Massive hemothorax resulting from a minor injury mechanism is considered to be rare particularly when the diaphragm is injured. We report a case of massive hemothorax with bleeding from the intercostal artery ...
https://ift.tt/2pG3jzB
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Σάββατο 6 Οκτωβρίου 2018
Massive hemothorax due to two bleeding sources with minor injury mechanism: a case report
Innate immunosensing of DNA in cellular senescence
Selene Glück | Andrea Ablasser
https://ift.tt/2OLT23i
SAMHD1 and the innate immune response to cytosolic DNA during DNA replication
Flavie Coquel | Christoph Neumayer | Yea-Lih Lin | Philippe Pasero
https://ift.tt/2PgZGvh
Control of autoreactive B cells by IgM and IgD B cell receptors: maintaining a fine balance
Mark Noviski | Julie Zikherman
https://ift.tt/2Pp7rz6
How neuraxial labor analgesia differs by approach: dural puncture epidural as a novel option
Abstract
Background and aim
Neuraxial analgesia techniques are not limited to just standard epidural and CSE blocks. A novel approach called dural puncture epidural (DPE) which is a modification of CSE in terms of practice has gained popularity after its description and use in the obstetric population. The aim of this review is to address the practice of DPE technique as a novel option by reviewing its benefits as well as side and/or adverse effects and to understand how neuraxial labor analgesia differs by approach based on the information available in the current literature
Discussion
Despite controversies and concerns, more rapid onset of analgesia, early bilateral sacral analgesia, lower incidence of asymmetric block and fewer maternal and fetal side effects are provided with DPE when compared to epidural.
Conclusion
DPE offers a favorable risk–benefit ratio for management of neuraxial analgesia as a novel option.
https://ift.tt/2BXteu5
The internal nasal valve: a validated grading system and operative guide
Abstract
Purpose
Nasal obstruction is a highly subjective and commonly reported symptom. The internal nasal valve (INV) is the rate limiting step to nasal airflow. A static INV grading score was devised with regard to visibility of the middle turbinate.
Methods
A prospective study of all patients who underwent primary external functional septorhinoplasty in 2017 for nasal obstruction. All patients' INV score was assessed pre- and postoperatively in a blinded and independent fashion by surgeons of varying seniority.
Results
Twenty-eight patients were studied, with mean age 30.9 years and follow-up 18.8 weeks. Inter-rater and test–retest reliability of INV grading were excellent, with Cronbach's alpha 0.936 and 0.920, respectively. There was also statistically significant improvement in both subjective and objective postoperative outcome measures including nasal inspiratory peak flows.
Conclusions
We demonstrate a novel, easy to interpret, clinically valuable grading system of the static internal nasal valve that is reliable and reproducible.
https://ift.tt/2BZJ2fQ
Role and Mechanism of the Nod-Like Receptor Family Pyrin Domain-Containing 3 Inflammasome in Oral Disease
Publication date: Available online 6 October 2018
Source: Archives of Oral Biology
Author(s): Kejia Lv, Guohua Wang, Chenlu Shen, Xia Zhang, Hua Yao
Abstract
Objective
To summarize evidence and data from experimental studies regarding the role and mechanism of the Nod-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome in the pathogenesis of several representative oral diseases.
Materials and methods
A literature search of PubMed and EBSCO was performed. The literature was searched using a combination of keywords, e.g., NLRP3 inflammasome, inflammation, microorganisms, oral inflammatory diseases, and oral immunological diseases.
Results
The initiation and activation of the NLRP3 inflammasome are associated with the pathogenesis and progression of several representative oral diseases, including periodontitis, oral lichen planus, dental pulp disease, and oral cavity squamous cell carcinoma.
Conclusions
The NLRP3 inflammasome plays a crucial role in the progression of inflammatory and adaptive immune responses. The possible role of the NLRP3 inflammasome in several oral diseases, including not only periodontitis and pulpitis but also mucosal diseases and oral cavity squamous cell carcinoma, may involve the aberrant regulation of inflammatory and immune responses. Understanding the cellular and molecular biology of the NLRP3 inflammasome is necessary because the NLRP3 inflammasome may be a potential therapeutic target for the treatment and prevention of oral inflammatory and immunological diseases.
https://ift.tt/2zUotzS
Interferon-induced epithelial response to rhinovirus-16 in asthma relates to inflammation and FEV1
Publication date: Available online 5 October 2018
Source: Journal of Allergy and Clinical Immunology
Author(s): Abilash Ravi, Jan Koster, Annemiek Dijkhuis, Suzanne M. Bal, Yanaika S. Sabogal Piñeros, Peter I. Bonta, Christof J. Majoor, Peter J. Sterk, René Lutter
https://ift.tt/2CvFHGw
Cholestenoic Acid is a Prognostic Biomarker in Acute Respiratory Distress Syndrome
Publication date: Available online 5 October 2018
Source: Journal of Allergy and Clinical Immunology
Author(s): Jennifer H. Madenspacher, Renee D. Stapleton, Benjamin T. Suratt, Anne E. Dixon, Fred B. Lih, Julie M. Lowe, Kara J. Mould, William J. Janssen, Eric D. Morrell, Mark M. Wurfel, Stavros Garantziotis, Kenneth B. Tomer, Michael B. Fessler
https://ift.tt/2IKzyGQ
Increased surface expression of NOTCH on memory T cells in peripheral blood from asthma patients
Publication date: Available online 5 October 2018
Source: Journal of Allergy and Clinical Immunology
Author(s): Irma Tindemans, Heleen Vroman, Melanie Lukkes, Menno van Nimwegen, Marjolein J.W. de Bruijn, Bobby W.S. Li, Alex Kleinjan, Geertje M. de Boer, Gerdien A. Tramper, Mirjam Kool, Gert-Jan Braunstahl, Rudi W. Hendriks
https://ift.tt/2Csb9oU
Human TBK1 is required for early autophagy induction upon HSV1 infection
Publication date: Available online 5 October 2018
Source: Journal of Allergy and Clinical Immunology
Author(s): Liyana Ahmad, Bayarchimeg Mashbat, Corwin Leung, Charlotte Brookes, Samar Hamad, Sina Krokowski, Avinash R. Shenoy, Lazaro Lorenzo, Michael Levin, Peter O'Hare, Shen-Ying Zhang, Jean-Laurent Casanova, Serge Mostowy, Vanessa Sancho-Shimizu
https://ift.tt/2E3jGAt
Carcinogenic epithelial-mesenchymal transition initiated by oral cancer exosomes is inhibited by anti-EGFR antibody cetuximab
Publication date: November 2018
Source: Oral Oncology, Volume 86
Author(s): Toshifumi Fujiwara, Takanori Eguchi, Chiharu Sogawa, Kisho Ono, Jun Murakami, Soichiro Ibaragi, Jun-ichi Asaumi, Stuart K. Calderwood, Kuniaki Okamoto, Ken-ichi Kozaki
Abstract
Overexpression and increased signaling from the epidermal growth factor receptor (EGFR) often changes oral squamous cell carcinoma (OSCC) and thus EGFR is frequently targeted molecularly by the therapeutic antibody cetuximab. We assessed the roles of OSCC-derived extracellular vesicles (EVs), including exosomes in the trafficking of cetuximab and in epithelial-mesenchymal transition (EMT) of epithelial cells. OSCC cells abundantly expressed EGFR, which was secreted from cells with OSCC-EVs upon EGF stimulations. The OSCC-EGFR-EVs were then able to enter into and transform epithelial cells leading to increased mesenchymal traits with increased vimentin and spindle-like shapes. EGF priming of OSCC cells further increased this EMT-initiating effect of the OSCC-EVs. The internalization and pro-EMT effects of the OSCC-EVs were largely blocked by cetuximab. Thus, OSCC-derived EVs transform normal epithelial cells into a mesenchymal phenotype and anti-EGFR therapeutic antibody cetuximab inhibits such a carcinogenic effect of the OSCC-EVs.
https://ift.tt/2RxEy5g
Small cell neuroendocrine carcinoma of the alveolar process of maxilla
Publication date: Available online 5 October 2018
Source: Oral Oncology
Author(s): Muhammad Shahid Iqbal, Sarah Matthews, Anne Chambers, Charles Kelly, Omar Ahmed, James Adams
https://ift.tt/2yj6DVs
Œdème palpébral induit par le pemetrexed (Alminta®)
Publication date: Available online 5 October 2018
Source: Annales de Dermatologie et de Vénéréologie
Author(s): A. Badaoui, E. Mahé
Résumé
Introduction
Les œdèmes palpébraux induits par les médicaments sont rares. Nous rapportons une observation de patient ayant développé ce type d'œdème sous chimiothérapie.
