Abstract
This narrative review provides an evidence-based overview of existing literature on the epidemiology, clinicopathological characteristics and prognostic outcomes of tumours arising in patients with multiple primary melanomas (MPM). PubMed and MEDLINE were searched for original research papers and review articles from 2000 to 2016 using the term 'multiple primary melanoma.' Population-wide increases in life expectancy, advances in early detection and increasing incidence of melanoma give rise to an expanding group of patients that are at an increased risk of developing subsequent primary tumours.
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