Source:Journal of Neuroscience Methods
Author(s): David M. Halliday, Mohd Harizal Senik, Carl Stevenson, Rob Mason
BackgroundThe ability to infer network structure from multivariate neuronal signals is central to computational neuroscience. Directed network analyses typically use parametric approaches based on auto-regressive (AR) models, where networks are constructed from estimates of AR model parameters. However, the validity of using low order AR models for neurophysiological signals has been questioned. A recent article introduced a non parametric approach to estimate directionality in bivariate data, non parametric approaches are free from concerns over model validity.New MethodWe extend the non parametric framework to include measures of directed conditional independence, using scalar measures that decompose the overall partial correlation coefficient summatively by direction, and a set of functions that decompose the partial coherence summatively by direction. A time domain partial correlation function allows both time and frequency views of the data to be constructed. The conditional independence estimates are conditioned on a single predictor.ResultsThe framework is applied to simulated cortical neuron networks and mixtures of Gaussian time series data with known interactions. It is applied to experimental data consisting of local field potential recordings from bilateral hippocampus in anaesthetised rats.Comparison with Existing Method(s). The framework offers a non parametric approach to estimation of directed interactions in multivariate neuronal recordings, and increased flexibility in dealing with both spike train and time series data.ConclusionsThe framework offers a novel alternative non parametric approach to estimate directed interactions in multivariate neuronal recordings, and is applicable to spike train and time series data
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/24DhFRT
via IFTTT
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου