Propranolol-induced gingival hyperplasia with Nager syndrome: A rare adverse drug reaction.

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Propranolol-induced gingival hyperplasia with Nager syndrome: A rare adverse drug reaction.

J Adv Pharm Technol Res. 2016 Apr-Jun;7(2):64-8

Authors: Raheel SA, Kujan OB, Tarakji B, Umar D, Ibrahim S

Abstract
Drug reactions are a group of reactionary lesions generally show their manifestations in the oral cavity. The drug reactions may vary from local rashes to well-developed swellings in the oral cavity especially involving the gingiva. Most of the drug reactions are asymptomatic and commonly triggered from the active metabolite of a drug used for a long time. Nager syndrome is a group of acrofacial dysostosis that usually results in craniofacial and limb malformations. The craniofacial defects are very similar to the mandibulofacial dysostosis. A very early intervention is needed for the habilitation of the patient especially when it is concerned with speech and language development. This paper reports a case of a 32-year-old female with craniofacial, limb, and skeletal abnormalities along with a drug-induced gingival hyperplasia.

PMID: 27144155 [PubMed]

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