Abstract
In the systemic treatment of moderate-to-severe psoriasis, monotherapy is usually effective. However, some patients require combination therapy to adequately control their disease1,2. In fact, data from recent european reports indicate that biological therapy is given concomitantly with traditional systemic drugs in up to 30% of psoriasis patients1,3. Combination therapy of cyclosporin (CyA) with biologic drugs, particularly etanercept and adalimumab, has been rarely reported in the literature, including non-randomized trials and case reports1,4-8.
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