Early detection of oral cancers: current status and future prospects.

Early detection of oral cancers: current status and future prospects.

Curr Opin Otolaryngol Head Neck Surg. 2016 Apr;24(2):110-114

Authors: Iyer S, Thankappan K, Balasubramanian D

Abstract
PURPOSE OF REVIEW: This article reviews the current literature and summarizes the latest developments in screening and early detection of oral cancers and looks at the future possibilities.
RECENT FINDINGS: Oral cancer is the best model for screening and prevention. The screening for oral cancer can be population based, opportunistic, or targeted. A long-term 15-year follow-up data of a randomized controlled study from a developing country setting indicated a sustained reduction in oral cancer mortality in high-risk individuals. Visual oral examination remains the mainstay in the screening. Several adjunctive techniques have been described to aid in the clinical examination of these lesions. A Cochrane review revealed that there is no evidence to recommend these adjuncts in clinically visible lesions. Salivary biomarkers seem to be promising as a tool for screening in the future. A Targeted Evidence Update for the US Preventive Services Task Force found no evidence on screening either in the general or selected high-risk population for oral cancer in the United States or on benefit of any adjunctive device affecting the performance of the screening examination.
SUMMARY: Current evidence shows that community based screening has a value in reducing the oral cancer mortality in high-risk group of population. But this evidence may not be universally applicable.

PMID: 26963670 [PubMed - as supplied by publisher]

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