JOURNALS .....
Tailoring Individualized Evaluation of Pediatric Abdominal Pain Using Ecological Momentary Assessment (EMA): A Pilot Study Testing Feasibility and AcceptabilityObjective: The current study aimed to determine if it was feasible and acceptable to use ecological momentary assessment (EMA) to assess individual associations between biopsychosocial contributors to chronic abdominal pain with two objective sensors and a mobile application. Specifically, we aimed to determine if it was possible to identify...
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Combined Thoracoscopic Surgical Stapling and Endobronchial Valve Placement For Lung Volume Reduction With Incomplete Lobar Fissures: An Experimental Pilot Animal StudyBackground: In patients with severe emphysema and complete fissures, bronchoscopic lung volume reduction with valves reduces target lobe volume providing improvement in respiratory symptoms, lung function, quality of life, and exercise capacity. It is estimated that up to 88% of patients with emphysema have at least 1 incomplete interlobar...
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Diabetic tubulopathy: effect of toll-like receptor 2, toll-like receptor 4, and nuclear factor κb in elderly type 2 diabetes mellitus patientsSuzan N Abou-Raya, Montasser M Zeid, Mona W Ayad, Maher K Abdnaby, Mohamed H ArafaEgyptian Journal of Obesity, Diabetes and Endocrinology 2018 4(2):31-37Objective The aims of the current study were to investigate the role of toll-like receptor (TLR)2, TLR4, and nuclear factor κB (NF-κB) expression in the pathogenesis of diabetic nephropathy (DN) in elderly...
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Unsuccessful story of ABT-639 in neuropathic pain in different phases of clinical trialsJasmine Sharma, Nirmal Singh, Amteshwar Singh JaggiJournal of Pharmaceutical Negative Results 2019 10(1):1-5Neuropathic pain is a chronic pain state caused by injury of the nervous system, and there are various conditions associated with it such as diabetic neuropathy, postherpetic neuralgia, cancer pain, trigeminal neuralgia, cervical radiculopathy, and anticancer and anti-HIV-induced neuropathic pain. The pathophysiological...
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Are emotional states based in the brain? A critique of affective brainocentrism from a physiological perspectiveAbstractWe call affective brainocentrism the tendency to privilege the brain over other parts of the organism when defining or explaining emotions. We distinguish two versions of this tendency. According to brain-sufficient, emotional states are entirely realized by brain processes. According to brain-master, emotional states are realized by both brain and bodily processes, but the latter...
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Marinobacterium iners (Iizuka and Komagata 1964) comb. nov. arising from the Synonymy of Marinobacterium georgiense González et al. 1997 and Pseudomonas iners Iizuka and Komagata 1964 (Approved Lists 1980)AbstractAlthough there is documented evidence in the literature that Marinobacterium georgiense González et al. 1997 and Pseudomonas iners Iizuka and Komagata 1964 (Approved Lists 1980) should be treated as heterotypic synonyms, the nomenclatural consequences have not been implemented. Based on...
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Seizure Related to the Split Extended-Release Bupropion Tablets in a Young Female PatientNo abstract availableCytomegalovirus Pneumonia Causing Acute Respiratory Distress Syndrome After Brentuximab Vedotin TherapyNo abstract availableHypomagnesemia and Hypocalcemia Caused by Proton-Pump Inhibitors Long-Term TherapyNo abstract availableThe Efficacy of Hypnotherapy in the Treatment of Functional DyspepsiaBackground: Functional dyspepsia (FD) is one of the most frequent functional gastrointestinal disorders...
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Cancer immunotherapy for the immunosuppressed: Dissecting the conundrum of safety and efficacyJoud HajjarJournal of Immunotherapy and Precision Oncology 2019 2(3):53-54Immunotherapy use in patients with HIV and non-small-cell lung cancer: Current dataKatherine A Scilla, Alessandro Russo, Christian RolfoJournal of Immunotherapy and Precision Oncology 2019 2(3):55-58Safety of immune checkpoint blockade in patients with cancer and preexisting autoimmune diseases and/or chronic inflammatory disordersMohsin...
