Cortical inhibitory function in cervical dystonia

Dystonia is a hyperkinetic movement disorder characterized by the presence of involuntary muscle contractions producing abnormal twisting movements and/or postures(Albanese et al., 2013). In primary or isolated dystonia(Albanese et al., 2013), widespread and generalized loss of inhibition within the central nervous system is a key pathological finding(Berardelli et al., 1998; Hallett, 2011). The inhibitory deficit, however, may not reflect a single underlying neurophysiological mechanism. Rather, inhibition may refer to a range of neural mechanisms.

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