Αρχειοθήκη ιστολογίου

Παρασκευή 7 Σεπτεμβρίου 2018

Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma

Human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) has an improved outcome and may allow for treatment de-escalation. High-risk HPV (HR-HPV) infection is associated with deregulat...

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Trigeminal neuralgia associated with ophthalmic surgery: a case series

Trigeminal neuralgia is a rare cause of postoperative pain after ophthalmic surgery and has only been described twice in the international literature: one case of pain after vitrectomy with a crystalline lens ...

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The impact of the number of harvested central lymph nodes on the lymph node ratio

The purpose of this study was to analyze the impact of lymph node harvest on the lymph node ratio (LNR).

https://ift.tt/2Qb2JGa

Vibrant Soundbridge implantation via a retrofacial approach in a patient with congenital aural atresia

A method of Vibrant Soundbridge (VSB) placement to the round window (RW) via the retrofacial approach with preoperative evaluation of the relationship between the facial nerve (FN) and RW by 3D-CT reconstruction was proposed for the treatment of congenital aural atresia (CAA) patient.

https://ift.tt/2CxL0px

88thAnnual Meeting of the American Thyroid Association October 3–7, 2018 Marriott Marquis, Washington, DC

Thyroid, Ahead of Print.


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Primary classic Hodgkin lymphoma of the ileum and Epstein-Barr virus mucocutaneous ulcer of the colon: two entities compared

Abstract

Primary classic Hodgkin lymphoma of the gastrointestinal tract represents a rare occurrence. A full patient's work-up is essential in order to exclude a secondary intestinal involvement. Histologically Epstein-Barr virus mucocutaneous ulcer closely resembles Hodgkin lymphoma. The differential diagnosis between these two entities is relevant, since both the therapeutic approach and the clinical behavior are different. Herein, we describe a case of primary classic Hodgkin lymphoma arising in the ileum and a case of Epstein-Barr virus mucocutaneous ulcer of the colon, focusing on the main clinicopathological differences.



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Role of muscle spindle feedback in regulating muscle activity strength during walking at different speed in mice

Mayer, WP; Murray, AJ; Brenner-Morton, S; Jessell, TM; Tourtellotte, WG; Akay, T; (2018) Role of muscle spindle feedback in regulating muscle activity strength during walking at different speed in mice. Journal of Neurophysiology 10.1152/jn.00250.2018 . (In press).

https://ift.tt/2MdBdEY

Loss of PINK1 or Parkin function results in a progressive loss of mitochondrial function

Taanman, J-W; Protasoni, M; (2017) Loss of PINK1 or Parkin function results in a progressive loss of mitochondrial function. In: Hayat, MA, (ed.) Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. (pp. 187-209). Academic Press

https://ift.tt/2Qe8mmO

Markers of cognitive function in individuals with metabolic disease: Morquio syndrome and tyrosinemia type III

Blundell, J; Frisson, S; Chakrapani, A; Kearney, S; Vijay, S; MacDonald, A; Gissen, P; ... Olson, A; + view all Blundell, J; Frisson, S; Chakrapani, A; Kearney, S; Vijay, S; MacDonald, A; Gissen, P; Hendriksz, C; Olson, A; - view fewer (2018) Markers of cognitive function in individuals with metabolic disease: Morquio syndrome and tyrosinemia type III. Cognitive Neuropsychology , 35 (3-4) pp. 120-147. 10.1080/02643294.2018.1443913 .

https://ift.tt/2M8vIY6

Electrosprayed microparticles for intestinal delivery of prednisolone

Shams, T; Illangakoon, UE; Parhizkar, M; Harker, AH; Edirisinghe, S; Orlu, M; Edirisinghe, M; (2018) Electrosprayed microparticles for intestinal delivery of prednisolone. Journal of the Royal Society Interface , 15 (145) , Article 20180491. 10.1098/rsif.2018.0491 . Green open access

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Spectrum of movement disorders and neurotransmitter abnormalities in paediatric POLG disease

Papandreou, A; Rahman, S; Fratter, C; Ng, J; Meyer, E; Carr, LJ; Champion, M; ... Kurian, MA; + view all Papandreou, A; Rahman, S; Fratter, C; Ng, J; Meyer, E; Carr, LJ; Champion, M; Clarke, A; Gissen, P; Hemingway, C; Hussain, N; Jayawant, S; King, MD; Lynch, BJ; Mewasingh, L; Patel, J; Prabhakar, P; Neergheen, V; Pope, S; Heales, SJR; Poulton, J; Kurian, MA; - view fewer (2018) Spectrum of movement disorders and neurotransmitter abnormalities in paediatric POLG disease. Journal of Inherited Metabolic Disease 10.1007/s10545-018-0227-7 . (In press). Green open access

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Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer

Baruteau, J; Perocheau, DP; Hanley, J; Lorvellec, M; Rocha-Ferreira, E; Karda, R; Ng, J; ... Waddington, SN; + view all Baruteau, J; Perocheau, DP; Hanley, J; Lorvellec, M; Rocha-Ferreira, E; Karda, R; Ng, J; Suff, N; Diaz, JA; Rahim, AA; Hughes, MP; Banushi, B; Prunty, H; Hristova, M; Ridout, DA; Virasami, A; Heales, S; Howe, SJ; Buckley, SMK; Mills, PB; Gissen, P; Waddington, SN; - view fewer (2018) Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer. Nature Communications , 9 (1) , Article 3505. 10.1038/s41467-018-05972-1 . Green open access

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On the utility of occupants’ behavioural diversity information for building performance simulation: An exploratory case study

Tahmasebi, F; Mahdavi, A; (2018) On the utility of occupants' behavioural diversity information for building performance simulation: An exploratory case study. Energy and Buildings , 176 pp. 380-389. 10.1016/j.enbuild.2018.07.042 .

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Chapter 10: Right to Information

Shepherd, EJ; (2017) Chapter 10: Right to Information. In: MacNeil, H and Eastwood, T, (eds.) Currents of archival thinking. ABC-CLIO: Santa Barbara, CA, USA. Green open access

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Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

King, R; Struebing, FL; Li, Y; Wang, J; Koch, AA; Cooke Bailey, JN; Gharahkhani, P; ... Geisert, EE; + view all King, R; Struebing, FL; Li, Y; Wang, J; Koch, AA; Cooke Bailey, JN; Gharahkhani, P; International Glaucoma Genetics Consortium, ; NEIGHBORHOOD Consortium, ; MacGregor, S; Allingham, RR; Hauser, MA; Wiggs, JL; Geisert, EE; - view fewer (2018) Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma. PLoS Genetics , 14 (1) , Article e1007145. 10.1371/journal.pgen.1007145 . Green open access

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The Nature of European Solidarity: How National Citizenship is Supplemented by and Constrains European Citizenship

Bellamy, RP; Lacey, J; (2017) The Nature of European Solidarity: How National Citizenship is Supplemented by and Constrains European Citizenship. In: de Quadros, F and Sidjanski, D, (eds.) The Future of Europe: The Reform of the Eurozone and the Deepening of Political Union. (pp. 517-522). AA FDL Editora: Lisbon, Portugal.

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High dimensional change point estimation via sparse projection

Wang, T; Samworth, RJ; (2018) High dimensional change point estimation via sparse projection. Journal of the Royal Statistical Society. Series B: Statistical Methodology , 80 (1) pp. 57-83. 10.1111/rssb.12243 . Green open access

https://ift.tt/2M90AYb

Statistical and computational trade-offs in estimation of sparse principal components

Wang, T; Berthet, Q; Samworth, RJ; (2016) Statistical and computational trade-offs in estimation of sparse principal components. Annals of Statistics , 44 (5) pp. 1896-1930. 10.1214/15-AOS1369 . Green open access

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Introduction: Rethinking the Animal-Human Relation

Inston, K; Bellin, S; Mussgnug, F; (2019) Introduction: Rethinking the Animal-Human Relation. Paragraph (In press).

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Average-case hardness of RIP certification

Wang, T; Berthet, Q; Plan, Y; (2016) Average-case hardness of RIP certification. In: Lee, D D and Sugiyama, M and Luxburg, U V and Guyon, I and Garnett, R, (eds.) Advances in Neural Information Processing Systems 29 (NIPS 2016). NIPS Proceedings: Barcelona, Spain. Green open access

https://ift.tt/2QaCD62

The Animal-Human Relation in Jean-Jacques Rousseau's Discourse on Inequality

Inston, K; (2019) The Animal-Human Relation in Jean-Jacques Rousseau's Discourse on Inequality. Paragraph (In press).

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Biology Education: The Value of Taking Student Concerns Seriously

Reiss, MJ; (2018) Biology Education: The Value of Taking Student Concerns Seriously. Education Sciences , 8 (130) 10.3390/educsci8030130 . Green open access

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«Parlando vommi / con ser Brunetto» (Inf. XV 100-101). Dante in dialogo con Brunetto Latini

Keen, C; (2019) «Parlando vommi / con ser Brunetto» (Inf. XV 100-101). Dante in dialogo con Brunetto Latini. Studi Danteschi , 83 (1) pp. 1-22. (In press).

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Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions

Bangash, MA; Alles, SRA; Santana-Varela, S; Millet, Q; Sikandar, S; de Clauser, L; Ter Heegde, F; ... Wood, JN; + view all Bangash, MA; Alles, SRA; Santana-Varela, S; Millet, Q; Sikandar, S; de Clauser, L; Ter Heegde, F; Habib, AM; Pereira, V; Sexton, JE; Emery, EC; Li, S; Luiz, AP; Erdos, J; Gossage, SJ; Zhao, J; Cox, JJ; Wood, JN; - view fewer (2018) Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions. Wellcome Open Research , 3 , Article 78. 10.12688/wellcomeopenres.14641.1 . Green open access

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Emotional capture by fearful expressions varies with psychopathic traits

Ahmed, SP; Hodsoll, S; Dalton, P; Sebastian, CL; (2018) Emotional capture by fearful expressions varies with psychopathic traits. Cognition and Emotion , 32 (1) pp. 207-214. 10.1080/02699931.2016.1278358 . Green open access

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Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Solid Tumors

Conditions:   Breast Cancer;   Lung Cancer;   Colorectal Cancer;   Prostate Cancer;   Bladder Cancer;   Uterine Cancer;   Kidney Cancer;   Renal Pelvis Cancer;   Pancreatic Cancer;   Liver Cancer;   Stomach Cancer;   Ovarian Cancer;   Esophageal Cancer
Intervention:   Other: Blood Sample Collection
Sponsor:   Exact Sciences Corporation
Recruiting

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Effect of Guided Imagery for Radiotherapy-Related Distress in Patients With Head and Neck Cancer

Condition:   Head and Neck Cancer
Interventions:   Behavioral: Guided Imagery;   Other: Treatment as Usual
Sponsor:   University of Colorado, Denver
Not yet recruiting

https://ift.tt/2Q9PHIV

Relevante Interaktionen von Analgetika und Koanalgetika mit onkologischen Systemtherapeutika – wann wird es gefährlich?

Zusammenfassung

Hintergrund

Schmerz ist ein gefürchtetes und zugleich auch das häufigste Symptom bei Krebspatienten. Gleichzeitig ist es aber etwas, für dessen Behandlung effektive und gut verträgliche Medikamente zur Verfügung stehen. Da behandlungsbedürftige Schmerzen in jeder Phase der Erkrankung auftreten können, werden Schmerztherapie und tumorgerichtete Systemtherapie häufig gleichzeitig durchgeführt. Während die Zahl der verfügbaren analgetisch wirksamen Substanzen seit Jahrzehnten stagniert (es wurden lediglich neue galenische Zubereitungen entwickelt), entwickelt sich der Markt der verfügbaren und oft hoch wirksamen Onkologika nahezu explosionsartig. Damit steigt auch die Wahrscheinlichkeit klinisch relevanter und u. U. sogar tödlicher „drug-drug-interactions". Ein Drittel aller ambulanten onkologischen Patienten soll ein Risiko für das Auftreten einer Interaktion haben. Eine Sonderstellung nimmt hierbei Methadon ein, für dessen Antitumorwirkung es bis dato keinen wissenschaftlichen Beweis gibt, wohl aber für sein hohes Risikoprofil.

Ziel

Ziel dieses Artikels ist die Sensibilisierung des Onkologen und Palliativmediziners für die Bedeutung von Interaktionen. Exemplarisch werden einzelne Interaktionen erläutert und bewertet. Keineswegs wird an dieser Stelle der Anspruch auf Vollständigkeit erhoben. Hierzu wird auf (frei verfügbare) Datenbanken verwiesen.

Material und Methoden

Dieser Beitrag wurde unter Bezug auf die wissenschaftlichen Fachinformationen der erwähnten Substanzen, klinische Erfahrungsberichte sowie unter Zuhilfenahme einschlägiger Interaktionsportale erstellt. Die Auswahl der Substanzen erfolgte auf der Basis langjähriger internistisch onkologischer Erfahrung und der S3-Leitlinie Schmerz des Leitlinienprogramms Onkologie der AWMF (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften e.V.)



