Adipokines are dysregulated in patients with hidradenitis suppurativa

Abstract

Hidradenitis suppurativa (HS), is characterized by the appearance of painful subcutaneous nodules and dermal abscesses in the axillae, perineum and inframammary folds. The development of HS has been linked to factors such as cigarette smoking and obesity¹. Patients with HS are more likely to have metabolic syndrome than control populations and develop early cardiovascular diseases². Adipokines are signalling molecules secreted by adipose tissue and peripheral blood mononuclear cells. The expression of adipokines is dysregulated in obesity and cardiovascular diseases³.

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