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External ophthalmic videography – Tools and techniquesSantosh G HonavarIndian Journal of Ophthalmology 2019 67(9):1389-1390Bilateral granulomatous uveitis in an elderly femaleJyoti Kattige, Vinaya Kumar Konana, Kalpana BabuIndian Journal of Ophthalmology 2019 67(9):1391-1391Simplified updates on the pathophysiology and recent developments in the treatment of amblyopia: A reviewSanthan K S Gopal, Jai Kelkar, Aditya Kelkar, Abhishek PanditIndian Journal of Ophthalmology 2019 67(9):1392-1399Amblyopia...
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Racial/Ethnic and HIV risk category disparities in PrEP discontinuation among patients in publicly-funded primary care clinicsObjective: Dissemination of pre-Exposure Prophylaxis (PrEP) is a priority for reducing new HIV infections, especially among vulnerable populations. However, there are limited data available on PrEP discontinuation following initiation, an important component of the PrEP cascade. Design: Patients receiving PrEP within the San Francisco Department of Public Health Primary Care...
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Activity Mapping of Children in Play Using Multivariate Analysis of Movement EventsPurpose i. To develop an automated measurement technique for the assessment of both the form and intensity of physical activity undertaken by children during play. ii. To profile the varying activity across a cohort of children using a multivariate analysis of their movement patterns. Methods Ankle-worn accelerometers were used to record 40-minutes of activity during a school recess, for 24 children over 5 consecutive...
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Current status of cell-free DNA in head and neck cancer managementAshish Singhal, Akhlak Hussain, Akash Agarwal, Bimlesh ThakurAnnals of Indian Academy of Otorhinolaryngology Head and Neck Surgery 2019 3(1):1-7Tissue biopsies are temporally and spatially limited and often provide a brief snapshot of a single region of a heterogeneous tumor. Carcinogenesis is a complex process in which heterogeneity plays an important role in the development and progression. Research efforts are going on focusing...
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Exoskeletons Improve Locomotion Economy by Reducing Active Muscle VolumeExoskeletons that improve locomotion economy are typically engineered to reduce users' limb-joint mechanical work or moments. Yet, limb-joint dynamics do not reflect muscle dynamics, which dictate whole-body metabolic energy expenditure. Here, we hypothesize that exoskeletons primarily reduce user metabolic energy expenditure across locomotion conditions by reducing active muscle volume. Corresponding Author: Owen N. Beck, Georgia...
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Leveraging Economies of Scale via Collaborative Interdisciplinary Global Health Tracks (CIGHTs): Lessons From Three ProgramsAs interest in global health education continues to increase, residency programs seeking to accommodate learners' expectations for global health learning opportunities often face challenges providing high-quality global health training. To address these challenges, some residency programs collaborate across medical specialties to create interdepartmental global health residency...
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HLA-DQ2 and -DQ8 genotype frequency in Syrian celiac disease children: HLA-DQ relative risks evaluation BMC Gastroenterology(Open Access)Celiac disease: from etiological factors to evolving diagnostic approachesJournal of Gastroenterology When foods contain both a gluten-free claim and an allergen advisory statement for wheat: should consumers be concerned?European Journal of Clinical NutritionGoing Against the Grains: Gluten-Free Diets in Patients Without Celiac Disease—Worthwhile or Not?Digestive...
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Alternative Complement Pathway Activation Provokes A Hypercoagulable State with Diminished FibrinolysisIntroduction: Several disease processes trigger prolonged activation of the alternative complement pathway. Crosslinks between complement activation and physiologic changes in platelets and neutrophils have been identified, but how this interplay alters the hemostatic potential in humans remains undefined. We hypothesize that activation of the alternative pathway triggers a hypercoagulable state....
