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Τρίτη 30 Μαΐου 2017

Lewis acid catalyzed cascade annulation of alkynols with [small alpha]-ketoesters: A facile access to [gamma]-spiroketal-[gamma]-lactones

Chem. Commun., 2017, Accepted Manuscript
DOI: 10.1039/C7CC03668J, Communication
Ravindar Kontham, Digambar Abasaheb Kambale, Sagar Sudam Thorat, Madhukar Shivaji Pratapure, Rajesh G. Gonnade
A novel Lewis acid catalyzed intermolecular cascade annulation of alkynols with [small alpha]-ketoesters has been developed. This simple and efficient cascade annulation proceeds through a 5-exo-dig cyclization of alkynols followed by...
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