulty in the diagnosis of anaphylaxis and could result in suboptimal treatment of potential future episodes.
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A metal-free fluorescence turn-on molecular probe for detection of nucleoside triphosphates
Chem. Commun., 2016, Accepted Manuscript
DOI: 10.1039/C6CC08386B, Communication
DOI: 10.1039/C6CC08386B, Communication
Carsten Schmuck, Debabrata Maity, Martin Ehlers, Mao Li
We report a fluorescence probe 1, which contains a naphthalimide fluorophore with two symmetric peptidic arms equipped with a tailor-made anion-binding motif, the guanidiniocarbonyl pyrrole moiety, for the detection of...
The content of this RSS Feed (c) The Royal Society of Chemistry
We report a fluorescence probe 1, which contains a naphthalimide fluorophore with two symmetric peptidic arms equipped with a tailor-made anion-binding motif, the guanidiniocarbonyl pyrrole moiety, for the detection of...
The content of this RSS Feed (c) The Royal Society of Chemistry
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[3+2]-Annulation of Platinum-Bound Azomethine Ylides with Distal C=C bonds of N-Allenamides
Chem. Commun., 2016, Accepted Manuscript
DOI: 10.1039/C6CC07874E, Communication
DOI: 10.1039/C6CC07874E, Communication
Nitin T. Patil, Indradweep Chakrabarty, Suleman M Inamdar, Manjur Oyasim Akram, Amol B. Gade, Subhrashis Banerjee, Saibal Bera
A Pt-catalyzed, highly regioselective, reaction between N-allenamides and imino-alkynes leading to pyrrolo[1,2-a]indoles is described. This represents the first example of [3+2]-annulation of Pt-bound azomethine ylides with the distal C=C bond...
The content of this RSS Feed (c) The Royal Society of Chemistry
A Pt-catalyzed, highly regioselective, reaction between N-allenamides and imino-alkynes leading to pyrrolo[1,2-a]indoles is described. This represents the first example of [3+2]-annulation of Pt-bound azomethine ylides with the distal C=C bond...
The content of this RSS Feed (c) The Royal Society of Chemistry
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Infrared spectroscopy and spectroscopic imaging in forensic science
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02244H, Critical Review
DOI: 10.1039/C6AN02244H, Critical Review
Andrew Ewing, Sergei Kazarian
Infrared spectroscopy and spectroscopic imaging, are robust, label free and inherently non-destructive methods with a high chemical specificity and sensitivity that are frequently employed in forensic science research and practices....
The content of this RSS Feed (c) The Royal Society of Chemistry
Infrared spectroscopy and spectroscopic imaging, are robust, label free and inherently non-destructive methods with a high chemical specificity and sensitivity that are frequently employed in forensic science research and practices....
The content of this RSS Feed (c) The Royal Society of Chemistry
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Concurrent Chemoradiotherapy With or Without Adjuvant Chemotherapy for Locally Advanced Nasopharyngeal Carcinoma Patients at High Risk of Distant Metastasis
Condition: Local Advanced High Risk Nasopharyngeal Carcinoma
Interventions: Drug: IMRT combine with cisplatin concurrent chemotherapy; Drug: IMRT combine with cisplatin concurrent chemotherapy plus capecitabine adjuvant chemotherapy
Sponsor: Zhao Chong
Not yet recruiting - verified November 2016
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Interventions: Drug: IMRT combine with cisplatin concurrent chemotherapy; Drug: IMRT combine with cisplatin concurrent chemotherapy plus capecitabine adjuvant chemotherapy
Sponsor: Zhao Chong
Not yet recruiting - verified November 2016
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Early Detection of Esophageal Cancer
Conditions: Esophageal Neoplasms; Stomach Neoplasms; Endoscopy, Gastrointestinal; Digestive System Endoscopic Surgical Procedures; Cytology
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting - verified December 2015
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Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting - verified December 2015
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Concurrent Chemoradiotherapy With or Without Adjuvant Chemotherapy for Locally Advanced Nasopharyngeal Carcinoma Patients at High Risk of Distant Metastasis
Condition: Local Advanced High Risk Nasopharyngeal Carcinoma
Interventions: Drug: IMRT combine with cisplatin concurrent chemotherapy; Drug: IMRT combine with cisplatin concurrent chemotherapy plus capecitabine adjuvant chemotherapy
Sponsor: Zhao Chong
Not yet recruiting - verified November 2016
http://ift.tt/2gcdMNe
Interventions: Drug: IMRT combine with cisplatin concurrent chemotherapy; Drug: IMRT combine with cisplatin concurrent chemotherapy plus capecitabine adjuvant chemotherapy
Sponsor: Zhao Chong
Not yet recruiting - verified November 2016
http://ift.tt/2gcdMNe
Early Detection of Esophageal Cancer
Conditions: Esophageal Neoplasms; Stomach Neoplasms; Endoscopy, Gastrointestinal; Digestive System Endoscopic Surgical Procedures; Cytology
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting - verified December 2015
http://ift.tt/2fyAOjc
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting - verified December 2015
http://ift.tt/2fyAOjc
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