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Factors Influencing Pediatric Cochlear Implant Outcomes: Carolina Sibling StudyObjective: To determine the correlation between speech perception performance between pediatric sibling pairs with severe to profound sensory hearing loss receiving cochlear implants, and in cases of discordance in performance, determine which variables negatively impacted performance. Study Design: Retrospective chart review. Setting: Tertiary academic referral center. Subjects: Eighty-nine pediatric subjects, 43 sibling...
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Hyperparathyroidism Due to Concurrent Parathyroid Carcinoma and Parathyroid AdenomaParathyroid carcinoma is uncommon, and its coexistence with parathyroid adenoma is extremely rare. A 28-year-old woman with hyperparathyroidism underwent dual-phase 99mTc-sestamibi SPECT/CT scan for presurgical evaluation. The images showed intense activity inside the left side thyroid and mild activity inside the right side of the thyroid. The histopathologic findings showed intrathyroidal parathyroid carcinoma on...
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Intraoperative-evoked Potential Monitoring: From Homemade to Automated SystemsNo abstract availableCortical Oscillations and Connectivity During Postoperative RecoveryBackground: The objective of this study was to test whether postoperative electroencephalographic (EEG) biomarkers, parietal alpha power and frontal-parietal connectivity, were associated with measures of clinical recovery in adult surgical patients. Methods: This is a secondary analysis of a prospective cohort study that analyzed intraoperative...
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Confirmation of damaging effect of MSH2 c.2634+1G>C mutation on splicing, its classification and implications for counselingPublication date: November 2019Source: Cancer Genetics, Volume 239Author(s): Jelena Rakobradović, Ana Krivokuća, Stevo Jovandić, Vesna Kesić, Mirjana Branković-MagićAbstractIntroductionLynch syndrome (LS) is predisposing mainly to colorectal and endometrial carcinomas, but also to urinary tract cancers. LS association with upper urinary tract carcinomas is known, but its...
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Nanofiber-Reinforced Decellularized Amniotic Membrane Improves Limbal Stem Cell Transplantation in a Rabbit Model of Corneal Epithelial DefectPublication date: Available online 19 August 2019Source: Acta BiomaterialiaAuthor(s): Zhengbing Zhou, Da Long, Chih-Chien Hsu, Huanhuan Liu, Long Chen, Benjamin Slavin, Hui Lin, Xiaowei Li, Juyu Tang, Samuel Yiu, Sami Tuffaha, Hai-Quan MaoAbstractHuman amniotic membrane (AM) offers unique advantages as a matrix to support the transplantation of limbal stem...
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Echocardiographic score for prediction of pulmonary hypertension at catheterization: the Daunia Heart Failure RegistryBackground Right heart catheterization (RHC) is recommended by guidelines for the diagnosis of pulmonary hypertension, the definition of hemodynamic impairment and responsiveness to drug therapy. However, RHC is an invasive test with associated risk of complications. Noninvasive echocardiographic tools, possibly predictive of pulmonary hypertension at RHC, could be therefore extremely...
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Binaural Optimization of Cochlear Implants: Discarding Frequency Content Without Sacrificing Head-Shadow BenefitObjectives: Single-sided deafness cochlear-implant (SSD-CI) listeners and bilateral cochlear-implant (BI-CI) listeners gain near-normal levels of head-shadow benefit but limited binaural benefits. One possible reason for these limited binaural benefits is that cochlear places of stimulation tend to be mismatched between the ears. SSD-CI and BI-CI patients might benefit from a binaural fitting...
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Prevention of transmission of Mycobacterium abscessus among patients with cystic fibrosisPurpose of review Pulmonary nontuberculous mycobacterial (NTM) infection is recognized as one of the most challenging infections to treat among cystic fibrosis patients. The source of NTM infection, modes of transmission, and exposure risks are poorly understood. Healthcare-associated transmission of Mycobacterium abscessus among cystic fibrosis patients has been suspected and is a growing concern for cystic...
