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Δευτέρα 1 Φεβρουαρίου 2016

7-(Benzofuran-2-yl)-7-deazadeoxyguanosine as a fluorescence turn-ON probe for single-strand DNA binding protein

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Chem. Commun., 2016, Accepted Manuscript
DOI: 10.1039/C5CC09700B, Communication
Munefumi Tokugawa, Yoshiaki Masaki, Jan Christian Canggadibrata, Kazuhei Kaneko, Takashi Shiozawa, Takashi Kanamori, Morten Grotli, L. Marcus Wilhelmsson, Mitsuo Sekine, Kohji Seio
7-(Benzofuran-2-yl)-7-deazadeoxyguanosine (BFdG) was synthesized and incorporated into an oligodeoxynucleotide (ODN). The single-stranded ODN containing BFdG shows 91-fold fluorescence enhancement upon binding of single-strand DNA binding protein.
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