Iododerma from Contrast Material: NEJM Case Report

• NEJM reports a image case of iododerma, patient after  Intravenous urography, Several hours later, generalized pustular eruptions developed, with multiple coalescing vesicles and pus-filled bullae observed on the patient's face and ears, his trunk, and his arms and legs. 

• Although its pathogenesis is not understood, delayed iodine clearance and the induction of neutrophil degranulation have been proposed as mechanisms. 

• Treatment with thalidomide was initiated, and the skin lesions completely resolved within 4 weeks.

Reference: Iododerma from Contrast Material. Juan Guillermo Chalela, M.D., and Laura Aguilar, M.D. N Engl J Med 2016; 374:2477June 23, 2016DOI: 10.1056/NEJMicm1512512

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