Journal of Neurosurgery, Ahead of Print.
OBJECT Current recommendations stress the need for cognitive parameters to be integrated in the evaluation of outcomes for intracranial meningioma surgery. The aim of this prospective study was to examine neurocognitive function in meningioma patients pre- and postoperatively. METHODS Patients with skull base (anterior and middle fossa) and convexity (anterior and posterior) meningiomas (n = 54) underwent neuropsychological examination prior to and 1 year after surgery. A control group (n = 52) of healthy volunteers matched for age, sex, and education underwent the same examination. Assessments included executive, memory, and motor functions with standardized testing. Patients with convexity meningiomas were clinically assessed for parietal association cortex functions. RESULTS All patients performed significantly worse (p < 0.05) in most neurocognitive domains than controls. The skull base group showed more disturbances in memory than the convexity group (p < 0.05). The anterior convexity group showed more deficits in executive function than the posterior convexity group, which presented with parietal association cortex deficits. Verbal deficits were more pronounced in the left hemisphere than in the right hemisphere. Patients with a large tumor (> 4 cm) had more severe neurocognitive deficits than those with a small tumor (< 4 cm). Postoperatively, patients showed no deterioration in neurocognitive function. Instead, significant improvement (p < 0.05) was observed in some executive, motor, and parietal association cortex functions. CONCLUSIONS According to the authors' findings, intracranial meningiomas may cause neurocognitive deficits in patients. Surgery does not cause a deterioration in cognitive function; instead, it may lead to improvements in some functions. Permanent neuropsychological postoperative deficits should be interpreted as tumor-induced rather than due to surgery.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1lhFD0G
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2020
(289)
- ► Φεβρουαρίου (28)
-
►
2019
(9071)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3642)
- ► Ιανουαρίου (3200)
-
►
2018
(39872)
- ► Δεκεμβρίου (3318)
- ► Σεπτεμβρίου (3683)
- ► Φεβρουαρίου (2693)
- ► Ιανουαρίου (3198)
-
►
2017
(41099)
- ► Δεκεμβρίου (3127)
- ► Σεπτεμβρίου (2173)
-
►
2016
(13807)
- ► Δεκεμβρίου (700)
- ► Σεπτεμβρίου (600)
- ► Φεβρουαρίου (1350)
- ► Ιανουαρίου (1400)
-
▼
2015
(1500)
-
▼
Δεκεμβρίου
(1450)
-
▼
Δεκ 05
(46)
- Stroke prevention by direct revascularization for ...
- Growth hormone–secreting macroadenoma of the pitui...
- Metabolic approach for tumor delineation in glioma...
- Comparison of computer-assisted planning and manua...
- Effects of intracranial meningioma location, size,...
- Prospective, multidisciplinary recording of periop...
- Panventriculomegaly with a wide foramen of Magendi...
- Seizures in supratentorial meningioma: a systemati...
- Risk factors for worsened muscle strength after th...
- Phase-contrast magnetic resonance imaging reveals ...
- Tumors of the peripheral nervous system: analysis ...
- Hemodynamic and morphological characteristics of u...
- Editorial: Seizures with meningioma
- Letter to the Editor: Innovations in neurosurgery
- A biomechanical comparison of 3 different posterio...
- The unusual presentation of a vascular injury afte...
- Far caudally migrated extraforaminal lumbosacral d...
- Effects of fusion and conservative treatment on di...
- Editorial: Vascular injury during spinal procedures
- Therapiekonzepte der diffusen Peritonitis
- Peritonitis
- Long term results of postoperative Intensity-Modul...
- First evidence of the European wildcat ( Felis sil...
- Incidence of Ascaris suum -specific antibodies in ...
- A mucin-like peptide from Fasciola hepatica induce...
- Georgia Primary Care Providers’ Knowledge of Hered...
- Goodness and Desire
- Why do East Asian children perform so well in PISA...
- In the Long Cool Hour: "The Ethical Project" by Ph...
- Income Inequality, Intergenerational Mobility, and...
- Meaning, signification, and suggestion: Berkeley o...
- Microcarriers’ suspension and flow dynamics in orb...
- Political risk insurance and bilateral investment ...
- Centrifugal partition chromatography in a biorefin...
- Mapping pneumonia research: A systematic analysis ...
- Concurrent sexual partnerships among married Zimba...
- Studies of plug formation in microchannel liquid-l...
- A new small molecule inhibitor of soluble guanylat...
- Reconciling Magnetically Induced Vertigo and Nysta...
- The impact of threat of shock on the framing effec...
- Gastrointestinal stability of peptide drugs
- How beliefs about self-creation inflate value in t...
- Integrating Presentation Into Holistic Site Manage...
- An evaluation of the epidemiology of medication di...
- The evolution of chromatin folding in mammals: a r...
- Cutaneous Leishmaniasis - skin Barrier Properties ...
-
▼
Δεκ 05
(46)
-
▼
Δεκεμβρίου
(1450)
Ετικέτες
Σάββατο 5 Δεκεμβρίου 2015
Effects of intracranial meningioma location, size, and surgery on neurocognitive functions: a 3-year prospective study
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου