The use of magnetic resonance imaging in the evaluation of upper airway structures in paediatric obstructive sleep apnoea syndrome. A systematic review and meta-analysis.

The use of magnetic resonance imaging in the evaluation of upper airway structures in paediatric obstructive sleep apnoea syndrome. A systematic review and meta-analysis.

Dentomaxillofac Radiol. 2016 Jul 20;:20160136

Authors: Patini R, Arrica M, Di Stasio E, Gallenzi P, Cordaro M

Abstract
OBJECTIVE: A systematic review was conducted to assess the effectiveness of magnetic resonance imaging (MRI) in evaluating upper airway structures in children affected by obstructive sleep apnoea syndrome (OSAS).
METHODS: A literature search was performed in the CENTRAL, Web of Science, Scopus and PubMed databases from their inceptions to 31/03/2016, including available English published randomised controlled trials (RCT) and controlled clinical trials (CCT) assessing the use of MRI integrated with traditional polysomnography (PSG) among children up to 15 years of age affected by OSAS. The primary outcome was to evaluate the efficacy of MRI in analysing the upper airway total volume among healthy children compared to children affected by OSAS. Secondary outcomes were to compare the efficacy of MRI in analysing the upper airway cross-sectional area in the areas adjacent to the adenoids and tonsils, adenoid and tonsil volume, soft tissue and maxillofacial bone parameters in the same sample. Results were expressed using a random-effects model and mean differences (MD) with 95% confidence intervals (CI).
RESULTS: The search yielded 1,005 titles in total and using the selection process narrowed to three, which were all assessed as indicating an unclear level of risk of bias. The meta-analysis found evidence in MRI effectiveness to evaluate differences in the upper airway total volume between paediatric patients affected by OSAS, and non affected paediatric patients (MD -0.56 cm(3); 95% CI -1.05 to -0.07).
CONCLUSIONS: Basing on the current evidence, although MRI could be considered effective to evaluate upper airway structures in children affected by OSAS, PSG is still the golden standard and further studies are required to verify MRI reliability.

PMID: 27440304 [PubMed - as supplied by publisher]

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