Observation
Un homme de 56 ans consultait pour un œdème bilatéral des paupières inférieures apparu 6 mois plus tôt, après trois cycles de pemetrexed-carboplatine prescrits pour un adénocarcinome bronchique avec métastases cérébrales. L'œdème, indolore et non prurigineux, était de consistance molle et s'aggravait progressivement. En l'absence d'autre cause, le diagnostic d'œdèmes dus au pemetrexed était retenu. Compte tenu de son efficacité, et avec l'accord du patient, ce traitement était néanmoins maintenu.
Discussion
Les œdèmes palpébraux secondaires aux injections de pemetrexed sont rares ; à ce jour, seuls 22 cas en ont été rapportés dans la littérature. Il convient donc d'éliminer tous les diagnostics différentiels avant de conclure à ce diagnostic. La physiopathologie est inconnue. Certains auteurs avancent une hypothèse identique aux œdèmes sous docetaxel : fuite capillaire protéique entraînant des œdèmes cutanés et sous-cutanés et des épanchements non tumoraux. D'autres traitements tels que des inhibiteurs de tyrosine kinase (imatinib et nilotinib) ou des inhibiteurs de mTOR (sirolimus) peuvent également induire des œdèmes palpébraux. Un cas d'excision chirurgicale des tissus palpébraux lymphœdémateux a été décrit, avec un bon résultat à 6 mois de suivi.
Summary
Background
Drug-induced eyelid edemas are rare. Herein, we describe a patient who developed this type of edema under chemotherapy.
Patients and methods
A 56-year-old male patient with a history of hypertension and adenocarcinoma of the lung with brain metastases consulted for incipient non-itchy eyelid edema with progressive worsening. The swelling occurred after 3 cycles of pemetrexed-carboplatin. There was no evidence of any other cause of edema. A diagnosis of pemetrexed-induced eyelid edema was made. Given the efficacy of this treatment and the patient's consent thereto, it was maintained.
Discussion
Palpebral edemas secondary to pemetrexed are very rare, with only 22 published cases in the literature. Other differential diagnoses must be ruled out before considering this etiology. The pathogenesis of eyelid edema remains unknown. One hypothesis is capillary protein leakage inducing swelling in soft tissue and non-malignant effusion, as has been suggested for docetaxel. Other agents such as tyrosine kinase inhibitors (imatinib and nilotinib) and mTOR inhibitors (sirolimus) may also cause eyelid edema. Treatment of eyelid edema is difficult and one case of surgical treatment has been published with good results and no recurrence after 6 months.
https://ift.tt/2IHu4fY
The relationship between autophagy, increased neutrophil extracellular traps formation and endothelial dysfunction in chronic kidney disease
Publication date: Available online 6 October 2018
Source: Clinical Immunology
Author(s): Jwa-Kyung Kim, Mi Jin Park, Hoi Woul Lee, Hyung Seok Lee, Sun Ryoung Choi, Young Rim Song, Hyung Jik Kim, Hyeong-Cheon Park, Sung Gyun Kim
Abstract
In chronic kidney disease (CKD), the number of circulating neutrophils are increased, and this is usually accompanied by an increased basal activation state. However, the possible association between neutrophil extracellular traps (NETs) with vascular complications has not been evaluated. We assessed the relationship between NETs, autophagy and endothelial dysfunction in maintenance hemodialysis (MHD) patients. NET formation, neutrophil elastase (NE) activities, and serum nucleosome levels were measured in MHD (n = 60) and controls (n = 20). Basal NET formation were markedly increased in MHD patient compared to controls. After PMA stimulation, MHD neutrophils showed significantly increased NETs formation response than controls. The degree of NETs was strongly associated with lower flow-mediated dilatation(%) of brachial artery even after adjustment for cardiovascular risk factors and uremic toxins. Moreover, MHD neutrophils showed increased basal autophagy activity. Interestingly, the levels of NETs were markedly augmented after autophagy inhibition, suggesting a protective role of autophagy in excessive NET formation.
https://ift.tt/2NrBioN
Podocyte foot process width is a prediction marker for complete renal response at 6 and 12 months after induction therapy in lupus nephritis
Publication date: Available online 5 October 2018
Source: Clinical Immunology
Author(s): Kunihiro Ichinose, Mineaki Kitamura, Shuntaro Sato, Keita Fujikawa, Yoshiro Horai, Naoki Matsuoka, Masahiko Tsuboi, Fumiaki Nonaka, Toshimasa Shimizu, Shoichi Fukui, Masataka Umeda, Tomohiro Koga, Shin-ya Kawashiri, Naoki Iwamoto, Takashi Igawa, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Tomoya Nishino, Atsushi Kawakami
Abstract
Morphological change that includes diffuse effacement of podocyte foot processes is correlated with proteinuria in patients with lupus nephritis (LN). We collected the data of clinico-pathological parameters and assessed foot process width (FPW) as an index of podocyte effacement in 73 patients with LN who had undergone renal biopsy. The multivariate analysis revealed that female gender (OR: 5.288; 95%CI: 1.197–37.29; p = .0267) and FPW (OR = 0.999, 95%CI = 0.997–0.999, p = .0150) were significantly predictive of a complete renal response (CR) at 6 months, while lymphocyte counts (OR = 1.002; 95%CI = 1.001–1.003, p = .0028) and FPW (OR = 0.998, 95%CI = 0.996–0.999, p = .0027) were significantly predictive of CR at 12 months. The cut-off point determined by the Classification and Regression Trees algorithm showed that FPW <908.3 nm provides the best performance for predicting patients who achieve CR at 12 months. A smaller FPW appears to be a predictive factor for CR at 6 and 12 months after induction therapy.
https://ift.tt/2y60I6O
Fra-2 is a novel candidate drug target expressed in the podocytes of lupus nephritis
Publication date: Available online 5 October 2018
Source: Clinical Immunology
Author(s): Changliang Xu, Yunjie Miao, Qingmeng Pi, Shoucao Zhu, Furong Li
Abstract
Lupus nephritis (LN) is a common and devastating complication caused by systemic lupus erythematosus. In this study, we evaluated the expression and mechanism of Fos-related antigen 2 (Fra-2) in LN. The results showed that Fra-2 was significantly increased in kidney biopsies of LN patients compared with healthy controls and other kidney disease in glomerular podocytes. The MRL/lpr mouse strain is a murine model of lupus, and it was used to study the mechanisms of Fra-2 in LN. The results showed that Fra-2 was expressed in the glomerular podocytes. We investigated the effects of inflammatory stimuli on Fra-2 protein expression in the glomerular podocytes, and found that interferon gamma was most effective at increasing Fra-2 protein expression. Knockdown of Fra-2 using siRNA enhanced the protein expression of nephrin. Therefore, Fra-2 may be a specific drug target for podocyte injury in LN.
https://ift.tt/2NrB9BL
Usefulness of serum biopterin as a predictive biomarker for childhood asthma control: A prospective cohort study
Publication date: Available online 5 October 2018
Source: Allergology International
Author(s): Saki Kasuga, Daijiro Kabata, Tomoko Sakaguchi, Satoshi Kudoh, Satsuki Nishigaki, Yusuke Higa, Shiori Fujikawa, Hiroko Fujitani, Ayumi Shintani, Takashi Hamazaki, Haruo Shintaku
Abstract
Background
Pteridines are metabolites of tetrahydrobiopterin, which serves as co-enzyme of nitric oxide synthase. We sought to investigate the usefulness of pteridines as biomarkers for childhood asthma control.
Methods
We conducted a single-center prospective cohort study involving 168 asthmatic children aged 4–17 years who visited the periodical asthma checkup program. Serum neopterin and biopterin levels were measured as pteridines at each visit along with measurement of FeNO, respiratory function tests, nasal eosinophil test, blood eosinophil count, and IgE level. We calculated coefficients for relation between pteridines and asthma control, which was assessed by questionnaires (JPAC: Japanese Pediatric Asthma Control Program).