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Erratum zu: Europäische PanCare-Studien zu Spätfolgen nach Krebs im Kindes- und Jugendalter

Erratum zu:

Der Onkologe 2018

https://ift.tt/2QbXCFC

Im vorletzten Abschnitt zur Überschrift „Projekte PanCareSurFup und PanCareLIFE" muss es korrekt heißen (Ergänzung in kursiv):

… Von den 25 datenbereitstellenden Einrichtungen wurden demografische, klinische (z. B. zur …



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Commentary: Dimensions of the maxillary sinus drainage system associated with pathology of the sinus

Publication date: Available online 6 September 2018

Source: Archives of Oral Biology

Author(s): Yongchun Gu



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Corneal Blood Staining after Complicated Cataract Surgery

Purpose: To report the case of a patient with corneal blood staining after a complicated cataract surgery. Observations: We report on a 68-year-old woman who developed corneal blood staining secondary to hyphema after cataract surgery, despite the fact that intraocular pressure was not increased for a prolonged time. The corneal staining spontaneously cleared from the periphery towards the center. It was fully resolved after 2.5 years of follow-up. Conclusions and Importance: In case of hyphema induced by cataract surgery, performance of early anterior chamber washout should be considered to prevent corneal blood staining and poor visual outcome.
Case Rep Ophthalmol 2018;9:421–424

https://ift.tt/2CtY4fG

The effect of administration media on palatability and ease of swallowing of multiparticulate formulations

Lopez, FL; Ernest, TB; Orlu, M; Tuleu, C; (2018) The effect of administration media on palatability and ease of swallowing of multiparticulate formulations. International Journal of Pharmacology 10.1016/j.ijpharm.2018.08.021 . (In press). Green open access

https://ift.tt/2MYIspz

Experimental SEFDM Pipelined Iterative Detection Architecture with Improved Throughput

Ozan, W; Haigh, PA; Tan, B; Darwazeh, I; (2018) Experimental SEFDM Pipelined Iterative Detection Architecture with Improved Throughput. In: Proceedings of the 2018 IEEE 87th Vehicular Technology Conference (VTC Spring). IEEE: Porto, Portugal. Green open access

https://ift.tt/2NSzBlp

Ancient History and Contemporary Political Theory: The Case of Liberty

Arena, V; (2018) Ancient History and Contemporary Political Theory: The Case of Liberty. Journal of History of European Ideas (In press).

https://ift.tt/2MWiaE3

Focus, Neg-concord, and Negative Postverbal Subjects

Samek-Lodovici, V; (2019) Focus, Neg-concord, and Negative Postverbal Subjects. Italian Journal of Linguistics (In press).

https://ift.tt/2NULLub

The effects of high versus low talker variability and individual aptitude on phonetic training of Mandarin lexical tones

Dong, H; Clayards, M; Brown, H; Wonnacott, E; (2018) The effects of high versus low talker variability and individual aptitude on phonetic training of Mandarin lexical tones. PeerJ Preprints , 6 , Article e27063v1. 10.7287/peerj.preprints.27063 . Green open access

https://ift.tt/2Nv4Zd2

Improving the patient discharge process: Implementing actions derived from a Soft Systems Methodology Study

Emes, MR; Smith, S; Ward, S; Smith, A; (2019) Improving the patient discharge process: Implementing actions derived from a Soft Systems Methodology Study. Health Systems (In press).

https://ift.tt/2M7tl7y

Statistical learning and spelling: Evidence from an incidental learning experiment with children

Samara, A; Singh, D; Wonnacott, EA; (2018) Statistical learning and spelling: Evidence from an incidental learning experiment with children. Cognition (In press).

https://ift.tt/2NoXjJb

Upconversion nanocrystal "armoured' silica fibres with superior photoluminescence for miRNA detection

Wang, G; Fu, Y; Ren, Z; Huang, J; Best, S; Li, X; Han, G; (2018) Upconversion nanocrystal "armoured' silica fibres with superior photoluminescence for miRNA detection. Chemical Communications , 54 (49) pp. 6324-6327. 10.1039/c8cc03480j .

https://ift.tt/2NWxrS3

Gold nanorod-assembled ZnGa2O4:Cr nanofibers for LED-amplified gene silencing in cancer cells

Qin, L; Yan, P; Xie, C; Huang, J; Ren, Z; Li, X; Best, S; ... Han, G; + view all Qin, L; Yan, P; Xie, C; Huang, J; Ren, Z; Li, X; Best, S; Cai, X; Han, G; - view fewer (2018) Gold nanorod-assembled ZnGa2O4:Cr nanofibers for LED-amplified gene silencing in cancer cells. Nanoscale , 10 (28) pp. 13432-13442. 10.1039/c8nr03802c .

https://ift.tt/2MUGh61

Principled Imputation Made Simple: Multiple Imputation Using Gaussian Copulas

Metternich, N; Hollenbach, FM; Bojinov, I; Minhas, S; Ward, MD; Volfovsky, A; (2018) Principled Imputation Made Simple: Multiple Imputation Using Gaussian Copulas. Sociological Methods and Research (In press).

https://ift.tt/2O0lXwU

Towards an edition of the fragments of the Roman Republican Antiquarians

Arena, V; Piras, G; (2018) Towards an edition of the fragments of the Roman Republican Antiquarians. Res Publica Litterarum: studies in the classical tradition (In press).

https://ift.tt/2MYvaJB

Black-Asian Counterintimacies: Reading Sui Sin Far in Jamaica

Yao, CX; (2018) Black-Asian Counterintimacies: Reading Sui Sin Far in Jamaica. J19: The Journal of Nineteenth-Century Americanists , 6 (1) pp. 197-204. 10.1353/jnc.2018.0015 .

https://ift.tt/2M7sHXG

CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts

Publication date: Available online 6 September 2018

Source: Allergology International

Author(s): Hideyuki Takeshima, Masafumi Horie, Yu Mikami, Kosuke Makita, Naoya Miyashita, Hirotaka Matsuzaki, Satoshi Noguchi, Hirokazu Urushiyama, Yoshihisa Hiraishi, Akihisa Mitani, Zea Borok, Takahide Nagase, Yasuhiro Yamauchi

Abstract
Background

Bronchial asthma is a chronic airway disease characterized by eosinophilic airway inflammation. Lung fibroblasts activated by IL-13 serve as important sources of chemokines, such as eotaxins, contributing to persistent eosinophilic inflammation. Src-homology 2-containing protein (CISH), belonging to the suppressor of cytokine signaling (SOCS) family, acts as a negative regulator of cytokine induction. The aim of this study was to elucidate the role of CISH in the production of eosinophil chemotactic chemokines in human lung fibroblasts.

Methods

Normal human lung fibroblasts were stimulated by IL-13, and global gene expression profile was assessed by cDNA microarray. Expression changes and downstream of IL-13 signaling were evaluated by quantitative RT-PCR, ELISA or western blotting. Loss- and gain-of-function analyses of CISH were performed by small interfering RNA and vector overexpression, respectively.

Results

Ingenuity pathway analysis revealed that IL-13 induced chemokine signaling, including the eotaxin family, while significantly suppressing IFN-α/β signaling. Among eight SOCS family members, CISH was most strongly induced by IL-13 via phosphorylation of signal transducer and activator of transcription 6 (STAT6). Loss- and gain-of-function studies demonstrated that CISH negatively regulated the expression of CCL26.

Conclusions

These findings suggest that CISH plays a key role in the eosinophilic inflammation associated with bronchial asthma by regulating IL-13-induced CCL26 production. Augmentation of CISH function could be a novel approach for treating eosinophilic inflammation in severe asthma.



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Nécroses digitales révélant une maladie des agglutinines froides : traitement par rituximab

Publication date: Available online 7 September 2018

Source: Annales de Dermatologie et de Vénéréologie

Author(s): T. Klejtman, B. Garel, P. Senet, L. Tribout, C. Bachmeyer, A. Barbaud, J.-B. Monfort

Résumé
Introduction

Les nécroses des doigts sont rares en comparaison de celles des membres inférieurs. Elles sont une urgence médico-chirurgicale. Un bilan étiologique approfondi est indispensable. La maladie des agglutinines froides est une cause rare de nécroses digitales, de diagnostic difficile et souvent non recherchée.

Observation

Nous rapportons le cas d'un homme de 57 ans qui présentait un phénomène de Raynaud de la main gauche d'apparition récente, compliqué secondairement de nécroses digitales survenues après exposition professionnelle au froid (conducteur d'un chariot de manutention). Le bilan étiologique permettait de poser le diagnostic de maladie des agglutinines froides idiopathique. Un traitement par rituximab et des soins locaux ont permis une cicatrisation complète.

Discussion

La maladie des agglutinines froides est une cause rare d'anémie hémolytique auto-immune. Les signes cliniques cutanés, paroxystiques, déclenchés par le froid, sont au premier plan. Il existe une forme idiopathique et une forme secondaire à une hémopathie lymphoïde chronique, une maladie auto-immune ou une infection ; un bilan étiologique est indispensable. Le traitement qui permet d'obtenir le meilleur taux de réponse, associé à une bonne tolérance, est à ce jour le rituximab en perfusions hebdomadaires pendant 1 mois.

Summary
Background

Digital necrosis is rarer than lower limb necrosis and constitutes a medical or surgical emergency. Etiological evaluation is required. Cold agglutinin disease is a cause of digital necrosis but diagnosis is difficult.

Patients and methods

Herein we report the case of a 57-year-old man presenting recent paroxysmal acrosyndrome of the left hand subsequently complicated by digital necrosis following occupational exposure to cold in his work as a forklift driver. After etiological evaluation, a diagnosis of primary cold agglutinin disease was made. Intravenous rituximab and topical treatment resulted in complete healing.

Discussion

Cold agglutinin disease is a rare type of auto-immune hemolytic anemia. Following exposure to cold, paroxysmal cutaneous signs are frequent. The disease may be either primary or secondary with B-cell lymphoproliferative disorder, auto-immune disease or infection. A thorough workup is required. To date, the treatment combining the best positive response rate and good safety is rituximab in weekly perfusions over a 1-month period.



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Efficacité spectaculaire de l’ivermectine topique dans un cas de granulome facial aseptique idiopathique

Publication date: Available online 6 September 2018

Source: Annales de Dermatologie et de Vénéréologie

Author(s): E. Blind, N. Ropars, G. Safa



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Shared Decision Making for the Allergist

In the age of personalized medicine, patients are playing a greater role in their treatment decisions. The internet has allowed patients to better educate themselves about their health and come prepared to office visits with questions and opinions. In a survey of 300 patients who attended an allergy clinic, 53% indicated they searched online for information on allergy before their consultation.1 In consideration of the informed patient and increasing patient empowerment in healthcare decisions, personalized medicine cannot be implemented without shared decision making (SDM) between patients and healthcare providers.

https://ift.tt/2CtfKb9

The therapeutic effects of lipoxin A4 during treadmill exercise on monosodium iodoacetate-induced osteoarthritis in rats

Publication date: November 2018

Source: Molecular Immunology, Volume 103

Author(s): Yue Yang, Yang Wang, Yawei Kong, Xiaoning Zhang, He Zhang, Yi Gang, Lunhao Bai

Abstract

Lipoxin A4 (LXA4), a kind of adipokines, is a potent stop signal of inflammation. Our preliminary study found that LXA4 of serum and intra-articular lavage fluid (IALF) was rapidly elevated in 2 h and rapidly reduced to normal level at 4 h after moderate-intensity treadmill exercise. The aim was to confirm the therapeutic effects of LXA4 during treadmill exercise on rat model of monosodium iodoacetate (MIA)-induced OA and the detailed mechanism of LXA4 on OA. One hundred and twenty-four male Sprague-Dawley rats were submitted to two different protocols. A single session of treadmill exercise: sixty-four rats were randomly divided into treadmill exercise of different intensities for 60 min only once (n = 4). Formal treadmill exercise: sixty rats were randomly divided into six groups (n = 10): control group (CG), knee OA group (OAG), OA with treadmill exercise of different intensities (OAL, OAM and OAH), and OAM + BOC-2 (an antagonist of LXA4 receptor). The rats were evaluated by ELISA, histology, immunohistochemistry and western blotting. Fibroblast-like synoviocytes (FLSs) were obtained from knee joint of rats. The effects of LXA4 on interleukin (IL)-1β induced FLSs were evaluated by western blotting and immunofluorescence. The results of ELISA, histological evaluation, western blotting and immunohistochemistry indicated that OAM had a better treatment which could be suppressed by BOC-2. Moreover, LXA4 could attenuate the expression of matrix metalloproteinase (MMP)-3 and MMP-13 and suppress the expression of nuclear factor-kappa B (NF-κB) p65 induced by IL-1β in FLSs. The therapeutic effects of LXA4 during treadmill exercise on MIA-induced OA via inhibiting NF-κB signaling pathway.



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Biological function of SPNS2: From zebrafish to human

Publication date: November 2018

Source: Molecular Immunology, Volume 103

Author(s): Xiao Zhu, Kun Ren, Yong-Zhi Zeng, Zhi Zheng, Guang-Hui Yi

Abstract

Sphingosine-1-phosphate (S1P), a bioactive metabolite of sphingolipid, has an important role in lymphocyte trafficking, immune responses, vascular and embryonic development, cancer, bone homeostasis, etc. S1P is produced intracellularly and then secreted into the circulation to engage in the above physiological or pathological processes by regulating the proliferation, differentiation and survival of target cells; however, the underlying mechanisms of S1P secretion and function remain poorly understood. Recently, Spinster 2 (SPNS2), a newly identified transporter of S1P, was shown to act as a mediator of intracellular S1P release and play an important role in the regulation of S1P. In this review, we focus on the primary biological characteristics and functions of SPNS2 and provide novel insights into the development of therapies for S1P-related disorders.



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Revealing the protective and pathogenic potential of MAIT cells

Publication date: November 2018

Source: Molecular Immunology, Volume 103

Author(s): Criselle D'Souza, Zhenjun Chen, Alexandra J. Corbett

Abstract

Mucosal-associated Invariant T (MAIT) cells represent a large proportion of T cells in human blood, and are also present throughout the body, being concentrated at mucosal sites. Their high level of conservation throughout mammalian evolution and recognition of conserved microbial antigens, derived from precursors of riboflavin (vitamin B2) biosynthesis, suggest an important role in protective immunity to pathogens. However, the picture that is emerging of MAIT cell immune function is increasingly complex, with numerous correlations of MAIT cell numbers with human diseases, and with recent studies demonstrating their pathogenic potential. The conditions that drive MAIT cell responses towards a protective versus pathogenic role are only beginning to be deciphered and, yet, must be understood for any attempt to harness MAIT cells therapeutically. In this review we summarise our current knowledge of immune protection and pathology driven by MAIT cells, models used to study their role in immunity and steps towards elucidating the immune signals driving these responses.

