Acanthoma planoepitheliale hyperkeratoticum, lesions associated with BRAF- inhibitor in metastatic melanoma

Abstract

A 68-year-old woman was diagnosed with BRAF V600 mutation positive melanoma of unknown primary (MUP) with metastasis to the lung, liver and brain. According to local standards dabrafenib monotherapy was started in July 2016. Control CT performed after two months revealed disease stabilization. The tolerance of therapy was good, but after 2 months of treatment with dabrafenib the patient developed disseminated skin lesions with extended seborrheic keratosis G2 (according to international common toxicity criteria CTC).

This article is protected by copyright. All rights reserved.

http://ift.tt/2x5rDQA