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Urgent-start peritoneal dialysis: is it ready for prime time?Purpose of review This review aims to provide an up-to-date summary of the definition, current practice and evidence regarding the role of urgent-start peritoneal dialysis (USPD) in patients with end-stage kidney disease who present with unplanned dialysis requirement without functional access. Recent findings USPD can be broadly defined as peritoneal dialysis initiation within the first 2 weeks after catheter insertion. Published practice...
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Carotid artery stenting: an updatePurpose of review To present the latest evidence about carotid artery stenting (CAS) including indications, safety, efficacy, and available equipment. Recent findings The micromesh stent, a new stent design which offers excellent flexibility and embolic protection, has been associated with promising outcomes. Summary CAS has emerged as a minimally invasive treatment method for carotid artery stenosis with comparable outcomes with surgical management. The implementation...
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Total intravenous anaesthesia in ambulatory carePurpose of review The purpose of this article is to review the use of total intravenous anaesthesia (TIVA) in ambulatory care. Recent findings The number of ambulatory surgery cases is likely to increase in coming years. Recent meta-analyses suggest that TIVA offers decreased postoperative nausea and vomiting (PONV) and decreased pain scores in the postanaesthesia care unit (PACU) in day case/ambulatory surgery patients when compared with volatile anaesthesia....
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Quantabio Continues Newborn Screening Expansion as Tech Adopted by Wisconsin State ProgramPublished on Aug 21, 2019 Color to Use $4.6M NIH Grant to Build 'All of Us' Genetic Counseling ResourcePublished on Aug 21, 2019 OpGen Progresses on Pipeline of Highly Multiplexed Drug-Resistant Bacteria TestsPublished on Aug 20, 2019 Stanford Team Uses Imputation Approach to Uncover Thousands of New Microbiome ProteinsPublished on Aug 20, 2019Beyond Cas9: CRISPR Gene Editing with Alternative Nucleases In this...
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Cardiac MRI, Complete Free-breathing Adenosine Stress Cardiac MRI Using Compressed Sensing and Motion Correction: Comparison of Functional Parameters, Perfusion, and Late Enhancement with the Standard Breath-holding Examination Free-breathing stress cardiac MRI delivers diagnostic image quality. Christoph Treutlein, Marco Wiesmüller... Wolfgang WuestReview Safety Considerations of 7-T MRI in Clinical PracticeMichael N. Hoff, Alexander McKinney IV...Emanuel KanalState of the Art Breast MRI: State...
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Editorial: Beware of Studies Claiming that Social Factors are "Independently Associated" with Biological Complications of SurgeryNo abstract availableEditor's Spotlight/Take 5: Misconceptions and the Acceptance of Evidence-based Nonsurgical Interventions for Knee Osteoarthritis. A Qualitative StudyNo abstract availableMisconceptions and the Acceptance of Evidence-based Nonsurgical Interventions for Knee Osteoarthritis. A Qualitative StudyBackground In contrast to best practice guidelines for knee...
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Peer Reviewers: A Vital Part of the Publication ProcessNo abstract availableReviewer Thank YouNo abstract availableCall for Peer ReviewersNo abstract availableAre You Appropriately Coding and Billing Medicare Part B for Disposable Negative-Pressure Wound Therapy?No abstract availablePressure Injuries in the Pediatric Population: A National Pressure Ulcer Advisory Panel White PaperGENERAL PURPOSE To review what is known about pediatric pressure injuries (PIs) and the specific factors that make neonates...
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New promising targets to control neuropathic painNo abstract availableVirtual reality, music, and pain: developing the premise for an interdisciplinary approach to pain managementNo abstract availableQuantitative sensory testing and predicting outcomes for musculoskeletal pain, disability, and negative affect: a systematic review and meta-analysisHypersensitivity due to central pain mechanisms can influence recovery and lead to worse clinical outcomes, but the ability of quantitative sensory testing...