Graphical abstract

Graphical abstract for this article



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Pathophysiology and inhibition of IL-23 signaling in psoriatic arthritis: A molecular insight

Publication date: Available online 6 September 2018

Source: Clinical Immunology

Author(s): Cuong Thach Nguyen, Yehudi Bloch, Katarzyna Składanowska, Savvas N. Savvides, Iannis E. Adamopoulos

Abstract

Psoriatic arthritis (PsA) is a chronic inflammatory arthritis of unknown etiology, and currently the cellular and molecular interactions that dictate its pathogenesis remain elusive. A role of the interleukin-23 (IL-23)/IL-23R (IL-23 receptor) interaction in the development of psoriasis and PsA is well established. As IL-23 regulates the differentiation and activation of innate and adaptive immunity, it pertains to a very complex pathophysiology involving a plethora of effectors and transducers. In this review, we will discuss recent advances on the cellular and molecular pathophysiological mechanisms that regulate the initiation and progression of PsA as well as new therapeutic approaches for IL-23/IL-23R targeted therapeutics.



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Corrigendum to “The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck” [Oral Oncol. 81 (2018) 100–108]

Publication date: Available online 7 September 2018

Source: Oral Oncology

Author(s): Vassiliki Saloura, Theodore Vougiouklakis, Kyunghee Burkitt, Yusuke Nakamura, Gordon L. Hager, Carter van Waes



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Panorama Dermatologische Praxis



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Es brennt uns wieder auf den Nägeln



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Tinea faciei durch Nannizzia persicolor

Zusammenfassung

Wir berichten über eine Tinea faciei durch Nannizzia (N.) persicolor. Der 4‑jährige Junge hatte sich vermutlich an einem Meerschweinchen infiziert. Gesicherte Infektionen durch N. persicolor sind in Deutschland sehr selten. Möglicherweise wird dieser zoo- und geophile Dermatophyt aber aufgrund seiner Ähnlichkeit mit Trichophyton (T.) mentagrophytes auch nur selten erkannt. Die diagnostischen Merkmale von N. persicolor und seine Unterscheidung von T. mentagrophytes werden deshalb dargestellt. Insbesondere bei Kontakt zu Nagetieren sollte auch an N. persicolor gedacht werden.



https://ift.tt/2McJyJ2

Bullosis diabeticorum

Zusammenfassung

Wir berichten über 2 Patienten mit Diabetes mellitus, bei denen sich an den Fingern oder Zehen bis zu 2 cm durchmessende Blasen entwickelten, die nach Ausschluss der zu diskutierenden Differenzialdiagnosen als Bullosis diabeticorum (BD) eingeordnet werden konnten. Die BD ist eine seltene Blasenbildung, die bei Menschen mit Diabetes hauptsächlich palmoplantar beobachtet wird. Das klinische Bild ist gekennzeichnet durch bis zu 10 cm durchmessende, prallelastisch gefüllte Blasen mit klarem bis hämorrhagischem Inhalt. Die Abheilung erfolgt narbenlos, seltener unter Hinterlassung postinflammatorischer Pigmentierung oder zarter Narben. Histopathologisch finden sich sowohl intra- als auch subepidermale Spaltbildungen bei weitgehend fehlendem entzündlichen Infiltrat. Die Ätiopathogenese der BD ist nicht geklärt.



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Schmerzhafte rezidivierende Ulzerationen am Bein



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Type 1 Laryngeal Cleft and feeding and swallowing difficulties in infants and toddlers: A Review

Clinical Otolaryngology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2oM4lK3

“Over the Internet” sale of prescription‐level topical corticosteroids and dilemma of dermatologists

International Journal of Dermatology, EarlyView.


https://ift.tt/2wKURlG

Nodular fasciitis, a forgotten entity

International Journal of Dermatology, EarlyView.


https://ift.tt/2wSTbXq

Correlation of clinical and pathologic evaluation of scarring alopecia

International Journal of Dermatology, EarlyView.


https://ift.tt/2Niod5x

Pemphigus foliaceus induced by topical imiquimod treatment

International Journal of Dermatology, EarlyView.


https://ift.tt/2wPg4eo

Issue Information

International Journal of Dermatology, Volume 57, Issue 10, Page i-iii,1147-1148, October 2018.


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Teaching and Learning Tips 12: Peer observation of teaching

International Journal of Dermatology, Volume 57, Issue 10, Page 1233-1236, October 2018.


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Chronic granulomatous skin lesions leading to a diagnosis of TAP1 deficiency syndrome

Pediatric Dermatology, EarlyView.


https://ift.tt/2MSEkam

A unique case of pressure‐induced alopecia following EEG monitoring

Pediatric Dermatology, EarlyView.


https://ift.tt/2Np30GN

Management of a rare presentation of Kindler disease with digital constriction bands—Case report

Pediatric Dermatology, EarlyView.


https://ift.tt/2wOuYS9

Thyroid dermopathy and acropachy in pediatric patients

Pediatric Dermatology, EarlyView.


https://ift.tt/2NmMQhk

Neonatal urticaria: Could it be CAPS?

Pediatric Dermatology, EarlyView.


https://ift.tt/2M88Ibp

Temporal trends in prenatal risk factors for the development of infantile hemangiomas

Pediatric Dermatology, EarlyView.


https://ift.tt/2NpKnCD

Subcutaneous fat necrosis of the newborn and associated hypercalcemia: A systematic review of the literature

Pediatric Dermatology, EarlyView.


https://ift.tt/2M5q2Oo

Diffuse cutaneous mastocytosis: Case report and literature review

Pediatric Dermatology, EarlyView.


https://ift.tt/2NqsMup

Natural history and extracutaneous involvement of congenital morphea: Multicenter retrospective cohort study and literature review

Pediatric Dermatology, EarlyView.


https://ift.tt/2M7LXV8

Surgical treatment outcomes of infantile hemangioma in children: Does prior medical treatment matter

Pediatric Dermatology, EarlyView.


https://ift.tt/2NmcEKw

Cytomegalovirus ulcers following radiotherapy for a Marjolin ulcer in a renal transplant recipient

Australasian Journal of Dermatology, EarlyView.


https://ift.tt/2CuwMG9

Issue Information

Australasian Journal of Dermatology, Volume 59, Issue S2, Page 1-2, August 2018.


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WCCS18 World Congress on Cancers of the Skin 2018 Sydney International Convention Centre 15‐18 August 2018

Australasian Journal of Dermatology, Volume 59, Issue S2, Page 3-23, August 2018.


