Journal of Neurosurgery, Ahead of Print.
OBJECT Craniopharyngiomas are associated with a high rate of recurrence. The surgical management of recurrent lesions has been among the most challenging neurosurgical procedures because of the craniopharyngioma's complex topographical relationship with surrounding structures. The aim of this study was to define the determinative role of the site of origin on the growth pattern and clinical features of recurrent craniopharyngiomas. METHODS The authors performed a retrospective analysis of 52 patients who had undergone uniform treatment by a single surgeon. For each patient, data concerning symptoms and signs, imaging features, hypothalamic-pituitary function, and recurrence-free survival rate were collected. RESULTS For children, delayed puberty was more frequent in the group with Type I (infradiaphragmatic) craniopharyngioma than in the group with Type TS (tuberoinfundibular and suprasellar extraventricular) lesions (p < 0.05). For adults, blindness was more frequent in the Type I group than in the Type TS group (p < 0.05). Nausea or vomiting, delayed puberty, and growth retardation were more frequent in children than in adults (p < 0.05). Overall clinical outcome was good in 48.07% of the patients and poor in 51.92%. Patients with Type TS recurrent tumors had significantly worse functional outcomes and hypothalamic function than patients with the Type I recurrent tumors but better pituitary function especially in children. CONCLUSIONS The origin of recurrent craniopharyngiomas significantly affected the symptoms, signs, functional outcomes, and hypothalamic-pituitary functions of patients undergoing repeated surgery. Differences in tumor growth patterns and site of origin should be considered when one is comparing outcomes and survival across treatment paradigms in patients with recurrent craniopharyngiomas.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1Q9Zrjj
via IFTTT
Αρχειοθήκη ιστολογίου
-
►
2020
(289)
- ► Φεβρουαρίου (28)
-
►
2019
(9071)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3642)
- ► Ιανουαρίου (3200)
-
►
2018
(39872)
- ► Δεκεμβρίου (3318)
- ► Σεπτεμβρίου (3683)
- ► Φεβρουαρίου (2693)
- ► Ιανουαρίου (3198)
-
►
2017
(41099)
- ► Δεκεμβρίου (3127)
- ► Σεπτεμβρίου (2173)
-
►
2016
(13807)
- ► Δεκεμβρίου (700)
- ► Σεπτεμβρίου (600)
- ► Φεβρουαρίου (1350)
- ► Ιανουαρίου (1400)
-
▼
2015
(1500)
-
▼
Δεκεμβρίου
(1450)
-
▼
Δεκ 12
(50)
- Surgical management of bisphosphonate-related oste...
- Results of a Multicenter, Randomized, Double-Maske...
- Pharmacotherapy for Pediatric Generalized Anxiety ...
- Extracellular Toxoplasma gondii tachyzoites metabo...
- CD1a+ and CD83+ Langerhans cells are reduced in lo...
- mTOR pathway protein immunoexpression as a prognos...
- Intrathecal fentanyl abolishes the exaggerated blo...
- Endothelin regulates intermittent hypoxia-induced ...
- Increasing taurine intake and taurine synthesis im...
- Microglia modulate brainstem serotonergic expressi...
- Factors associated with having less than 20 natura...
- The Effect on Sodium/Iodide Symporter and Pendrin ...
- Transient spurious intrathecal immunoglobulin synt...
- Validation of the Chinese version of the FOUR scor...
- IJMS, Vol. 16, Pages 29772-29786: Microtubule-Asso...
- MMP2 and MMP7 at the invasive front of gastric can...
- Carcinosarcoma of the larynx consisting of squamou...
- Head and neck cancers: a clinico-pathological prof...
- The use of intraoperative triggered electromyograp...
- Scoliosis may increase the risk of recurrence of l...
- The role of obesity in the biomechanics and radiol...
- The rise and fall of the craniocervical junction r...
- Preoperative retrolisthesis as a risk factor of po...
- Economic value of treating lumbar disc herniation ...
- Letter to the Editor: Alternative approach in Type...
- Prevalence and type of cervical deformities among ...
- App-assisted external ventricular drain insertion
- Effectiveness of 2-methoxyestradiol in alleviating...
- Neuropsychological outcomes of subtemporal selecti...
- The safety of Pipeline flow diversion in fusiform ...
- Sonographic findings associated with stenosis prog...
- Origin of craniopharyngiomas: implications for gro...
- Identifying preoperative language tracts and predi...
- Dynamic telescopic craniotomy: a cadaveric study o...
- Prospective comparison of sinonasal outcomes after...
- Application of contrast-enhanced T1-weighted MRI-b...
- Treatment of ruptured complex and large/giant rupt...
- A cadaveric microanatomical study of the fascicula...
- EP24.15 as a potential regulator of Kisspeptin wit...
- Research-focused isolation of human islets from do...
- Activation of medulla-projecting perifornical neur...
- Nodal promotes functional luteolysis via downregul...
- Post stroke hemi-dystonia in children: a neglected...
- Salting-out-assisted liquid–liquid extraction as a...
- Downscaling the in vitro test of fungal bioremedia...
- Cervical Cancer Prevention in Malaysia: Knowledge ...
- Local cryosurgery and imiquimod: A successful comb...
- Blistering disease associated with diffuse large B...
- Spontaneous remission of aleukemic cutaneous myelo...
- Kissing tumors of sebaceous carcinoma on the eyeli...
-
▼
Δεκ 12
(50)
-
▼
Δεκεμβρίου
(1450)
Ετικέτες
Σάββατο 12 Δεκεμβρίου 2015
Origin of craniopharyngiomas: implications for growth pattern, clinical characteristics, and outcomes of tumor recurrence
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου