T cell receptor sequencing reveals decreased diversity 18 years after early thymectomy

Publication date: Available online 1 September 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Judith Gudmundsdottir, Christina Lundqvist, Hanna IJspeert, Eva van der Slik, Sólveig Óskarsdóttir, Susanne Lindgren, Vanja Lundberg, Martin Berglund, Jenny Lingman-Framme, Esbjörn Telemo, Mirjam van der Burg, Olov Ekwall

Teaser

Next generation T and B cell receptor sequencing in individuals 18 years after early thymectomy (n=11) due to congenital cardiac malformation reveals decreased diversity in both helper and cytotoxic T cell receptor repertoires whereas the B cell repertoire remains unaffected.


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