Results
A total of 168 participants aged 10.3 ± 3.39 years (mean ± SD) with asthma were recruited. The participants in this study contained 58 patients (34.5%) of complete-controlled based on JPAC, 132 patients (76.0%) of well-controlled group based on GINA. FeNO and serum neopterin level did not correlate with following period's JPAC scores. In contrast, serum biopterin level significantly correlated with following period's JPAC total score (Coefficients 0.398; 95% CI 0.164 to 0.632; p value 0.001) and frequency of wheezing during exercise (Coefficients 0.272; 95% CI 0.217 to 0.328; p value < 0.001).
Conclusions
We found serum biopterin effected the following period's control status of asthmatic children, thus monitoring biopterin level will be a useful for management of asthma to adjust treatment.
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The prevalence of otitis media in 2–3 year old Cameroonian children estimated by tympanometry
Publication date: Available online 6 October 2018
Source: International Journal of Pediatric Otorhinolaryngology
Author(s): John Njuma Libwea, Marie Kobela, Paul Koki Ndombo, Ritva K. Syrjänen, Heini Huhtala, Ninying Fointama, Sinata Koulla-Shiro, Hanna Nohynek, J. Pekka Nuorti, Arto A. Palmu
Abstract
Background
Acute otitis media is a common illness in children under-five years of age and associated with major health care resources in high-income countries. However, there is paucity of data on its epidemiology and clinical presentation in low-income countries. We estimated the prevalence of otitis media and assessed risk factors among children in Cameroon.
Methods
A community-based cross-sectional prevalence study of otitis media (OM) was performed on randomly selected children aged 2–3 years in Yaoundé, Cameroon from March to June 2013. OM was assessed by clinical inspection for chronic suppurative otitis media (CSOM) and tympanometry for otitis media with effusion (OME). CSOM was defined as draining of the middle ear with duration of more than two weeks and OME was defined as a flat 'type B' tympanogram.
Results
Out of 529 children enrolled in the study, 433 (56% males) subjects with available tympanograms were evaluated. Altogether, 9.7% (42/433) of children met the case definition of CSOM, OME or its complications. This consisted of 3 (0.7%) children identified with unilateral CSOM; 7 (1.6%) children with bilateral OME; 31 (7.2%) with unilateral OME and 1 (0.2%) subject with unilateral dry tympanic membrane perforation.
Logistic regression analyses showed statistically significant association between OM and parental reporting of "current symptoms of upper respiratory tract infections", Prevalence Odds Ratio (POR) = 3.71; 95% CI = 1.69–8.14).
Conclusion
As many as two out of a hundred children between the ages of 2–3 years were affected by significant middle ear disease i.e. CSOM or bilateral OME. These data could be useful as a baseline for estimating the impact of pneumococcal conjugate vaccines (PCV13) introduced in July 2011 for infants in Cameroon.
https://ift.tt/2Pgz6Ck
Angiotensin II-mediated suppression of synaptic proteins in mouse hippocampal neuronal HT22 cell was inhibited by propofol: role of calcium signaling pathway
Abstract
Purpose
Angiotensin II (Ang II) has been shown to be involved in neurological disorders. Propofol demonstrated neuroprotective effects in neurons.
Methods
Mouse hippocampal HT22 cells were pre-treated with propofol, followed by Ang II treatment. The expression of synaptic proteins (synapsin I and PSD95) was examined. The effects of propofol on Ang II-induced NADPH oxidase expression and superoxide anion generation were examined. The effects of propofol on intracellular calcium concentration, the activation of calcium/calmodulin-dependent protein kinase II (CaMKII), and protein kinase C (PKC) were measured.
Results
Ang II reduced the expression of synapsin I and PSD95, which was attenuated by propofol. Ang II-induced effects were blocked by Ang II type 1 receptor (AT1 receptor) blocker. Ang II induced the expression of NADPH oxidase and caused superoxide anion accumulation, which were attenuated by propofol. In addition, propofol induced intracellular calcium concentration, and activated CaMKII as well as PKCβ. Importantly, the Ang II-mediated effects were diminished by α-tocopherol, and the propofol-mediated effects were alleviated by calcium chelator, CaMKII inhibitor, and PKCβ inhibitor.
