PTIP chromatin regulator controls development and activation of B cell subsets to license humoral immunity in mice [Immunology and Inflammation]

B cell receptor signaling and downstream NF-κB activity are crucial for the maturation and functionality of all major B cell subsets, yet the molecular players in these signaling events are not fully understood. Here we use several genetically modified mouse models to demonstrate that expression of the multifunctional BRCT (BRCA1...

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