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Τετάρτη 4 Μαΐου 2016

Engineering protein interfaces yields ferritin disassembly and reassembly under benign experimental conditions

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Chem. Commun., 2016, Accepted Manuscript
DOI: 10.1039/C6CC03108K, Communication
Hai Chen, Shengli Zhang, Chuanshan Xu, Guanghua Zhao
Ferritin nanocages are promising platforms for drug encapsulation. However, extreme conditions (pH [less-than-or-equal] 2) required for dissociation limit their application. Here, we engineered protein interfaces to yield ferritin nanocages which...
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