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Systemic treatments for alopecia areata: A systematic review

Australasian Journal of Dermatology, EarlyView.


https://ift.tt/2Cp3Pey

Itching in a trichophytin contact dermatitis mouse model and the antipruritic effect of antifungal agents

Clinical and Experimental Dermatology, EarlyView.


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The Impact of Tobacco Cigarette Smoking on Spinal Cord Stimulation Effectiveness in Chronic Spine–Related Pain Patients

Background and Objectives Despite the observation that select nicotine receptor agonists have analgesic effects, smokers report higher pain scores and more functional impairments than lifelong nonsmokers, attributable to exaggerated stress responses, receptor desensitization, and altered pharmacokinetics compounded by accelerated structural damage resulting from impaired bone healing, osteoporosis, and advancement of disk disease. We hypothesized that smoking diminishes the analgesic response to spinal cord stimulation (SCS) in patients with chronic spine–related pain conditions. Methods A retrospective cohort study was performed at Cleveland Clinic by collecting and assessing data of 213 patients who had been implanted with SCS for spine-pain indications. History of tobacco smoking was subcategorized into 3 categories: past (former smoker), present (current smoker), or those who had never previously smoked (lifelong nonsmokers), and a multivariable linear regression was run to measure the correlation, if any, between smoking status and numerical rating scale pain score. In addition, opioid consumption at baseline and 12-month follow-up, expressed in milligram oral morphine equivalents, was collected and compared. Results Adjusted for differences, at 1-year follow-up, current smokers (n = 62) reported numerical rating scale pain score of 7.0, which is 1.93 (P

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Sweet syndrome in association with enterobiasis

The Journal of Dermatology, EarlyView.


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Primary cicatricial alopecia in a single‐race Asian population: A 10‐year nationwide population‐based study in South Korea

The Journal of Dermatology, EarlyView.


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Addition of oral mini pulse dexamethasone to NBUVB phototherapy and topical steroids helps arrest disease activity in patients with vitiligo

British Journal of Dermatology, Volume 0, Issue ja, -Not available-.


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“GENIPSO”: a French prospective study assessing instantaneous prevalence, clinical features and impact on quality of life of genital psoriasis among patients consulting for psoriasis

British Journal of Dermatology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2MVEWMj

Local interventions for actinic keratosis in organ transplant recipients: A systematic review

British Journal of Dermatology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2wQYg2C

Benefit‐risk of tofacitinib in patients with moderate to severe chronic plaque psoriasis: Pooled analysis across 6 clinical trials

British Journal of Dermatology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2MVEVYL

A new clinical variant of acquired reactive perforating dermatosis‐like bullous pemphigoid

British Journal of Dermatology, Volume 0, Issue ja, -Not available-.


https://ift.tt/2wPZkUh

Exploring gender gap and school differential effects in mathematics in Chilean primary schools

Muñoz-Chereau, B; (2018) Exploring gender gap and school differential effects in mathematics in Chilean primary schools. School Effectiveness and School Improvement 10.1080/09243453.2018.1503604 . (In press).

https://ift.tt/2oNrw6E

Blocking tactile input to one finger using anaesthetic enhances touch perception and learning in other fingers

Dempsey-Jones, H; Themistocleu, AC; Carone, D; Ng, TWC; Harrar, V; Makin, TR; (2018) Blocking tactile input to one finger using anaesthetic enhances touch perception and learning in other fingers. Journal of Experimental Psychology: General (In press). Green open access

https://ift.tt/2wTW0b0

Between Scylla and Charybdis: Charting the Wicked Problem of Reusing Health Data for Clinical Research Informatics

Lea, NC; Nicholls, J; Fitzpatrick, NK; (2018) Between Scylla and Charybdis: Charting the Wicked Problem of Reusing Health Data for Clinical Research Informatics. Yearbook of Medical Informatics , 27 (1) pp. 170-176. 10.1055/s-0038-1641219 . Green open access

https://ift.tt/2wQvC2c

Aquele evento, esta memória: notas sobre a antropologia das diásporas africanas no Novo Mundo

Scott, D; Brittes W. Pires, R; Sauma, JF; (2017) Aquele evento, esta memória: notas sobre a antropologia das diásporas africanas no Novo Mundo. Ilha Revista de Antropologia , 19 (2) pp. 277-312. 10.5007/2175-8034.2017v19n2p277 . Green open access

https://ift.tt/2wRINPB

Scaling-up camera traps: monitoring the planet's biodiversity with networks of remote sensors

Steenweg, R; Hebblewhite, M; Kays, R; Ahumada, J; Fisher, JT; Burton, C; Townsend, SE; ... Rich, LN; + view all Steenweg, R; Hebblewhite, M; Kays, R; Ahumada, J; Fisher, JT; Burton, C; Townsend, SE; Carbone, C; Rowcliffe, JM; Whittington, J; Brodie, J; Royle, JA; Switalski, A; Clevenger, AP; Heim, N; Rich, LN; - view fewer (2016) Scaling-up camera traps: monitoring the planet's biodiversity with networks of remote sensors. Frontiers in Ecology and the Environment , 15 (1) pp. 26-34. 10.1002/fee.1448 . Green open access

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Robust estimation of snare prevalence within a tropical forest context using N-mixture models

O'Kelly, HJ; Rowcliffe, JM; Durant, SM; Milner-Gulland, EJ; (2017) Robust estimation of snare prevalence within a tropical forest context using N-mixture models. Biological Conservation , 217 pp. 75-82. 10.1016/j.biocon.2017.10.007 .

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The troubled journey of QoS: From ATM to content networking, edge-computing and distributed internet governance

Pavlou, G; Psaras, I; (2018) The troubled journey of QoS: From ATM to content networking, edge-computing and distributed internet governance. Computer Communications 10.1016/j.comcom.2018.07.006 .

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Satellite remote sensing of ecosystem functions: opportunities, challenges and way forward

Pettorelli, N; Schulte to Bühne, H; Tulloch, A; Dubois, G; Macinnis-Ng, C; Queirós, AM; Keith, DA; ... Nicholson, E; + view all Pettorelli, N; Schulte to Bühne, H; Tulloch, A; Dubois, G; Macinnis-Ng, C; Queirós, AM; Keith, DA; Wegmann, M; Schrodt, F; Stellmes, M; Sonnenschein, R; Geller, GN; Roy, S; Somers, B; Murray, N; Bland, L; Geijzendorffer, I; Kerr, JT; Broszeit, S; Leitão, PJ; Duncan, C; El Serafy, G; He, KS; Blanchard, JL; Lucas, R; Mairota, P; Webb, TJ; Nicholson, E; - view fewer (2017) Satellite remote sensing of ecosystem functions: opportunities, challenges and way forward. Remote Sensing in Ecology and Conservation , 4 (2) pp. 71-93. 10.1002/rse2.59 . Green open access

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Gaia Radial Velocity Spectrometer