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The Deep Sedation Conundrum and Paediatric EndoscopyNo abstract availableGastrointestinal Polyposis in Pediatric PatientsGastrointestinal polyps are mucosal overgrowths that, if unchecked, can undergo malignant transformation. Although relatively uncommon in the pediatric age group, they can be the harbingers of multiorgan cancer risk and require close management and follow-up. Additionally, as many polyposis syndromes are inherited, appropriate genetic testing and management of relatives is vital...
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Eleven Thoughts from Reading This IssueNo abstract availableACSM News BriefsNo abstract availableSHAREABLE RESOURCE: Every Day Is Physical Activity DayNo abstract availableGuidelines for Physical Activity and Health in the United States: Evolution over 50 YearsNo abstract availablePhysical Activity and DepressionNo abstract availableFeatured ArticlesNo abstract availableHOUSTON, WE HAVE A (PHYSICAL ACTIVITY) PROBLEMApply It! • Physical activity is associated with several health and well-being benefits,...
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Willingness to Participate in Atopic Dermatitis Research Studies and Clinical TrialsNo abstract availableAllergens in Medical Hand Skin Cleansers: Product Review and AlternativesHealth care workers may be at risk of occupational allergic contact dermatitis because of their frequent exposure to medical hand skin cleansers. We identified American Contact Dermatitis Society Core 80 Allergens (Dermatitis 2017;28(2):141–143) found in medical hand skin cleansers (waterless skin soaps, water-needed skin...
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Radiomics Toolkit: Available Chest Computed Tomography Data SetsNo abstract availableUsing Quantitative Computed Tomographic Imaging to Understand Chronic Obstructive Pulmonary Disease and Fibrotic Interstitial Lung Disease: State of the Art and Future DirectionsComputed tomography (CT) is commonly used in the evaluation and management of patients with diffuse lung pathologies, including chronic obstructive pulmonary disease (COPD) and fibrotic interstitial lung disease (ILD). In clinical practice,...
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Carcinoma ex pleomorphic adenoma: A review of incidence, demographics, risk factors, and survival☆☆☆☆☆☆Figures (3)Author links open overlay panelAvigeetGuptaSinaKoochakzadehDavid M.NeskeyShaun A.NguyenEric J.LentschDepartment of Otolaryngology – Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USAReceived 17 July 2019, Available online 21 August 2019.Show lesshttps://doi.org/10.1016/j.amjoto.2019.102279Get rights and contentAbstractPurposeIdentify variables that are independent...
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Aerodigestive Programs Enhance Outcomes in Pediatric PatientsThe early efforts of pediatric airway surgeons, gastroenterologists, and pulmonologists to optimize surgical outcomes involved evaluating multiple organ systems for diseases negatively affecting surgery. This resulted in coordinated clinics with multiple services, ancillary testing, and endoscopic procedures, known as aerodigestive programs. These programs have nationally increased the value of care, with multidisciplinary experts delivering...
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Critical Care Medicine,Recombinant Thrombomodulin on Neutrophil Extracellular Traps in Murine Intestinal Ischemia–ReperfusionNaoki Hayase, M.D.; Kent Doi, M.D.; Takahiro Hiruma, M.D.; Ryo Matsuura, M.D.; Yoshifumi Hamasaki, M.D.; Eisei Noiri, M.D.; Masaomi Nangaku, M.D.; Naoto Morimura, M.D.Anesthesiology Published online August 21, 2019. doi:10.1097/ALN.0000000000002898SPECIAL ANNOUNCEMENTJournal-related Activities and Other Special Activities at the 2019 American Society of Anesthesiologists MeetingMichael...
