Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M [Immunology and Inflammation]

Positive-stranded RNA viruses, such as hepatitis C virus (HCV), assemble their viral replication complexes by remodeling host intracellular membranes to a membranous web. The precise composition of these replication complexes and the detailed mechanisms by which they are formed are incompletely understood. Here we show that the human immunity-related GTPase...

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