Cropper, M; Katz, D; Sartoretti, P; Prusti, T; de Bruijne, JHJ; Chassat, F; Charvet, P; ... Damerdji, Y; + view all Cropper, M; Katz, D; Sartoretti, P; Prusti, T; de Bruijne, JHJ; Chassat, F; Charvet, P; Boyadjian, J; Perryman, M; Sarri, G; Gare, P; Erdmann, M; Munari, U; Zwitter, T; Wilkinson, M; Arenou, F; Vallenari, A; Gomez, A; Panuzzo, P; Seabroke, G; Allende Prieto, C; Benson, K; Marchal, O; Huckle, H; Smith, M; Dolding, C; Janssen, K; Viala, Y; Blomme, R; Baker, S; Boudreault, S; Crifo, F; Soubiran, C; Fremat, Y; Jasniewicz, G; Guerrier, A; Guy, LP; Turon, C; Jean-Antoine-Piccolo, A; Thevenin, F; David, M; Gosset, E; Damerdji, Y; - view fewer (2018) Gaia Radial Velocity Spectrometer. Astronomy & Astrophysics , 616 , Article A5. 10.1051/0004-6361/201832763 . Green open access

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Observational Hertzsprung-Russell diagrams

Babusiaux, C; van Leeuwen, F; Barstow, MA; Jordi, C; Vallenari, A; Bossini, D; Bressan, A; ... Gaia Collaboration, .; + view all Babusiaux, C; van Leeuwen, F; Barstow, MA; Jordi, C; Vallenari, A; Bossini, D; Bressan, A; Cantat-Gaudin, T; van Leeuwen, M; Brown, AGA; Prusti, T; de Bruijne, JHJ; Bailer-Jones, CAL; Biermann, M; Evans, DW; Eyer, L; Jansen, F; Klioner, SA; Lammers, U; Lindegren, L; Luri, X; Mignard, F; Panem, C; Pourbaix, D; Randich, S; Sartoretti, P; Siddiqui, HI; Soubiran, C; Walton, NA; Arenou, F; Bastian, U; Cropper, M; Drimmel, R; Katz, D; Lattanzi, MG; Bakker, J; Cacciari, C; Castaneda, J; Chaoul, L; Cheek, N; De Angeli, F; Fabricius, C; Guerra, R; Holl, B; Masana, E; Messineo, R; Mowlavi, N; Nienartowicz, K; Panuzzo, P; Portell, J; Riello, M; Seabroke, GM; Tanga, P; Thevenin, F; Gracia-Abril, G; Comoretto, G; Garcia-Reinaldos, M; Teyssier, D; Altmann, M; Andrae, R; Audard, M; Bellas-Velidis, I; Benson, K; Berthier, J; Blomme, R; Burgess, P; Busso, G; Carry, B; Cellino, A; Clementini, G; Clotet, M; Creevey, O; Davidson, M; De Ridder, J; Delchambre, L; Dell'Oro, A; Ducourant, C; Fernandez-Hernandez, J; Fouesneau, M; Fremat, Y; Galluccio, L; Garcia-Torres, M; Gonzalez-Nunez, J; Gonzalez-Vidal, JJ; Gosset, E; Guy, LP; Halbwachs, J-L; Hambly, NC; Harrison, DL; Hernandez, J; Hestroffer, D; Hodgkin, ST; Hutton, A; Jasniewicz, G; Jean-Antoine-Piccolo, A; Jordan, S; Korn, AJ; Krone-Martins, A; Lanzafame, AC; Lebzelter, T; Loeffler, W; Manteiga, M; Marrese, PM; Martin-Fleitas, JM; Moitinho, A; Mora, A; Muinonen, K; Osinde, J; Pancino, E; Pauwels, T; Petit, J-M; Recio-Blanco, A; Richards, PJ; Rimoldini, L; Robin, AC; Sarro, LM; Siopis, C; Smith, M; Sozzetti, A; Sueveges, M; Torra, J; van Reeven, W; Abbas, U; Abreu Aramburu, A; Accart, S; Aerts, C; Altavilla, G; Alvarez, MA; Alvarez, R; Alves, J; Anderson, RI; Andrei, AH; Anglada Varela, E; Antiche, E; Antoja, T; Arcay, B; Astraatmadja, TL; Bach, N; Baker, SG; Balaguer-Nunez, L; Balm, P; Barache, C; Barata, C; Barbato, D; Barblan, F; Barklem, PS; Barrado, D; Barros, M; Bartholome Munoz, S; Bassilana, J-L; Becciani, U; Bellazzini, M; Berihuete, A; Bertones, S; Bianchi, L; Bienayme, O; Blanco-Cuaresma, S; Boch, T; Boeche, C; Bombrun, A; Borrachero, R; Bouquillon, S; Bourda, G; Bragaglia, A; Bramante, L; Breddels, MA; Brouillet, N; Bruesemeister, T; Brugaletta, E; Bucciarelli, B; Burlacu, A; Busonero, D; Butkevich, AG; Buzzi, R; Caffau, E; Cancelliere, R; Cannizzaro, G; Carballo, R; Carlucci, T; Carrasco, JM; Casamiquela, L; Castellani, M; Castro-Ginard, A; Charlot, P; Chemin, L; Chiavassa, A; Cocozza, G; Costigan, G; Cowell, S; Crifo, F; Crosta, M; Crowley, C; Cuypers, J; Dafonte, C; Damerdji, Y; Dapergolas, A; David, P; David, M; de laverny, P; De Luise, F; De March, R; de Martino, D; de Souza, R; de Torres, A; Debosscher, J; del Pozo, E; Delbo, M; Delgado, A; Delgado, HE; Diakite, S; Diener, C; Distefano, E; Dolding, C; Drazinos, P; Duran, J; Edvardsson, B; Enke, H; Eriksson, K; Esquej, P; Bontemps, GE; Fabre, C; Fabrizio, M; Faigler, S; Falcao, AJ; Casas, MF; Federici, L; Fedorets, G; Fernique, P; Figueras, F; Filippi, F; Findeisen, K; Fonti, A; Fraile, E; Fraser, M; Frezouls, B; Gai, M; Galleti, S; Garabato, D; Garcia-Sedano, F; Garofalo, A; Garralda, N; Gavel, A; Gavras, P; Gerssen, J; Geyer, R; Giacobbe, P; Gilmore, G; Girona, S; Giuffrida, G; Glass, F; Gomes, M; Granvik, M; Gueguen, A; Guerrier, A; Guiraud, J; Gutierrez-Sanchez, R; Haigron, R; Hatzidimitriou, D; Hauser, M; Haywood, M; Heiter, U; Helmi, A; Heu, J; Hilger, T; Hobbs, D; Hofmann, W; Holland, G; Huckle, HE; Hypki, A; Icardi, V; Janssen, K; Jevardat de Fombelle, G; Jonker, PG; Juhasz, AL; Julbe, F; Karampelas, A; Kewley, A; Klar, J; Kochoska, A; Kohley, R; Kolenberg, K; Kontizas, M; Kontizas, E; Koposov, SE; Kordopatis, G; Kostrzewa-Rutkowska, Z; Koubsky, P; Lambert, S; Lanza, AF; Lasne, Y; Lavigne, J-B; Le Fustec, Y; Le Poncin-Lafitte, C; Lebreton, Y; Leccia, S; Leclerc, N; Lecoeur-Taibi, I; Lenhardt, H; Leroux, F; Liao, S; Licata, E; Lindstrom, HEP; Lister, TA; Livanou, E; Lobel, A; Lopez, M; Managau, S; Mann, RG; Mantelet, G; Marchal, O; Marchant, JM; Marconi, M; Marinoni, S; Marschalko, G; Marshall, DJ; Martino, M; Marton, G; Mary, N; Massari, D; Matijevic, G; Mazeh, T; McMillan, PJ; Messina, S; Michalik, D; Millar, NR; Molina, D; Molinaro, R; Molnar, L; Montegriffo, P; Mor, R; Morbidelli, R; Morel, T; Morris, D; Mulone, AF; Muraveva, T; Musella, I; Nelemans, G; Nicastro, L; Noval, L; O'Mullane, W; Ordenovic, C; Ordonez-Blanco, D; Osborne, P; Pagani, C; Pagano, I; Pailler, F; Palacin, H; Palaversa, L; Panahi, A; Pawlak, M; Piersimoni, AM; Pineau, F-X; Plachy, E; Plum, G; Poggio, E; Poujoulet, E; Prsa, A; Pulone, L; Racero, E; Ragaini, S; Rambaux, N; Ramos-Lerate, M; Regibo, S; Reyle, C; Riclet, F; Ripepi, V; Riva, A; Rivard, A; Rixon, G; Roegiers, T; Roelens, M; Romero-Gomez, M; Rowell, N; Royer, F; Ruiz-Dern, L; Sadowski, G; Sagrista Selles, T; Sahlmann, J; Salgado, J; Salguero, E; Sanna, N; Santana-Ros, T; Sarasso, M; Savietto, H; Schultheis, M; Sciacca, E; Segol, M; Segovia, JC; Segransan, D; Shih, I-C; Siltala, L; Silva, AF; Smart, RL; Smith, KW; Solano, E; Solitro, F; Sordo, R; Soria Nieto, S; Souchay, J; Spagna, A; Spoto, F; Stampa, U; Steele, IA; Steidelmueller, H; Stephenson, CA; Stoev, H; Suess, FF; Surdej, J; Szabados, L; Szegedi-Elek, E; Tapiador, D; Taris, F; Tauran, G; Taylor, MB; Teixeira, R; Terrett, D; Teyssandier, P; Thuillot, W; Titarenko, A; Clotet, FT; Turon, C; Ulla, A; Utrilla, E; Uzzi, S; Vaillant, M; Valentini, G; Valette, V; van Elteren, A; Van Hemelryck, E; Vaschetto, M; Vecchiato, A; Veljanoski, J; Viala, Y; Vicente, D; Vogt, S; von Essen, C; Voss, H; Votruba, V; Voutsinas, S; Walmsley, G; Weiler, M; Wertz, O; Wevers, T; Wyrzykowski, L; Yoldas, A; Zerjal, M; Ziaeepour, H; Zorec, J; Zschocke, S; Zucker, S; Zurbach, C; Zwitter, T; Gaia Collaboration, .; - view fewer (2018) Observational Hertzsprung-Russell diagrams. Astronomy & Astrophysics , 616 , Article A10. 10.1051/0004-6361/201832843 . Green open access

