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Τετάρτη 30 Μαρτίου 2016

Stabilization of 11/9-Helical [small alpha]/[small beta]-Peptide Foldamers in Protic Solvents

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Chem. Commun., 2016, Accepted Manuscript
DOI: 10.1039/C6CC01189F, Communication
Mihye Lee, Jihyun Shim, Philjae Kang, Moon-Gun Choi, Soo Hyuk Choi
[small alpha]/[small beta]-Peptides with alternating [small alpha]-amino acid and cis-2-aminocyclohexanecarboxylic acid (cis-ACHC) residues adopts 11/9-helical conformations, of which folding propensity decreases as solvent polarity increases. We report a modifed cis-ACHC residue, cis-2-amino-cis-4-methylcyclohexanecarboxylic acid,...
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