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Παρασκευή 29 Απριλίου 2016

Synchronous metastatic skull base chordoma to the breast: case report and literature review.

Synchronous metastatic skull base chordoma to the breast: case report and literature review.

Curr Oncol. 2016 Apr;23(2):e154-7

Authors: Shakir SI, Pelmus M, Florea A, Boileau JF, Guiot MC, Di Maio S, Muanza TM

Abstract
CLINICAL SCENARIO: During routine staging work-up for a left breast mass, a 68-year-old woman complained of dysphagia and dysphonia. During further investigations, a left-sided lesion at the foramen magnum was observed on brain imaging. Both lesions were biopsied and showed a classical chordoma.
MANAGEMENT: The skull-base lesion and the breast lesion were surgically resected, and adjuvant radiotherapy was given.
SUMMARY: Chordoma is a rare primary central nervous system tumour that seldom metastasizes. The lung is the most common site of metastasis. Synchronous breast metastasis from a skull-base chordoma is very rare, and a safe management option includes a maximum resection followed by adjuvant radiotherapy.

PMID: 27122985 [PubMed]



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