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JAMA CLINICAL CHALLENGE,Rapidly Progressive Vision Loss in a Patient With Breast Cancer,Michael C. Izzo, MD; Guri Bronner, MD; Carol L. Shields, MDEarn CME creditTRENDING NOW ON JAMA NETWORK OPENPush-up Exercise Capacity and Future Cardiovascular Events in Active Adult MenElectronic Health Record Design and Use Factors and Clinician Stress and BurnoutPatient Use of New Approach to Access Health Record Data Among 12 US Health SystemsPediatric Cannabis Exposure Before and After Medical Marijuana Legalization...
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Fragile Females: Case Series of Epilepsy in Girls With FMR1 DisruptionKenneth A. Myers, Femke N.G. van 't Hof, Lynette G. Sadleir, Geneviève Legault, Elisabeth Simard-Tremblay, David J. Amor and Ingrid E. SchefferPediatrics PerspectiveFlipping the Script on Emergency Care for Children With Medical ComplexityChristian D. Pulcini and David M. Rubin
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American Journal of NeuroradiologyPublication Preview articles for 22 August 2019ADULT BRAINComparison of Unenhanced and Gadolinium-Enhanced Imaging in Multiple Sclerosis: Is Contrast Needed for Routine Follow-Up MRI?G. Sadigh, A.M. Saindane, A.D. Waldman, N.S. Lava and R. HuAJNR Am J Neuroradiol first published on 22 August 2019 doi:10.3174/ajnr.A6179http://www.ajnr.org/content/early/2019/08/22/ajnr.A6179.abstractLETTERS (Online Only)An Important Pitfall in Diagnosing Intracanalicular Vestibular...
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The Adolescent Vaping Epidemic in the United States—How It Happened and Where We Go From HereZainab Farzal, MD, MPH; Martha F. Perry, MD; Wendell G. Yarbrough, MD, MMHC; et al.ORIGINAL INVESTIGATIONAnatomic Distribution of the Morphologic Variation of the Upper Lip Frenulum Among Healthy NewbornsShagnik Ray, BA; William Christopher Golden, MD; Jonathan Walsh, MDCLINICAL CHALLENGEEndoscopyMucocutaneous Lesions in an Adult Man Who Recently Moved From MexicoChristopher Mularczyk, MD; Matthew Moynihan,...
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Updates in Pediatric Otolaryngology Samantha Anne, Julina Ongkasuwan Copyright Contributors Contents Forthcoming Issues Erratum Not Just Smaller Ears, Noses, Throats, and Necks Sujana S. Chandrasekhar Updates in Pediatric Otolaryngology Samantha Anne, Julina Ongkasuwan What's New with Tubes, Tonsils, and Adenoids? Cinzia L. Marchica, John P. Dahl, Nikhila Raol Ankyloglossia and Other Oral Ties Jonathan Walsh, Margo McKenna Benoit Updates in Pediatric Cholesteatoma: Minimizing...
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Un decoder cerebrale per dialogare usando i pensieri,da MIND: Un nuovo sistema di decodifica dei segnali cerebrali non traduce più soltanto le intenzioni di parlare o i suoni uditi, come si è fatto finora, ma riproduce un dialogo nel suo insieme... - Leggi l'articolo → Difendere l'ambiente può uccidere più che andare in guerraTra il 2002 e il 2017 sono stati uccisi oltre 1500 attivisti impegnati nella difesa della natura. La corruzione e uno stato di diritto debole garantiscono spesso l'impunità... -...
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Cytotoxic action and proliferation in vitro and Analgesic Activity in vivo of Resin from Hymenaea stigonocarpa...Cytotoxic action and proliferation in vitro and Analgesic Activity in vivo of Resin from Hymenaea stigonocarpaKeyla Laisa Araújo E Saldanha, Vanessa de Andrade Royo, Francine Souza Alves Da Fonseca, Elytania Veiga Menezes, Dario Alves De Oliveira, Afrânio Farias De Melo, Kamylla Santos Teixeira, Murilo Malveira Brandão, Marcel Nani Leite, Guilherme Ferreira Caetano, Marco Andrey Cipriani...
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