Circumscribed palmoplantar hypokeratosis: successful treatment with the 10,600-nm carbon dioxide fractional laser

Abstract

Circumscribed palmoplantar hypokeratosis (CPH) is a rare benign dermatosis of unknown etiology with characteristic clinical features presenting as a round well-demarcated depressed erythematous lesion on the palm and sole. The typical histologic features include an abrupt decrease in thickness of stratum corneum, forming a sharp stair at the edge.¹ Although various therapies have been tried, none have been established as a treatment of choice.^1,2 Here, we report a case of CPH successfully treated with the 10,600-nm carbon dioxide fractional laser (CO₂FL).

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