https://ift.tt/2NUzZ2W

Processing the spectroscopic data

Sartoretti, P; Katz, D; Cropper, M; Panuzzo, P; Seabroke, GM; Viala, Y; Benson, K; ... Zerjal, M; + view all Sartoretti, P; Katz, D; Cropper, M; Panuzzo, P; Seabroke, GM; Viala, Y; Benson, K; Blomme, R; Jasniewicz, G; Jean-Antoine, A; Huckle, H; Smith, M; Baker, S; Crifo, F; Damerdji, Y; David, M; Dolding, C; Fremat, Y; Gosset, E; Guerrier, A; Guy, LP; Haigron, R; Janssen, K; Marchal, O; Plum, G; Soubiran, C; Thevenin, F; Ajaj, M; Allende Prieto, C; Babusiaux, C; Boudreault, S; Chemin, L; Delle Luche, C; Fabre, C; Gueguen, A; Hambly, NC; Lasne, Y; Meynadier, F; Pailler, F; Panem, C; Riclet, F; Royer, F; Tauran, G; Zurbach, C; Zwitter, T; Arenou, F; Gomez, A; Lemaitre, V; Leclerc, N; Morel, T; Munari, U; Turon, C; Zerjal, M; - view fewer (2018) Processing the spectroscopic data. Astronomy & Astrophysics , 616 , Article A6. 10.1051/0004-6361/201832836 . Green open access

https://ift.tt/2wQW8sq

Quasar Accretion Disk Sizes from Continuum Reverberation Mapping from the Dark Energy Survey

Mudd, D; Martini, P; Zu, Y; Kochanek, C; Peterson, BM; Kessler, R; Davis, TM; ... DES Collaboration, .; + view all Mudd, D; Martini, P; Zu, Y; Kochanek, C; Peterson, BM; Kessler, R; Davis, TM; Hoormann, JK; King, A; Lidman, C; Sommer, NE; Tucker, BE; Asorey, J; Hinton, S; Glazebrook, K; Kuehn, K; Lewis, G; Macaulay, E; Moeller, A; O'Neill, C; Zhang, B; Abbott, TMC; Abdalla, FB; Allam, S; Banerji, M; Benoit-Levy, A; Bertin, E; Brooks, D; Rosell, AC; Carollo, D; Kind, MC; Carretero, J; Cunha, CE; D'Andrea, CB; da Costa, LN; Davis, C; Desai, S; Doel, P; Fosalba, P; Garcia-Bellido, J; Gaztanaga, E; Gerdes, DW; Gruen, D; Gruendl, RA; Gschwend, J; Gutierrez, G; Hartley, WG; Honscheid, K; James, DJ; Kuhlmann, S; Kuropatkin, N; Lima, M; Maia, MAG; Marshall, JL; McMahon, RG; Menanteau, F; Miquel, R; Plazas, AA; Romer, AK; Sanchez, E; Schindler, R; Schubnell, M; Smith, M; Smith, RC; Soares-Santos, M; Sobreira, F; Suchyta, E; Swanson, MEC; Tarle, G; Thomas, D; Tucker, DL; Walker, AR; DES Collaboration, .; - view fewer (2018) Quasar Accretion Disk Sizes from Continuum Reverberation Mapping from the Dark Energy Survey. The Astrophysical Journal , 862 (2) , Article 123. 10.3847/1538-4357/aac9bb . Green open access

https://ift.tt/2wSmeu6