Hospitalization and outcomes attributed to epidermal necrolysis in United States: Predictors of Mortality

Abstract

Acute life-threatening mucocutaneous reactions characterized by extensive necrosis and detachment of the epidermis(epidermal necrolysis,EN) includes the spectrum of Stevens-Johnson syndrome (SJS, <10% body surface area), Toxic epidermal necrolysis (TEN, >20% BSA) and the SJS-TEN overlap(10-20%BSA). Prior older studies have revealed that the incidence of these rare conditions was estimated to be 1 to 6 cases per million person-years for SJS and 0.4 to 1.2 cases per million person-years for TEN. Current, large population based hospitalization outcomes attributed to EN in United States are lacking.

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