Conclusion
Ang II, via AT1 receptor, induced oxidative stress and reduced the expression of synapsin I and PSD95 in HT22 cells. Propofol may increase synapsin I and PSD95 expression by inhibiting oxidative stress and stimulating calcium signaling pathway.
https://ift.tt/2Nohi6x
Hailey‐Hailey disease successfully treated with vitamin D oral supplementation
Dermatologic Therapy, Volume 0, Issue ja, -Not available-.
https://ift.tt/2NtBLHr
Nilotinib induction of melanogenesis via reactive oxygen species‐dependent JNK activation in B16F0 mouse melanoma cells
Experimental Dermatology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2pESu0H
Brimonidine displays anti‐inflammatory properties in the skin through the modulation of the vascular barrier function
Experimental Dermatology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2PgTJhI
Recent developments and highlights in biomarkers in allergic diseases and asthma
Allergy, Volume 0, Issue ja, -Not available-.
https://ift.tt/2zVlSFW
Long‐term efficacy of novel therapies in moderate‐to‐severe plaque psoriasis: a systematic review and network meta‐analysis of PASI response
Journal of the European Academy of Dermatology and Venereology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2y5049B
Position Statement – Linear Prurigo is a Subtype of Chronic Prurigo
Journal of the European Academy of Dermatology and Venereology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2NrTL4S
Insuline resistance, mTOR and Hidradenitis suppurativa
Journal of the European Academy of Dermatology and Venereology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2y501dV
Acute localised exanthematous pustulosis due to metronidazole
Journal of the European Academy of Dermatology and Venereology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2Ns3UhI
mTORC1 at the crossroad of metabolism and immunity in hidradenitis suppurativa
Journal of the European Academy of Dermatology and Venereology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2y6sksk
The value of dermoscopy in diagnosing eyebrow loss in patients alopecia areata and frontal fibrosing alopecia
Journal of the European Academy of Dermatology and Venereology, Volume 0, Issue ja, -Not available-.
https://ift.tt/2NreBkW
International neural monitoring study group guideline 2018 part I: Staging bilateral thyroid surgery with monitoring loss of signal
The Laryngoscope, EarlyView.
https://ift.tt/2pDTHFv
Kids Nowadays Hear Better Than We Did: Declining Prevalence of Hearing Loss in US Youth, 1966–2010
The Laryngoscope, EarlyView.
https://ift.tt/2zUQbwm
Impact of face proportions on face attractiveness
Journal of Cosmetic Dermatology, EarlyView.
https://ift.tt/2OcU5tx
Clinical evaluation of the lightening effect of cytidine on hyperpigmented skin
Journal of Cosmetic Dermatology, EarlyView.
https://ift.tt/2E2tMS6
Use of a novel 589‐nm solid‐state laser for treatment of facial erythema
Journal of Cosmetic Dermatology, EarlyView.
https://ift.tt/2OdyBMX
Serum amyloid A levels in the blood of patients with atopic dermatitis and cutaneous T‐cell lymphoma
The Journal of Dermatology, EarlyView.
https://ift.tt/2y4atm2
Prediction of therapeutic response before and during i.v. cyclophosphamide pulse therapy for interstitial lung disease in systemic sclerosis: A longitudinal observational study
The Journal of Dermatology, EarlyView.
https://ift.tt/2NrhQbL
Ventricular Arrhythmia Burden in Patients With Heart Failure and Cardiac Resynchronization Devices: The Importance of Renal Function
Babu, GG; Webber, M; Providencia, R; Kumar, S; Gopalamurugan, A; Rogers, DP; Daw, HL; ... Segal, OR; + view all Babu, GG; Webber, M; Providencia, R; Kumar, S; Gopalamurugan, A; Rogers, DP; Daw, HL; Ahsan, S; Khan, F; Chow, A; Lowe, M; Rowland, E; Lambiase, P; Segal, OR; - view fewer (2016) Ventricular Arrhythmia Burden in Patients With Heart Failure and Cardiac Resynchronization Devices: The Importance of Renal Function. Journal of Cardiovascular Electrophysiology , 27 (11) pp. 1328-1336. 10.1111/jce.13080 . Green open access
https://ift.tt/2y2Pu2S
The unfinished issue of ischaemic stroke and embolic events during catheter ablation of atrial fibrillation
Providencia, R; Albenque, J-P; Boveda, S; (2017) The unfinished issue of ischaemic stroke and embolic events during catheter ablation of atrial fibrillation. [Letter]. Europace , 19 (5) p. 881. 10.1093/europace/euw027 . Green open access
https://ift.tt/2Npm7wt
Biological therapies targeting arrhythmias: Are cells and genes the answer?
