Endoscopic Endonasal Surgery for Purely Intra-Third Ventricle Craniopharyngioma.

Endoscopic Endonasal Surgery for Purely Intra-Third Ventricle Craniopharyngioma.

World Neurosurg. 2016 Apr 20;

Authors: Nishioka H, Fukuhara N, Yamaguchi-Okada M, Yamada S

Abstract
BACKGROUND: Extended endoscopic transsphenoidal surgery (EETS) is a safe and effective treatment for many suprasellar craniopharyngiomas, including those with third-ventricle involvement. Craniopharyngioma entirely within the third ventricle (purely intraventricular type), however, is generally regarded unsuitable for treatment with EETS.
CASE DESCRIPTION: Three patients underwent total removal of a purely intraventricular craniopharyngioma with inferior extension via EETS by direct incision of the bulging, stretched ventricular floor and fine dissection from the ventricular wall. In two patients with an anteriorly displaced chiasm, the space between the chiasm and pituitary stalk created a wide corridor to the ventricle, whereas in the third case, in which the infrachiasmal space was somewhat narrowed, partial sacrifice of the pituitary gland was necessary to obtain sufficient space. Despite preservation of the stalk in two patients, hypoptuitarism and diabetes insipidus developed after surgery. There was no other complication including obesity.
CONCLUSIONS: Selected patients with purely intraventricular craniopharyngioma can be effectively and safely treated with EETS. Those with inferior extension in the interpeduncular fossa and anterior displacement of the chiasm may be suitable candidates.

PMID: 27108029 [PubMed - as supplied by publisher]

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