Comparing the Effectiveness of Fractional CO2 Laser and the Combination Therapy with Micro-Needling and Topical 10% Trichloroacetic Acid to Remove Infra-Orbital Dark Circles in Tehran Women.

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Comparing the Effectiveness of Fractional CO2 Laser and the Combination Therapy with Micro-Needling and Topical 10% Trichloroacetic Acid to Remove Infra-Orbital Dark Circles in Tehran Women.

J Cosmet Laser Ther. 2017 Jun 16;:

Authors: Zamanian A, Azizi M, Ghasemi M, Behrangi E, Naeji S

Abstract
BACKGROUND: Infra-orbital dark circles in now identified as a cosmetic problem which should be considered in treatment issue. The present study aimed to assess and compare the clinical efficiency of the combination of micro-needling and 10% trichloroacetic acid (TCA) cream as well as carbon dioxide laser in the management of infra-orbital dark circles.
METHODS: This randomized clinical trial was performed on women ranged 28 to 62 years that complained of infra-orbital dark circles. The patients were randomly assigned to treat with micro-needling combined, using TCA 10% cream topically or CO2 laser. The treatment period in each group included three sessions with an interval of one month between sessions. The assessment was based on both subjective and objective methods.
RESULTS: the mean of ΔE (the difference in the intensity of darkening at infra-orbital point and other points of the face) was significantly higher in laser group than in another group in all visit sessions. The patients who treated with the laser were specified to have a higher level of satisfaction in fifth visit when compared to those who received another treatment method.
CONCLUSION: Regarding clinical effectiveness and the patients' compliance, fractional CO2 laser was more preferred in the combination therapy with micro-needling and topical TCA for removing infra-orbital dark circles.

PMID: 28622082 [PubMed - as supplied by publisher]

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