Falconer, D; Papageorgiou, N; Androulakis, E; Alfallouji, Y; Lim, WY; Providencia, R; Tousoulis, D; (2018) Biological therapies targeting arrhythmias: Are cells and genes the answer? [Review]. Expert Opinion on Biological Therapy , 18 (3) pp. 237-249. 10.1080/14712598.2018.1410130 .
https://ift.tt/2y2RMPk
Ventricular tachycardia ablation in structural heart disease: Impact of ablation strategy and non-inducibility as an end-point on long term outcome
Breitenstein, A; Sawhney, V; Providencia, R; Honarbakhsh, S; Ullah, W; Dhinoja, MB; Schilling, RJ; ... Hunter, RJ; + view all Breitenstein, A; Sawhney, V; Providencia, R; Honarbakhsh, S; Ullah, W; Dhinoja, MB; Schilling, RJ; Babu, GG; Chow, A; Lambiase, P; Rajappan, K; Kalla, M; Cassar, M; Hall, M; Temple, IP; Bartoletti, S; Panikker, S; Kontogeorgis, A; Wong, T; Hunter, RJ; - view fewer (2018) Ventricular tachycardia ablation in structural heart disease: Impact of ablation strategy and non-inducibility as an end-point on long term outcome. International Journal of Cardiology 10.1016/j.ijcard.2018.08.099 . (In press).
https://ift.tt/2NoQIdL
Resistance Exercise Training in McArdle Disease: Myth or Reality?
Pietrusz, A; Scalco, RS; Quinlivan, R; (2018) Resistance Exercise Training in McArdle Disease: Myth or Reality? Case Reports in Neurological Medicine , 2018 , Article 9658251. 10.1155/2018/9658251 . Green open access
https://ift.tt/2y4al62
Left/right asymmetric collective migration of parapineal cells is mediated by focal FGF signalling activity in leading cells
Roussigné, M; Wei, L; Tsingos, E; Kuchling, F; Alkobtawi, M; Tsalavouta, M; Wittbrodt, J; ... Wilson, SW; + view all Roussigné, M; Wei, L; Tsingos, E; Kuchling, F; Alkobtawi, M; Tsalavouta, M; Wittbrodt, J; Carl, M; Blader, P; Wilson, SW; - view fewer (2018) Left/right asymmetric collective migration of parapineal cells is mediated by focal FGF signalling activity in leading cells. Proceedings of the National Academy of Sciences of the United States of America 10.1073/pnas.1812016115 . (In press). Green open access
https://ift.tt/2NvT1Mc
Numerical modelling of wave interaction with an FPSO using a combination of OpenFOAM R and Lagrangian models.
Higuera, P; Buldakov, E; Stagonas, D; (2018) Numerical modelling of wave interaction with an FPSO using a combination of OpenFOAM R and Lagrangian models. In: Proceedings of the 28th International Ocean and Polar Engineering Conference (Offshore and Polar Engineering Conference) ). (pp. pp. 1486-1491). International Society of Offshore and Polar Engineers: Sapporo, Japan.
https://ift.tt/2y2Odcf
Does the offer of e-cigarettes benefit smoking cessation among unselected smokers?
Brown, J; Shahab, L; West, R; (2018) Does the offer of e-cigarettes benefit smoking cessation among unselected smokers? [Letter]. Addiction (In press).
https://ift.tt/2Nq2ioT
Emotional Over- and Undereating in Children: A Longitudinal Analysis of Child and Contextual Predictors
Bjørklund, O; Wichstrøm, L; Llewellyn, CH; Steinsbekk, S; (2018) Emotional Over- and Undereating in Children: A Longitudinal Analysis of Child and Contextual Predictors. Child Development 10.1111/cdev.13110 . (In press).
https://ift.tt/2y2QEvn
How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis: analysis of 10,500 patients (Sjögren Big Data Project)
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Using primary care-based paper and telephone interventions to increase uptake of bowel scope screening in Yorkshire: a protocol of a randomised controlled trial
McGregor, LM; Kerrison, RS; Green, T; Macleod, U; Hughes, M; Gibbins, M; Morris, S; ... von Wagner, C; + view all McGregor, LM; Kerrison, RS; Green, T; Macleod, U; Hughes, M; Gibbins, M; Morris, S; Rees, C; von Wagner, C; - view fewer (2018) Using primary care-based paper and telephone interventions to increase uptake of bowel scope screening in Yorkshire: a protocol of a randomised controlled trial. BMJ Open , 8 (7) , Article e024616. 10.1136/bmjopen-2018-024616 . Green open access
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MIMO Radar and Cellular Coexistence: A Power-Efficient Approach Enabled by Interference Exploitation
Liu, F; Masouros, C; Li, A; Ratnarajah, T; Zhou, J; (2018) MIMO Radar and Cellular Coexistence: A Power-Efficient Approach Enabled by Interference Exploitation. IEEE Transactions on Signal Processing , 66 (14) pp. 3681-3695. 10.1109/TSP.2018.2833813 . Green open access
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Majority Rule, Compromise and the Democratic Legitimacy of Referendums
Bellamy, R; (2018) Majority Rule, Compromise and the Democratic Legitimacy of Referendums. Swiss Political Science Review , 24 (3) pp. 312-319. 10.1111/spsr.12315 .
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Quantum Trajectories: Real or Surreal?
Hiley, BJ; Van Reeth, P; (2018) Quantum Trajectories: Real or Surreal? Entropy , 20 (5) , Article 353. 10.3390/e20050353 . Green open access
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It's all in the eye of the beholder: Personality and personality disorder as interpersonal phenomena
Fonagy, P; Campbell, C; Luyten, P; (2018) It's all in the eye of the beholder: Personality and personality disorder as interpersonal phenomena. [Editorial comment]. European Journal of Personality (In press).
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Exploring C-peptide loss in type 1 diabetes using growth curve analysis
Besser, REJ; Ludvigsson, J; Hindmarsh, PC; Cole, TJ; (2018) Exploring C-peptide loss in type 1 diabetes using growth curve analysis. PLoS ONE , 13 (7) , Article e0199635. 10.1371/journal.pone.0199635 . Green open access
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Invasive ants take and squander native seeds: implications for native plant communities
Devenish, A; Gomez, C; Bridle, J; Newton, R; Sumner, S; (2018) Invasive ants take and squander native seeds: implications for native plant communities. Biological Invasions 10.1007/s10530-018-1829-6 . (In press). Green open access
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Selective prebiotic conversion of pyrimidine and purine anhydronucleosides into Watson-Crick base-pairing arabino-furanosyl nucleosides in water
Powner, MW; Roberts, S; Stairs, S; Bucar, D; Szabla, R; Todd, Z; Šponer, J; Powner, MW; Roberts, S; Stairs, S; Bucar, D; Szabla, R; Todd, Z; Šponer, J; Sasselov, DD; - view fewer (2018) Selective prebiotic conversion of pyrimidine and purine anhydronucleosides into Watson-Crick base-pairing arabino-furanosyl nucleosides in water. Nature Communications , 9 , Article 4073. 10.1038/s41467-018-06374-z . Green open access
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Reminiscence therapy for dementia: an abridged Cochrane systematic review of the evidence from randomized controlled trials
O'Philbin, L; Woods, B; Farrell, EM; Spector, AE; Orrell, M; (2018) Reminiscence therapy for dementia: an abridged Cochrane systematic review of the evidence from randomized controlled trials. Expert Review of Neurotherapeutics , 18 (9) pp. 715-727. 10.1080/14737175.2018.1509709 .
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Assessing the Efficiency of Thermal Pressurization Using Natural Pseudotachylyte-Bearing Rocks
Brantut, N; Mitchell, TM; (2018) Assessing the Efficiency of Thermal Pressurization Using Natural Pseudotachylyte-Bearing Rocks. Geophysical Research Letters 10.1029/2018GL078649 . (In press). Green open access
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